Patents Assigned to FLATLEY DISCOVERY LAB
  • Phthalazinone compounds and methods for the treatment of cystic fibrosis
    Patent number: 10889576
    Abstract: The invention relates to a compound of Formula I and methods of treating CFTR (cystic fibrosis transmembrane conductance regulator) mediated diseases, in particular cystic fibrosis, comprising the step of administering a therapeutically effective amount of a compound of Formula I to a patient in need thereof:
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: January 12, 2021
    Assignee: Flatley Discovery Lab, LLC
    Inventor: Bridget M. Cole
  • Triazolopyridine compounds and methods for the treatment of cystic fibrosis
    Patent number: 10472357
    Abstract: The invention relates to a compound of Formula I or IA and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof:
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: November 12, 2019
    Assignee: Flatley Discovery Lab, LLC
    Inventors: Bridget M. Cole, Richard A. Nugent, Paul T. Smith, Jr.
  • Pyridazinone compounds and methods for the treatment of cystic fibrosis
    Patent number: 10370366
    Abstract: The invention relates to a compound of having the following formulae and methods of treating cystic fibrosis:
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: August 6, 2019
    Assignee: Flatley Discovery Lab, LLC
    Inventors: Bridget M. Cole, Richard A. Nugent, Andrew Kolodziej, Karen Handley, Yevgen Barsukov
  • Phthalazinone compounds and methods for the treatment of cystic fibrosis
    Patent number: 10280160
    Abstract: The invention relates to a compound of Formula I and methods of treating CFTR (cystic fibrosis transmembrane conductance regulator) mediated diseases, in particular cystic fibrosis, comprising the step of administering a therapeutically effective amount of a compound of Formula I to a patient in need thereof:
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: May 7, 2019
    Assignee: FLATLEY DISCOVERY LAB, LLC
    Inventor: Bridget M. Cole
  • Compounds and methods for the treatment of cystic fibrosis
    Patent number: 10072017
    Abstract: The invention relates to a compound of Formula I or IA compositions comprising compounds of Formula I or IA, and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof:
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: September 11, 2018
    Assignee: Flatley Discovery Lab, LLC
    Inventors: Michael P. Zawistoski, Asmita Deshpande, Bridget M. Cole
  • Compounds and methods for the treatment of cystic fibrosis
    Patent number: 9944603
    Abstract: The invention relates to a compound of Formula I and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: April 17, 2018
    Assignee: FLATLEY DISCOVERY LAB, LLC
    Inventors: Michael P. Zawistoski, Yevgen Barsukov, Bridget M. Cole, Richard A. Nugent
  • Triazolopyridine compounds and methods for the treatment of cystic fibrosis
    Patent number: 9926315
    Abstract: The invention relates to a compound of Formula I or IA and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof:
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: March 27, 2018
    Assignee: Flatley Discovery Lab, LLC
    Inventors: Bridget M. Cole, Richard A. Nugent, Paul T. Smith, Jr.
