Abstract: Disclosed is a method of delivering therapeutic carbon monoxide to the cells and tissues of a patient which comprises administering thereto a compound of the formula XBY1Y2C(O)V (I) or pharmaceutically acceptable salts thereof. In addition, disclosed is a method of delivering a drug to a diseased cell or tissue by administering a compound of formula I either wherein at least one of X is a drug containing an amino group or V is a drug containing an amino group or hydroxyl group less a hydrogen on the amino or hydroxyl group. Further disclosed are novel compounds of Formula I.
Type:
Grant
Filed:
April 30, 2020
Date of Patent:
June 7, 2022
Assignees:
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, FLORIDA SHOUTHWESTERN STATE COLLEGE, UNIVERSITY OF ALASKA ANCHORAGE
Inventors:
Nin N. Dingra, Theppawut Israsena Na Ayudhya