Patents Assigned to FLUOGUIDE A/S
  • COMPOSITION COMPRISING A FLUOROPHORE LABELLED UPAR-TARGETING PEPTIDE CONJUGATE
    Publication number: 20230117827
    Abstract: The present invention describes a composition comprising a fluorophore labelled uPAR-targeting component, a buffer and a surfactant, wherein the fluorophore labelled uPAR-targeting component is solubilized in the composition by means of the surfactant being present, and wherein the composition comprises a maximum of 10 wt % water, preferably a maximum of 5 wt % water.
    Type: Application
    Filed: January 15, 2021
    Publication date: April 20, 2023
    Applicant: FLUOGUIDE A/S
    Inventors: Grethe Nørskov Rasmussen, Andreas Kjær, Morten Albrechtsen, Line Hartvig
  • uPAR targeting peptide for use in peroperative optical imaging of invasive cancer
    Publication number: 20210138090
    Abstract: There is provided a novel conjugate that binds to the cell surface receptor uPA (uPAR). The conjugate is based on a fluorescence-labeled peptide useful as a diagnostic probe to the surfaces of cells expressing uPAR. The conjugate is capable of carrying a suitable detectable and imageable label that will allow qualitative detection and also quantitation of uPAR levels in vitro and in vivo. This renders the surgical resection of tumors more optimal.
    Type: Application
    Filed: January 15, 2021
    Publication date: May 13, 2021
    Applicant: FLUOGUIDE A/S
    Inventors: Andreas KJAER, Morten PERSSON, Karina JUHL, Sorel KURBEGOVIC, Michael PLOUG, Knud Jørgen JENSEN, Kasper Kildegaard SØRENSEN, Anders CHRISTENSEN, Line HARTVIG, Grethe Nørskov RASMUSSEN, Morten ALBRECHTSEN