Abstract: The present invention relates to the use of an oligonucleotide complementary to the sequence of human miR-203b-3p microRNA in the treatment of psoriasis-induced itching. The present invention concerns also a phospholipid vesicle comprising said oligonucleotide and the use of said phospholipid vesicle for the prevention and/or treatment of psoriasis-induced itching.
Type:
Application
Filed:
November 23, 2022
Publication date:
February 6, 2025
Applicant:
FLONEXT S.R.L.
Inventors:
Romina NASSINI, Pierangelo GEPPETTI, Francesco DE LOGU
Abstract: The present invention relates to TRPA1 channel antagonist compounds for use in the prevention and/or treatment of retinal diseases, in particular in the prevention and/or treatment of macular degeneration. The present invention also relates to an ophthalmic composition comprising at least one TRPA1 channel antagonist compound for topical ophthalmic use in the prevention and/or treatment of at least one degenerative retinal disease, preferably macular degeneration.
Type:
Application
Filed:
June 7, 2022
Publication date:
August 29, 2024
Applicant:
FLONEXT S.R.L.
Inventors:
Pierangelo GEPPETTI, Romina NASSINI, Francesco DE LOGU
Abstract: The present invention relates to compounds belonging to the pyrazolone class for use in the prevention and/or treatment of degenerative retinal diseases, in particular in the prevention and/or treatment of macular degeneration. The present invention also relates to a pharmaceutical composition comprising at least one compound belonging to the pyrazolone class, preferably a topical ophthalmic composition, for use in the prevention and/or treatment of degenerative retinal diseases, preferably macular degeneration.
Type:
Application
Filed:
June 7, 2022
Publication date:
August 15, 2024
Applicant:
FLONEXT S.R.L.
Inventors:
Pierangelo GEPPETTI, Romina NASSINI, Francesco DE LOGU