Abstract: The invention provides a perfusion stock composition, for preserving a donor organ for transplantation, comprising: a source of 60 to 100 mM Na+; a source of 10 to 20 mM K+; a source of 5 to 10 mM Mg2+; a source of 0.25 to 0.75 mM Ca 2+; 10 to 40 mM Tris(hydroxymethyl)aminomethane hydrochloride (Tris or THAM), 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), 3-(N-morpholino)propanesulfonic acid (MOPS), 2-(N-mo:rpholino)ethanesulfonic acid (IviES), NjN-bis-(2-hy-droxyethyl)-2-aminoethansulfonic acid (BES), or N/-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid (TES); a source of 10 to 30 mM HC03?; 1 to 30 mM glucose; 1 to 20 U/L insulin; 1 to 10 mM fructose diphosphate or a salt thereof; 1 to 40 mM aspartate or glutamate; 1 to 10 mM adenosine, cAMP or cGMP; 1 to 10 mM reduced glutathione; and 30 to 100 mM lactobionate or mamlitol; and optionally a diluent.

Abstract: A gas-liquid separator system that can effectively and efficiently separate liquid from a streaming mixture having a liquid portion and a gas portion. The gas-liquid separator may be used in supercritical fluid chromatography application where an analyte is separated from a carrier gas, such as carbon dioxide. A streaming mixture is dispensed into a separation chamber formed by a spindle shaft configured inside of a shroud cavity. The shroud cavity has a plurality of concave channels along the inner surface and extend down to an outlet end. The concave channels create pressure variations that promote the liquid portion to condense onto the inner surface of the shroud and flow down to the exhaust port. A spherical collection portion is configured on the outlet of the shroud and the condensed liquid flows thereover and down along a cone portion and off the cone tip.

Abstract: A chromatography system has a cartridge adapter that is detachably attachable to enable a chromatography cartridge to be quickly interchanged. Chromatography cartridges are configured with threads for coupling to a corresponding interchangeable coupling component having matching threads. The interchangeable coupling component may be secured to the chromatography system by a coupling retainer. A coupling retainer may have a keyway that is configured for quick interchanging of the interchangeable coupling components. The interchangeable coupling component may have a pair of parallel sides that align with a slot of the keyway to secure the interchangeable coupling components to the coupling retainer. An inlet nipple of the chromatography cartridge may extend through an opening in the coupling components and couple to an inlet conduit for sample gas. Analyte gas may flow back to the chromatography system for detection and collection.

Abstract: Provided is a chiller and system that may be utilized in a supercritical fluid chromatography method, wherein a non-polar solvent may replace a portion or all of a polar solvent for the purpose of separating or extracting desired sample molecules from a combined sample/solvent stream. The system may reduce the amount of polar solvent necessary for chromatographic separation and/or extraction of desired samples. The system may incorporate a supercritical fluid chiller, a supercritical fluid pressure-equalizing vessel and a supercritical fluid cyclonic separator. The supercritical fluid chiller allows for efficient and consistent pumping of liquid-phase gases employing off-the-shelf HPLC pumps. The pressure equalizing vessel allows the use of off-the-shelf HPLC column cartridges. The system may further incorporate the use of one or more disposable cartridges containing silica gel or other suitable medium.

Abstract: A system includes a material sensor system having an inlet and an outlet. The inlet receives a flow of a material and the outlet outputs the flow of the material. The material sensor system includes an inner cavity having a surface, where the inner cavity receives the flow of the material. The material sensor system also includes a float system having one or more floats, where the one or more floats float within the material of the inner cavity. The material sensor system also includes a switch that sends one or more signals to a control valve system when the float system engages the surface of the inner cavity.

Abstract: Provided is a chiller and system that may be utilized in a supercritical fluid chromatography method, wherein a non-polar solvent may replace a portion or all of a polar solvent for the purpose of separating or extracting desired sample molecules from a combined sample/solvent stream. The system may reduce the amount of polar solvent necessary for chromatographic separation and/or extraction of desired samples. The system may incorporate a supercritical fluid chiller, a supercritical fluid pressure-equalizing vessel and a supercritical fluid cyclonic separator. The supercritical fluid chiller allows for efficient and consistent pumping of liquid-phase gases employing off-the-shelf HPLC pumps. The pressure equalizing vessel allows the use of off-the-shelf HPLC column cartridges. The system may further incorporate the use of one or more disposable cartridges containing silica gel or other suitable medium.

