Patents Assigned to Florida State University Research Foundation, Inc.
  • Patent number: 11787709
    Abstract: A method for reacting a liquid phase chemical species includes the steps of providing liquid phase containing at least one liquid phase chemical species, providing a gas phase, and providing a reactor vessel for containing the liquid phase and the gas phase. The liquid phase and the gas phase are placed in the reactor vessel so as to form a liquid-gas interface between the liquid phase and the gas phase within the reactor vessel. A pulsed discharge cathode and anode are provided for creating a pulsed discharge electric field at the liquid-gas interface. A pulsed power input to the pulsed discharge cathode and anode is provided, thereby creating a plasma comprising ions at the liquid-gas interface. A secondary electric field is directed transverse to the liquid-gas interface, wherein the secondary electric field will drive ions from the gas phase into the liquid phase to react with the liquid phase species.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: October 17, 2023
    Assignee: FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Bruce R. Locke, Robert J. Wandell, Youneng Tang
  • Patent number: 11791075
    Abstract: The present invention provides for polycrystalline superconducting permanent magnets which are synthesized of doped superconducting (AE) Fe2As2 compounds, where AE denotes an alkaline earth metal, such as Ba, Sr, Mg or Ca. The superconducting permanent magnets of the present invention can be magnetized in their superconducting state by induced currents, resulting in trapped magnetization that scales with the size of the bulk material. The magnitude of the trapped field has been demonstrated to be over 1 T and is predicted to be over 10 T if the technology is scaled, which is much higher than the capabilities of permanent magnets and other superconducting polycrystalline bulks currently known in the art.
    Type: Grant
    Filed: August 15, 2019
    Date of Patent: October 17, 2023
    Assignees: The Florida State University Research Foundation, Inc., Japan Science and Technology Agency
    Inventors: Jeremy Weiss, Akiyasu Yamamoto, Eric Hellstrom
  • Patent number: 11781114
    Abstract: The subject invention concerns materials and methods for expansion of stem cells, such as mesenchymal stem cells (MSC), that improve translational success of the cells in the treatment of various conditions. The subject invention utilizes cell self-aggregation as a non-genetic means to enhance their therapeutic potency in a microcarrier bioreactor. In one embodiment of the method cells are cultured in a container or vessel in the presence of thermally responsive microcarriers (TRMs) wherein cells adhere to the surface of the TRMs. After a period of time the cell culture temperature is reduced so that the cells detach from the TRMs. The detached cells are allowed to form 3D aggregates. The 3D aggregates can be collected and treated to dissociate the cells. Dissociated cells can then be used for transplantation in methods of treatment or for in vitro characterization and study.
    Type: Grant
    Filed: April 6, 2020
    Date of Patent: October 10, 2023
    Assignee: FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventor: Teng Ma
  • Patent number: 11779570
    Abstract: The present invention concerns the use of compounds and compositions for the treatment or prevention of Flavivirus infections, such as dengue virus infections and Zika virus infections. Aspects of the invention include methods for treating or preventing Flavivirus virus infection, such as dengue virus and Zika virus infection, by administering a compound or composition of the invention, to a subject in need thereof; methods for inhibiting Flavivirus infections, such as dengue virus and Zika virus infections, in a cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits useful for treating or preventing Flavivirus infections, such as dengue virus and Zika virus infections.
    Type: Grant
    Filed: June 28, 2022
    Date of Patent: October 10, 2023
    Assignees: FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, Inc., The United States of America, as represented by the Secretary, Department of Health and Human Services, THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Hengli Tang, Emily M. Lee, Wei Zheng, Ruili Huang, Miao Xu, Wenwei Huang, Khalida Shamim, Guoli Ming, Hongjun Song
  • Publication number: 20230313296
    Abstract: Fluorescent collagen a1(I) and a2(I) mRNA compounds can be used to detect whether a test compound affects the binding of collagen a1(I) and/or a2(I) mRNAs to LARP6 protein. Fluorescent collagen a1(I) and a2(I) mRNA compounds include collagen a1(I) and a2(I) mRNA sequences that have been tagged with a fluorophore and have LARP6 binding affinity.
    Type: Application
    Filed: March 16, 2023
    Publication date: October 5, 2023
    Applicant: Florida State University Research Foundation, Inc.
    Inventor: Branko Stefanovic
  • Patent number: 11771668
    Abstract: The present invention concerns compositions comprising at least one niclosamide compound, such as niclosamide or a pharmaceutically acceptable salt thereof, and at least one permeability enhancer, such as glycerol or dimethylpalmityl-ammonio propanesulfonate (PPS), and their use of such compositions as niclosamide agents. Advantageously, the niclosamide compound is capable of being transported across a Caco-2 cell membrane by at least 150% relative to the amount capable of being transported across the Caco-2 cell membrane in the absence of the permeability enhancer. Compositions, including oral dosage forms, and methods for delivering niclosamide compounds, such as for treatment or prevention of human coronavirus infections, are also provided.
