Patents Assigned to Flamel Ireland Limited
  • Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
    Patent number: 11896572
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: August 8, 2023
    Date of Patent: February 13, 2024
    Assignee: Flamel Ireland Limited
    Inventors: Jordan Dubow, Hervé Guillard, Claire Mégret, Jean-François Dubuisson
  • Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
    Patent number: 11839597
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: March 8, 2021
    Date of Patent: December 12, 2023
    Assignee: Flamel Ireland Limited
    Inventors: Claire Megret, Herve Guillard, Jean-Francois Dubuisson
  • Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
    Patent number: 11826335
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: January 12, 2023
    Date of Patent: November 28, 2023
    Assignee: Flamel Ireland Limited
    Inventors: Jordan Dubow, Hervé Guillard, Claire Mégret, Jean-François Dubuisson
  • Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
    Patent number: 11779557
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: February 7, 2022
    Date of Patent: October 10, 2023
    Assignee: Flamel Ireland Limited
    Inventors: Jordan Dubow, Cendrine Grangeon, Hervé Guillard, Claire Mégret, Jean-François Dubuisson
  • Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
    Patent number: 11766418
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: December 6, 2022
    Date of Patent: September 26, 2023
    Assignee: Flamel Ireland Limited
    Inventors: Jordan Dubow, Hervé Guillard, Claire Mégret, Jean-François Dubuisson
  • Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
    Patent number: 11602512
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: October 8, 2021
    Date of Patent: March 14, 2023
    Assignee: Flamel Ireland Limited
    Inventors: Jordan Dubow, Hervé Guillard, Claire Mégret, Jean-François Dubuisson
  • Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
    Patent number: 11602513
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: October 8, 2021
    Date of Patent: March 14, 2023
    Assignee: Flamel Ireland Limited
    Inventors: Jordan Dubow, Hervé Guillard, Claire Mégret, Jean-François Dubuisson
  • Methods of administering gamma hydroxybutyrate formulations after a high-fat meal
    Patent number: 11583510
    Abstract: Provided herein are methods of administering a once-nightly dosage of gamma-hydroxybutyrate after a high-fat meal.
    Type: Grant
    Filed: February 7, 2022
    Date of Patent: February 21, 2023
    Assignee: Flamel Ireland Limited
    Inventors: Julien Grassot, David Monteith, Hervé Guillard, Claire Mégret, Jean-François Dubuisson
  • Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
    Patent number: 11504347
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: October 8, 2021
    Date of Patent: November 22, 2022
    Assignee: Flamel Ireland Limited
    Inventors: Julien Grassot, Hervé Guillard, Claire Mégret, Jean-François Dubuisson
  • Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state
    Patent number: 11400065
    Abstract: Oral pharmaceutical compositions of sodium oxybate having improved pharmacokinetic properties when administered less than two hours after eating are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: August 2, 2022
    Assignee: Flamel Ireland Limited
    Inventors: Julien Grassot, Cendrine Grangeon, Jordan Dubow
  • Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
    Patent number: 11065224
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: July 20, 2021
    Assignee: Flamel Ireland Limited
    Inventors: Claire Megret, Herve Guillard, Jean-Francois Dubuisson
  • Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
    Patent number: 11052061
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: May 22, 2019
    Date of Patent: July 6, 2021
    Assignee: Flamel Ireland Limited
    Inventors: Claire Megret, Herve Guillard, Jean-Francois Dubuisson
  • Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
    Patent number: 11000498
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: May 11, 2021
    Assignee: Flamel Ireland Limited
    Inventors: Claire Megret, Herve Guillard, Jean-Francois Dubuisson, Julien Grassot
  • Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
    Patent number: 10973795
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: May 22, 2019
    Date of Patent: April 13, 2021
    Assignee: Flamel Ireland Limited
    Inventors: Claire Megret, Herve Guillard, Jean-Francois Dubuisson
  • Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
    Patent number: 10952986
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: March 23, 2021
    Assignee: Flamel Ireland Limited
    Inventors: Claire Megret, Herve Guillard, Jean-Francois Dubuisson
  • Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state
    Patent number: 10925844
    Abstract: Oral pharmaceutical compositions of sodium oxybate having improved pharmacokinetic properties when administered less than two hours after eating are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: February 23, 2021
    Assignee: Flamel Ireland Limited
    Inventors: Julien Grassot, Cendrine Grangeon, Jordan Dubow
  • Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
    Patent number: 10736866
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: August 11, 2020
    Assignee: Flamel Ireland Limited
    Inventors: Claire Mégret, Hervé Guillard, Jean-François Dubuisson
  • Cysteine composition and injection
    Patent number: 10543186
    Abstract: Cysteine compositions comprising less than about 400 ?g/L of aluminum. For example, solutions of cysteine comprising a pharmaceutically acceptable solvent, cysteine, and less than about 145 ?g/L of aluminum, wherein the solution is devoid of visible particulate matter. Cysteine compositions described herein may be suitable for injection. For example, disclosed cysteine solutions may be provided intravenously to meet amino acid nutritional requirement in individuals receiving total parenteral nutrition. Also provided are processes for preparing cysteine compositions, and methods for providing cysteine to individuals in need thereof.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: January 28, 2020
    Assignee: Flamel Ireland Limited
    Inventors: Angela Sutterer, Jill Simpson, Gauthier Pouliquen, Alain Constancis, Pierre Danner
  • Cysteine composition and injection
    Patent number: 10493051
    Abstract: Cysteine compositions comprising less than about 400 ?g/L of aluminum. For example, solutions of cysteine comprising a pharmaceutically acceptable solvent, cysteine, and less than about 145 ?g/L of aluminum, wherein the solution is devoid of visible particulate matter. Cysteine compositions described herein may be suitable for injection. For example, disclosed cysteine solutions may be provided intravenously to meet amino acid nutritional requirement in individuals receiving total parenteral nutrition. Also provided are processes for preparing cysteine compositions, and methods for providing cysteine to individuals in need thereof.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: December 3, 2019
    Assignee: Flamel Ireland Limited
    Inventors: Angela Sutterer, Jill Simpson, Gauthier Pouliquen, Alain Constancis, Pierre Danner
  • Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
    Patent number: 10272062
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: April 30, 2019
    Assignee: Flamel Ireland Limited
    Inventors: Claire Mégret, Hervé Guillard, Jean-François Dubuisson