Patents Assigned to FLOREKY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE
  • Chimeric Relaxin Polypeptides Comprising an A and B Chain Derived From Different Relaxin Family Peptides
    Publication number: 20110092418
    Abstract: Provided herein are modified relaxin polypeptides wherein the B chain comprises the core amino acid sequence CGR-XXX-R-XX-I/V-XX-CG (SEQ ID NO:1), where X is any amino acid. Also provided are modified relaxin polypeptides comprising at least an A and a B chain, wherein the A and B chains are derived from different naturally occurring relaxins and wherein the B chain comprises the core amino acid sequence CGR-XXX-R-XX-I/V-XX-CG (SEQ ID NO:1), where X is any amino acid.
    Type: Application
    Filed: October 30, 2008
    Publication date: April 21, 2011
    Applicant: FLOREKY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE
    Inventors: Ross Alexander David Bathgate, Mohammed Akhter Hossain, Chrishan Surendran Samuel, John Desmond Wade, Geoffrey W. Tregear