    Type: Grant
    Filed: April 2, 2021
    Date of Patent: October 3, 2023
    Assignee: FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Eric Holmes, Gary Ostrander
  • Patent number: 11761067
    Abstract: Provided herein are techniques for making low-carbon steels with high surface hardness. A technique includes heating a low-carbon steel precursor material in a furnace to form molten steel material, increasing the free oxygen content of the molten steel material to a predetermined level, and then solidifying the molten steel material having the predetermined oxygen level to produce a steel structure by cooling the molten steel material at a predetermined cooling rate. The predetermined oxygen level and the predetermined cooling rate are effective to produce the low-carbon steel with a high surface hardness. The low-carbon steel may have inclusions smaller than about 1 ?m.
    Type: Grant
    Filed: October 14, 2019
    Date of Patent: September 19, 2023
    Assignee: THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Huigai Li, Ke Han, Yan Xin, Shaobo Zheng, Liuxing Wang, Qijie Zhai
  • Patent number: 11751410
    Abstract: Methods of passivating a surface. The methods may include providing a mixture including a liquid and a derivative of quinacridone, applying the mixture to a first surface of a film that includes a metal halide perovskite, and annealing the film for a time and a temperature effective to convert the derivative of quinacridone to quinacridone. Composite materials and electronic devices also are provided.
    Type: Grant
    Filed: March 2, 2021
    Date of Patent: September 5, 2023
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Biwu Ma, Qingquan He
  • Patent number: 11746391
    Abstract: Disclosed are non-naturally occurring zebrafish, such as transgenic zebrafish, which comprise a mutation in the rhodopsin (rho) gene. Also disclosed are methods of identifying compounds useful in treating retinal-specific defects and disorders, such as degeneration. Further disclosed are methods of identifying mutations in the rhodopsin gene that can cause retinal-specific defects.
    Type: Grant
    Filed: October 7, 2020
    Date of Patent: September 5, 2023
    Assignee: The Florida State University Research Foundation, Inc.
    Inventor: James Fadool
  • Patent number: 11739984
    Abstract: Various implementations include solar thermal energy collection system comprising a solar energy concentrator, a heat transfer fluid, an absorber pipe. The absorber pipe includes a pipe wall and has a central longitudinal axis. The pipe wall has an inner surface and an outer surface. The inner surface has a first contour defining alternating peaks and troughs along a length of the absorber pipe. The outer surface has a second contour defining alternating peaks and troughs along the length of the absorber pipe. The inner surface defines the entire flow path for the heat transfer fluid through the absorber pipe. The first contour, as viewed through an axial cross section of the absorber pipe, forms sinusoidal waves on each side of and spaced apart from the central longitudinal axis. The sinusoidal waves on each side of the central longitudinal axis are symmetrical with respect to the central longitudinal axis.
    Type: Grant
    Filed: March 31, 2021
    Date of Patent: August 29, 2023
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Sam Yang, Juan Carlos Ordonez
  • Patent number: 11728510
    Abstract: A solid conductor including: a compound represented by Formula 1, a compound represented by Formula 2, or a combination thereof Li1+x+y?zTa2?xMxP1?yQyO8?zXz??Formula 1 wherein, in Formula 1, M is an element having an oxidation number of +4, Q is an element having an oxidation number of +4, X is a halogen, a pseudohalogen, or a combination thereof, and 0?x?2, 0?y<1, and 0?z?2, except that cases i) x and y and z are simultaneously 0, ii) M is Hf, X is F, x is 1, y is 0, and z is 1, iii) M is Hf, X is Cl, x is 2, y is 0, and z is 2, and iv) M is Hf, X is F, x is 2, y is 0, and z is 2, Li1+x+y?zTa2?xMxP1?yQyO8·zLiX??Formula 2 wherein, in Formula 2, M is an element having an oxidation number of +4, Q is an element having an oxidation number of +4, X is a halogen, a pseudohalogen, or a combination thereof, and 0?x?2, 0?y<1, and 0?z2, except that cases i) x and y and z are simultaneously 0, ii) M is Hf, X is F, x is 1, y is 0, and z is 1, iii) M is Hf, X is Cl, x is 2, y is 0, and z is 2, and iv)
    Type: Grant
    Filed: May 22, 2020
    Date of Patent: August 15, 2023
    Assignees: SAMSUNG ELECTRONICS CO., LTD., THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Ryounghee Kim, Jeongju Cho, Lincoln Miara, Sawankumar Patel, Yan Wang, Yan-Yan Hu, Hyeokjo Gwon, Sewon Kim, Jusik Kim, Sungkyun Jung
  • Patent number: 11730047
    Abstract: A new type of charge transport layer based on organometal halide perovskite for highly efficient organic light emitting diodes (OLEDs) is demonstrated. By solution processing of halide perovskite precursors, smooth essentially pure perovskite thin films may be prepared with high transparency and conductivity. Solution processed multilayer OLED with this perovskite-based hole transport layer outperforms a device with a PEDOT:PSS layer.
