Abstract: Amorphous solid dispersions of the protein kinase inhibitor cabozantinib. The amorphous solid dispersions exhibit chemical and physical stability under stressed conditions. The amorphous solid dispersions may be suitable for use in pharmaceutical compositions for administration to human subjects or patients.
Type:
Grant
Filed:
June 23, 2025
Date of Patent:
March 3, 2026
Assignee:
Flex Pharma, LLC
Inventors:
Christian F. Wertz, Tzehaw Chen, Joseph McTarsney