Abstract: A tube clamp assembly (10) for clamping and supporting a rigid coupling (30) or a flexible elastomeric grommet (32). The tube clamp (10) includes a pair of oppositely facing clamping members (12u, 12l) each having a generally U-shaped cross section with at least one clamping seat (26) and an associated clamping hole (28) for mounting one of the coupling (30) and the grommet (32) between the clamping members (12u, 12l). The tube clamp (10) further includes a set of four arcuate flanges (52f, 52b; 54f, 54b) extending into the clamping hole (28) from the clamping seat (26). The flanges (52f, 52b; 54f, 54b) grip an elastomeric grommet (32) upon application of a predetermined clamping force to prevent removal of the grommet (32) from the tube clamp (10) and yield away from a rigid coupling (30) upon application of the predetermined clamping force to allow the rigid coupling (30) to be fully seated against the clamping seat (26).