    Type: Grant
    Filed: September 17, 2021
    Date of Patent: August 15, 2023
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Biwu Ma, Yu Tian
  • Patent number: 11720831
    Abstract: Devices and methods of allocating distributed energy resources (DERs) to loads connected to a microgrid based on the cost of the DERs are provided. The devices and methods may determine one or more microgrid measurements. The devices and methods may determine one or more real-time electricity prices associated with utility generation sources. The devices and methods may determine one or more forecasts. The devices and methods may determine a cost associated with one or more renewable energy sources within the microgrid. The devices and methods may determine an allocation of the renewable sources to one or more loads in the microgrid.
    Type: Grant
    Filed: May 19, 2021
    Date of Patent: August 8, 2023
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Richard H. Meeker, Md Omar Faruque, Juan Ospina, Alvi Newaz, Emmanuel Collins, Griffin Francis, Nikhil Gupta
  • Patent number: 11721462
    Abstract: A high temperature superconductor (HTS) cable comprising at least one coil form comprising a helical channel formed on an exterior surface of the coil form and the helical channel extending at least partially along an axial length of the coil form and a plurality of high temperature superconductor (HTS) tape layers positioned within the helical channel of the coil form. A method for operating a winding machine to produce a high temperature superconductor (HTS) cable comprising a plurality of coil forms comprising a helical channel formed on an exterior surface of the coil form.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: August 8, 2023
    Assignee: The Florida State University Research Foundation, Inc.
    Inventor: Thomas Andrew Painter
  • Publication number: 20230238895
    Abstract: A dual multi-level inverter topology with reduced switch count and small DC-link capacitor is provided. The inverter topology provides multi-level inverter operation without requiring a neutral point connection that is commonly present in a stacked capacitor topology (for example, a topology including two capacitors).
    Type: Application
    Filed: December 27, 2022
    Publication date: July 27, 2023
    Applicants: The Florida State University Research Foundation, Inc., General Motors
    Inventors: Jinyeong MOON, Woongkul LEE, Muhammad ALVI
  • Patent number: 11703555
    Abstract: Apparatuses and methods for removing caps, such as NMR rotor caps. The apparatuses and methods may permit caps to be removed in a manner that minimizes damage to equipment and instruments. The apparatuses may include a plate defining an aperture, and two screws arranged in the plate, such as a tightening screw and at least one pushing screw.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: July 18, 2023
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Thierry Dubroca, Bianca Trociewitz, Johannes McKay, Frederic Mentink-Vigier
  • Patent number: 11673988
    Abstract: Disclosed are multi-block polymers and blends thereof having high electrical conductivity and adhesion. Also disclosed herein are methods of making the same.
    Type: Grant
    Filed: January 7, 2021
    Date of Patent: June 13, 2023
    Assignee: The Florida State University Research Foundation, Inc.
    Inventor: Hoyong Chung
  • Patent number: 11667593
    Abstract: Methods of forming arenes, including asymmetrical arenes, such as asymmetrical pyrene derivatives. Substituents of starting materials may be selected to direct a photochemical cascade and possibly a 1,2-aryl shift. The methods may include a Mallory cyclization, which is controlled, at least in part, by substituents of the starting materials. Compounds and compositions including asymmetrical arenes.
    Type: Grant
    Filed: September 6, 2022
    Date of Patent: June 6, 2023
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Nikolas Ramos Dos Santos, Igor Alabugin, Alexandria Palazzo
  • Publication number: 20230170827
    Abstract: An improved magnetic-levitation-based low-gravity simulator (MLS) is provided. The MLS comprises one or more gradient-field Maxwell coils that are provided within a superconducting magnet. When a current is provided to the one or more Maxwell coils and the superconducting magnet, a simulated low-gravity region is produced within the MLS. An object may be provided within this low-gravity region and may levitate within the region. The MLS may be used to test the impacts of low-gravity environments (for example, extraterrestrial environments) on different types of objects. Compared to an existing solenoid MLS, the improved MLS described herein includes a much larger volume low-gravity region at a lower energy expenditure.
    Type: Application
    Filed: November 15, 2022
    Publication date: June 1, 2023
    Applicant: The Florida State University Research Foundation, Inc.
    Inventors: Wei Guo, Hamid Sanavandi
  • Patent number: 11658336
    Abstract: A compound of Formula 1 Li1+(4?a)?Hf2??Ma?(PO4??)3??(1) is disclosed, wherein M is at least one cationic element having a valence of a, wherein 0<???, 1?a?4, and 0???0.1. Also described are an electrolyte composition, a separator, a protected positive electrode, a protected negative electrode, and a lithium battery, each including the compound of Formula 1.
    Type: Grant
    Filed: August 26, 2019
    Date of Patent: May 23, 2023
    Assignees: SAMSUNG ELECTRONICS CO., LTD., THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Yan Wang, Lincoln Miara, Yan-Yan Hu, Xuyong Feng