Abstract: Viscosity and other properties are determined at desired temperatures in drilling mud and other fluids by using a versatile cavitation device which, operating in the cavitation mode, mixes and heats the fluid to a specified temperature, and, operating in the shear mode, acts as a spindle for application of Couette principles to determine viscosity as a function of shear stress and shear rate. The invention obviates the practice of adjusting rheology of a drilling fluid by passing it through the drill bit. Drilling fluid may be managed by a “straight-through” method to the well, or by placing the cavitation device in a loop which isolates an aliquot of known volume and circulating the fluid through the loop including the cavitation device.

Abstract: Viscosity and other properties are determined at desired temperatures in drilling mud and other fluids by using a versatile cavitation device which, operating in the cavitation mode, mixes and heats the fluid to a specified temperature, and, operating in the shear mode, acts as a spindle for application of Couette principles to determine viscosity as a function of shear stress and shear rate. The invention obviates the practice of adjusting rheology of a drilling fluid by passing it through the drill bit. Drilling fluid may be managed by a “straight-through” method to the well, or by placing the cavitation device in a loop which isolates an aliquot of known volume and circulating the fluid through the loop including the cavitation device.

Abstract: Viscosity and other properties are determined at desired temperatures in drilling mud and other fluids by using a versatile cavitation device which, operating in the cavitation mode, mixes and heats the fluid to a specified temperature, and, operating in the shear mode, acts as a spindle for application of Couette principles to determine viscosity as a function of shear stress and shear rate. The invention obviates the practice of adjusting rheology of a drilling fluid by passing it through the drill bit. Drilling fluid may be managed by a “straight-through” method to the well, or by placing the cavitation device in a loop which isolates an aliquot of known volume and circulating the fluid through the loop including the cavitation device.

Abstract: A very light weight, noncompressible drilling fluid including a very light weight hydrocarbon base liquid, and a styrenic butadiene diblock copolymer is heated to achieve excellent rheology including thixotropicity, making an effective drilling fluid with a density of 8 pounds per gallon or less. Densities as low as 4 pounds per gallon are achieved with the addition of glass bubbles. The glass bubbles may, but normally will not, exceed 50% by volume. A method of making the drilling fluid includes passing the light weight liquid and the copolymer through a cavitation device. The invention includes drilling and with and recirculating the fluid to maintain the desired density, viscosity and rheology by adjusting the ingredients accordingly. A method of managed pressure drilling employs the novel fluid, enabling control of drill pressure and physical properties of the fluid including equivalent circulating density.

Abstract: A very light weight, noncompressible drilling fluid including a very light weight hydrocarbon base liquid, and a styrenic butadiene diblock copolymer is heated to achieve excellent rheology including thixotropicity, making an effective drilling fluid with a density of 8 pounds per gallon or less. Densities as low as 4 pounds per gallon are achieved with the addition of glass bubbles. The glass bubbles may, but normally will not, exceed 50% by volume. A method of making the drilling fluid includes passing the light weight liquid and the copolymer through a cavitation device. The invention includes drilling and with and recirculating the fluid to maintain the desired density, viscosity and rheology by adjusting the ingredients accordingly. A method of managed pressure drilling employs the novel fluid, enabling control of drill pressure and physical properties of the fluid including equivalent circulating density.

Abstract: Heavy fluids are made from calcium bromide and at least one hydrogen bond donor such as a low molecular weight polyol or an organic acid. The combination of a hydrogen bond donor and calcium bromide as a hydrogen bond acceptor in an appropriate molar ratio forms a higher density clear completion fluid at a low temperature not otherwise obtainable with heavy aqueous solutions of calcium bromide such as are used in oilfield wells. A method of making the fluid comprises mixing calcium bromide with the polyol(s) in the presence of water and then reducing the water content, thus forming a heavy fluid. A crystallization inhibitor such as nitrilotriacetamide or a particulate silicate is included in the formulation. When the heavy fluid “freezes,” its physical form is somewhat amorphous and pumpable rather than crystalline. The heavy fluid is useful as a drilling fluid as well as a completion fluid and for other purposes in oil recovery processes where extreme density is beneficial.

