Patents Assigned to FOB Synthesis, Inc.
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Patent number: 10933051Abstract: The present invention provides carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections, including drug resistant or multiple-drug resistant bacterial infections, and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.Type: GrantFiled: June 11, 2018Date of Patent: March 2, 2021Assignee: FOB Synthesis, Inc.Inventors: Woo-Baeg Choi, Takashi Tomioka, Hyung-Yeul Joo, Phong Truong, Brian Min
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Patent number: 9937151Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.Type: GrantFiled: April 22, 2015Date of Patent: April 10, 2018Assignee: FOB Synthesis, Inc.Inventors: Woo-Baeg Choi, Ewa Gruszecka-Kowalik, Hyung-Yeul Joo, Shuangpei Liu, Shuli Mao, Yongfeng Li, Deog-Il Kim
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Patent number: 9149461Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.Type: GrantFiled: December 13, 2012Date of Patent: October 6, 2015Assignee: FOB Synthesis, Inc.Inventors: Woo-Baeg Choi, Ewa Gruszecka-Kowalik, Hyung-Yeul Joo, Shuangpei Liu, Shuli Mao, Yongfeng Li, Deog-Il Kim
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Patent number: 8557979Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of ?-methyl carbapenems which are useful as antibacterial agents.Type: GrantFiled: July 27, 2012Date of Patent: October 15, 2013Assignee: FOB Synthesis, Inc.Inventors: Woo-Baeg Choi, Ewa Kowalik
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Publication number: 20130172313Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.Type: ApplicationFiled: December 13, 2012Publication date: July 4, 2013Applicant: FOB SYNTHESIS, INC.Inventor: FOB Synthesis, Inc.
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Publication number: 20120296084Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of ?-methyl carbapenems which are useful as antibacterial agents.Type: ApplicationFiled: July 27, 2012Publication date: November 22, 2012Applicant: FOB Synthesis, Inc.Inventors: Woo-Baeg Choi, Ewa Kowalik
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Patent number: 8232268Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of ?-methyl carbapenems which are useful as antibacterial agents.Type: GrantFiled: February 15, 2010Date of Patent: July 31, 2012Assignee: FOB Synthesis, Inc.Inventors: Woo-Baeg Choi, Ewa Kowalik
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Publication number: 20100160284Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of ?-methyl carbapenems which are useful as antibacterial agents.Type: ApplicationFiled: February 15, 2010Publication date: June 24, 2010Applicant: FOB Synthesis, Inc.,Inventors: Woo-Baeg Choi, Ewa Kowalk
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Patent number: 7683049Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions, wherein the compounds are generally of the Formulae The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.Type: GrantFiled: June 10, 2005Date of Patent: March 23, 2010Assignee: FOB Synthesis, Inc.Inventors: Woo-Baeg Choi, Ewa Kowalik
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Patent number: 7632828Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions, wherein the compounds are generally of the Formulae The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of ΓΏ-methyl carbapenems which are useful as antibacterial agents.Type: GrantFiled: June 10, 2005Date of Patent: December 15, 2009Assignee: FOB Synthesis, Inc.Inventors: Woo-Baeg Choi, David S. Menaldino, Deog-Il Kim, Martin Bouygues, Michael W. Hager