  • Isoxazole compounds and methods for the treatment of cystic fibrosis
    Patent number: 9855249
    Abstract: The invention relates to a compound of Formula I and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or II to a patient in need thereof:
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: January 2, 2018
    Assignee: FLATLEY DISCOVERY LAB, LLC
    Inventors: Bridget M. Cole, Andrew Kolodziej
  • Pyridazinone compounds and methods for the treatment of cystic fibrosis
    Patent number: 9790215
    Abstract: The invention relates to a compound of Formula I and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I to a patient in need thereof:
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: October 17, 2017
    Assignee: FLATLEY DISCOVERY LAB, LLC
    Inventors: Bridget M. Cole, Richard A. Nugent, Andrew Kolodziej, Karen Handley, Yevgen Barsukov
  • Pyridazinone compounds and methods for the treatment of cystic fibrosis
    Patent number: 9783529
    Abstract: The invention relates to a compound of having the following formulae and methods of treating cystic fibrosis:
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: October 10, 2017
    Assignee: FLATLEY DISCOVERY LAB, LLC
    Inventors: Bridget M. Cole, Richard A. Nugent, Andrew Kolodziej, Karen Handley, Yevgen Barsukov
  • Compounds and methods for the treatment of cystic fibrosis
    Patent number: 9771327
    Abstract: The invention relates to a compound of Formula I and methods of treating CFTR (cystic fibrosis transmembrane conductance regulator) mediated diseases, in particular cystic fibrosis, comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof:
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: September 26, 2017
    Assignee: FLATLEY DISCOVERY LAB, LLC
    Inventors: Michael P. Zawistoski, Yevgen Barsukov, Bridget M. Cole, Richard A. Nugent
  • Phthalazinone compounds and methods for the treatment of cystic fibrosis
    Patent number: 9682969
    Abstract: The invention relates to a compound of Formula I and methods of treating CFTR (cystic fibrosis transmembrane conductance regulator) mediated diseases, in particular cystic fibrosis, comprising the step of administering a therapeutically effective amount of a compound of Formula I to a patient in need thereof:
    Type: Grant
    Filed: January 19, 2015
    Date of Patent: June 20, 2017
    Assignee: Flatley Discovery Lab, LLC
    Inventor: Bridget M. Cole
  • Triazolopyridine compounds and methods for the treatment of cystic fibrosis
    Patent number: 9573948
    Abstract: The invention relates to a compound of Formula I or IA and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof:
    Type: Grant
    Filed: October 6, 2015
    Date of Patent: February 21, 2017
    Assignee: Flatley Discovery Lab
    Inventors: Bridget M. Cole, Richard A. Nugent, Paul T. Smith, Jr.
  • Phthalazinone compounds and methods for the treatment of cystic fibrosis
    Patent number: 8937178
    Abstract: The invention relates to a compound of Formula I and methods of treating CFTR (cystic fibrosis transmembrane conductance regulator) mediated diseases, in particular cystic fibrosis, comprising the step of administering a therapeutically effective amount of a compound of Formula I to a patient in need thereof:
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 20, 2015
    Assignee: Flatley Discovery Lab
    Inventor: Bridget M. Cole
  • PYRIDAZINONE COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20150005300
    Abstract: The invention relates to a compound of having the following formulae and methods of treating cystic fibrosis:
    Type: Application
    Filed: March 13, 2014
    Publication date: January 1, 2015
    Applicant: FLATLEY DISCOVERY LAB
    Inventors: BRIDGET M. COLE, RICHARD A. NUGENT, ANDREW KOLODZIEJ, KAREN HANDLEY, YEVGEN BARSUKOV
  • COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20140371263
    Abstract: The invention relates to a compound of Formula I and methods of treating CFTR (cystic fibrosis transmembrane conductance regulator) mediated diseases, in particular cystic fibrosis, comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof:
    Type: Application
    Filed: March 13, 2014
    Publication date: December 18, 2014
    Applicant: FLATLEY DISCOVERY LAB
    Inventors: Michael P. Zawistoski, Yevgen Barsukov, Bridget M. Cole, Richard A. Nugent
  • COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20140371238
    Abstract: The invention relates to a compound of Formula I and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I or IA to a patient in need thereof:
    Type: Application
    Filed: March 13, 2014
    Publication date: December 18, 2014
    Applicant: FLATLEY DISCOVERY LAB
    Inventors: Michael P. Zawistoski, Yevgen Barsukov, Bridget M. Cole, Richard A. Nugent
  • PYRIDAZINONE COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20140371225
    Abstract: The invention relates to a compound of Formula I and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I to a patient in need thereof:
    Type: Application
    Filed: March 13, 2014
    Publication date: December 18, 2014
    Applicant: FLATLEY DISCOVERY LAB
    Inventors: Bridget M. Cole, Richard A. Nugent, Andrew Kolodziej, Karen Handley, Yevgen Barsukov
  • PHTHALAZINONE COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20140274933
    Abstract: The invention relates to a compound of Formula I and methods of treating CFTR (cystic fibrosis transmembrane conductance regulator) mediated diseases, in particular cystic fibrosis, comprising the step of administering a therapeutically effective amount of a compound of Formula I to a patient in need thereof:
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: FLATLEY DISCOVERY LAB
    Inventor: Bridget M. Cole