Patents Assigned to Fluid Imaging Technologies, Inc.
  • Publication number: 20230419479
    Abstract: A system and method for classifying images of particles detected in a fluid. Particles images of a dataset are preprocessed through computer processing and analyze for classification with an Artificial Intelligence (AI) classifier to predict which of one or more pre-defined particle types are present in the particle images of the dataset. The AI classifier is trained with smart training data and a smart training method to enable enhanced recognition of variations between dataset particle images and one or more pre-defined particle types. Particle images are subject to extreme augmentation to facilitate robust classification performance. The invention includes detecting anomalies of the particle images of the dataset to detect images that are inconsistent with images known to be of the class the image is assigned during preliminary image classification. Fake particle images may be generated to improve the detection of anomalies of the particle images classified.
    Type: Application
    Filed: June 28, 2022
    Publication date: December 28, 2023
    Applicant: Yokogawa Fluid Imaging Technologies, Inc.
    Inventor: Austin Venelinov Daniels
  • Patent number: 10761007
    Abstract: An imaging flow cytometry system and method which includes a flow chamber, light obscuration analysis and imaging optics, image capturing system, device to regulate fluid flow through the chamber, and backlighting generator. The flow cell is configured so that light obscuration signals can be detected from the same passing particles that are imaged.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: September 1, 2020
    Assignee: Yokogawa Fluid Imaging Technologies, Inc.
    Inventors: Christian K. Sieracki, Kent A. Peterson, Axel Wilde
  • Patent number: 9983115
    Abstract: A particle detection system with a detection mechanism that includes detectors positioned to detect two different ranges of fluorescence produced by particles in the fluid in a flow chamber. Each of the detectors is arranged to generating a trigger signal whenever fluorescence is detected. The system and related method enhance the accuracy and sensitivity of blue-green algae monitoring by utilizing imaging flow cytometry combined with particle analysis and the measurement of the ratio of each particle's phycocyanin to chlorophyll b detected by using the two detectors configured for detection of two different fluorescence ranges, one associated with the phycocyanin and the other associated with the chlorophyll b. Captured images are be used in comparison to known images of a library of images using a support vector machine classifier.
    Type: Grant
    Filed: September 21, 2015
    Date of Patent: May 29, 2018
    Assignee: Fluid Imaging Technologies, Inc.
    Inventors: Christian K. Sieracki, Peter Wolfe, William H. Nelson, Kent A. Peterson
  • Patent number: 9151943
    Abstract: An imaging system with an imaging mechanism which includes polarization analyzers, which may be crossed polarization analyzers, positioned to provide birefringence images of particles in the fluid passing through the flow chamber. Captured images are of high resolution and may be used in comparison to known images of a library of images. The system and related method enhance the accuracy and sensitivity of particle monitoring by utilizing birefringence imaging combined with particle analysis and the detection of each particle's characteristic features, such as crystalline features. The system includes a scatter detector used to trigger backlighting of the flow chamber and capture images of particles therein.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: October 6, 2015
    Assignee: Fluid Imaging Technologies, Inc.
    Inventors: Christian K. Sieracki, William H. Nelson, Robert M. Grimm, Scott Ellis
  • Patent number: 8994945
    Abstract: A method for determining the effectiveness of the treatment of a fluid for the purpose of reducing or eliminating particles in the fluid. The method includes the steps of obtaining samples of the fluid before and after treatment, delivering the samples to a particle imaging system, obtaining image information of particles in the samples, including particle colors, and comparing the difference in particle color from the first sample to the second sample. A change in particle color detected is indicative of particle death.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: March 31, 2015
    Assignee: Fluid Imaging Technologies, Inc.
    Inventors: Matthew Duplisea, Corie Drake, Mason Ide
  • Patent number: 8879797
    Abstract: An imaging flow cytometry system and method which includes a flow chamber, fluorescence analysis and imaging optics, image capturing system, device to regulate fluid flow through the chamber, and backlighting generator. The flow cell is configured so as to enhance the fluorescence signal collection by the system with total internal reflections. The fluorescence collection optics are configured to enhance the collection of the fluorescence from the side of the flow cell and concentrate it on light detectors.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: November 4, 2014
    Assignee: Fluid Imaging Technologies, Inc.
    Inventors: Christian K. Sieracki, Kent A. Peterson, Matthew A. Duplisea, Corie F. Drake
  • Patent number: 8345239
    Abstract: An imaging system with an imaging mechanism which includes polarization analyzers, which may be crossed polarization analyzers, positioned to provide birefringence images of particles in the fluid passing through the flow chamber. Captured images are of high resolution and may be used in comparison to known images of a library of images. The system and related method enhance the accuracy and sensitivity of particle monitoring by utilizing birefringence imaging combined with particle analysis and the detection of each particle's characteristic features, such as crystalline features. The system includes a scatter detector used to trigger backlighting of the flow chamber and capture images of particles therein.
    Type: Grant
    Filed: August 4, 2009
    Date of Patent: January 1, 2013
    Assignee: Fluid Imaging Technologies, Inc.
    Inventors: Christian K. Sieracki, William H. Nelson
  • Patent number: 7796256
    Abstract: A flow chamber, imaging objective, condenser and imaging light source as part of an optical system includes an oil-immersion objective and high numerical aperture condenser matched to a rectangular flow chamber. The oil-immersion objective and flow chamber include a high index of refraction immersion oil so as to enhance the optical resolution and optical coupling therethrough. The imaging light source generates light which passes through the condenser, the flow chamber and then the objective before being focused onto an imaging camera. Fluorescence excitation passes through the objective to the flow chamber where the oil immersion configuration enhances the focus and collection of the light back through the objective.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: September 14, 2010
    Assignee: Fluid Imaging Technologies, Inc.
    Inventors: Christian K. Sieracki, Kent A. Peterson
  • Publication number: 20090273774
    Abstract: A flow chamber, imaging objective, condenser and imaging light source as part of an optical system includes an oil-immersion objective and high numerical aperture condenser matched to a rectangular flow chamber. The oil-immersion objective and flow chamber include a high index of refraction immersion oil so as to enhance the optical resolution and optical coupling therethrough. The imaging light source generates light which passes through the condenser, the flow chamber and then the objective before being focused onto an imaging camera. Fluorescence excitation passes through the objective to the flow chamber where the oil immersion configuration enhances the focus and collection of the light back through the objective.
    Type: Application
    Filed: May 5, 2008
    Publication date: November 5, 2009
    Applicant: Fluid Imaging Technologies, Inc.
    Inventors: Christian K. Sieracki, Kent A. Peterson