Abstract: A fluid delivery system includes a status indicator and control system comprising a processor. The processor is configured to receive a first signal indicative of a first status of operations of a spray application system. The processor is further configured to provide to an operator of a spray gun, via a display system, a visualization representative of the first status of operations, and techniques to control the fluid delivery system, wherein the spray application system is configured to deliver at least one fluid to the spray gun during operations.

Abstract: A spray system includes a spray applicator configured to apply a fluid to a target. The spray system also includes a rotary bell cup of the spray applicator, a splash plate of the spray applicator coupled to the rotary bell cup, and a fluid tip of the spray applicator. The fluid tip is configured to output the fluid onto the rotary bell cup. The fluid tip includes a fluid tip passage extending along a longitudinal fluid tip axis of the fluid tip. The longitudinal fluid tip axis intersects with the splash plate of the spray applicator. The fluid tip also includes a fluid exit port configured to output the fluid from the fluid tip passage onto the rotary bell cup. The fluid exit port extends along a fluid exit axis disposed at an angle relative to the longitudinal fluid tip axis of the fluid tip.

Abstract: A method for applying material to a bicycle frame includes determining, via a controller, at least one physical dimension of the bicycle frame. The method also includes determining, via the controller, a distance setting between at least two material applicators. In addition, the method includes determining, via the controller, a pattern size of material sprayed onto the bicycle frame by each of the at least two material applicators. Further, the method includes adjusting, via the controller, a position setting of the at least two material applicators based at least in part on the distance setting and pattern size. Moreover, the method includes applying, via the controller, material onto the bicycle frame through the at least two material applicators.

Abstract: A method includes receiving, via a processor, a unit configuration for a fluid mixing and dispensing system, where the unit configuration includes one or more fluid hardware components. The method also includes determining one or more software modules corresponding to the one or more fluid hardware components and configuring a modular plural component platform by loading the one or more software modules corresponding to the one or more fluid hardware components.

Abstract: A system includes an agitation system having a container configured to store a coating material, an agitator configured to agitate the coating material, and a sensor configured to sense conditions within the container and transmit the conditions. The system also includes an agitation control system having a controller configured to turn on the agitator, and change an intensity of agitation in response to an input received from the agitation system.

Abstract: A system having a material sensor system coupled to a material tank is provided. The material tank is configured to receive a quantity of the material and output a flow of the material. The material sensor system includes a float system coupled to an inner surface of the material tank. The float system includes a float configured float within a float cavity. The material sensor system includes a switch coupled to an outer surface of the material tank. The switch is communicatively coupled to the float system through a wall of the material tank, and the switch is configured to send one or more signals to a control system when the float engages the switch.

Abstract: An improved cavitation mixing and heating device employs an inlet directed toward the vertex of a conical or similar flow-directing element. The flow patterns of the fluid material to be mixed and heated are designed to preheat, spread, and create turbulent flow mixing of the fluid before it enters the cavitation zone, using heat generated in the cavitation zone that is conducted through the body of the cavitation rotor. The functions of the axially oriented inlet and flow directing element are assisted by a cantilever construction to alleviate stress on the bearings.

Abstract: A cavitation device is supplied by a disc pump with fluids for mixing. A cavitation rotor, having an array of cavities on its cylindrical surface, is fixed to a shaft for rotation by a motor. The disc pump and the cavitation device are beneficially in the same housing. At least one disc is spaced from and attached to the rotor near the inlet end of the cylindrical housing, so it will rotate with the rotor. A central hole in the (at least one) disc permits fluid to enter the space between the disc and the rotor; it is flung toward the peripheral space between the rotor and the cylindrical housing, where it is subjected to cavitation, and then passed to an outlet. The shaft may pass through one or both of the end walls of the cylindrical housing. The cavitation pump is especially useful for mixing oil field fluids.