Patents Assigned to FOB Synthesis, Inc.
  • Carbapenem compounds and compositions for the treatment of bacterial infections
    Patent number: 10933051
    Abstract: The present invention provides carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections, including drug resistant or multiple-drug resistant bacterial infections, and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.
    Type: Grant
    Filed: June 11, 2018
    Date of Patent: March 2, 2021
    Assignee: FOB Synthesis, Inc.
    Inventors: Woo-Baeg Choi, Takashi Tomioka, Hyung-Yeul Joo, Phong Truong, Brian Min
  • Carbapenem antibacterials with gram-negative activity
    Patent number: 9937151
    Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.
    Type: Grant
    Filed: April 22, 2015
    Date of Patent: April 10, 2018
    Assignee: FOB Synthesis, Inc.
    Inventors: Woo-Baeg Choi, Ewa Gruszecka-Kowalik, Hyung-Yeul Joo, Shuangpei Liu, Shuli Mao, Yongfeng Li, Deog-Il Kim
  • Carbapenem antibacterials with gram-negative activity
    Patent number: 9149461
    Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.
    Type: Grant
    Filed: December 13, 2012
    Date of Patent: October 6, 2015
    Assignee: FOB Synthesis, Inc.
    Inventors: Woo-Baeg Choi, Ewa Gruszecka-Kowalik, Hyung-Yeul Joo, Shuangpei Liu, Shuli Mao, Yongfeng Li, Deog-Il Kim
  • Carbapenem antibacterials with gram-negative activity and processes for their preparation
    Patent number: 8557979
    Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of ?-methyl carbapenems which are useful as antibacterial agents.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: October 15, 2013
    Assignee: FOB Synthesis, Inc.
    Inventors: Woo-Baeg Choi, Ewa Kowalik
  • Carbapenem Antibacterials with Gram-Negative Activity and Processes for Their Preparation
    Publication number: 20120296084
    Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of ?-methyl carbapenems which are useful as antibacterial agents.
    Type: Application
    Filed: July 27, 2012
    Publication date: November 22, 2012
    Applicant: FOB Synthesis, Inc.
    Inventors: Woo-Baeg Choi, Ewa Kowalik
  • Carbapenem antibacterials with gram-negative activity and processes for their preparation
    Patent number: 8232268
    Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of ?-methyl carbapenems which are useful as antibacterial agents.
    Type: Grant
    Filed: February 15, 2010
    Date of Patent: July 31, 2012
    Assignee: FOB Synthesis, Inc.
    Inventors: Woo-Baeg Choi, Ewa Kowalik
  • CARBAPENEM ANTIBACTERIALS WITH GRAM-NEGATIVE ACTIVITY AND PROCESSES FOR THEIR PREPARATION
    Publication number: 20100160284
    Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of ?-methyl carbapenems which are useful as antibacterial agents.
    Type: Application
    Filed: February 15, 2010
    Publication date: June 24, 2010
    Applicant: FOB Synthesis, Inc.,
    Inventors: Woo-Baeg Choi, Ewa Kowalk
  • Carbapenem antibacterials with gram-negative activity and processes for their preparation
    Patent number: 7683049
    Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions, wherein the compounds are generally of the Formulae The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.
    Type: Grant
    Filed: June 10, 2005
    Date of Patent: March 23, 2010
    Assignee: FOB Synthesis, Inc.
    Inventors: Woo-Baeg Choi, Ewa Kowalik
  • Gram-positive carbapenem antibacterials and processes for their preparation
    Patent number: 7632828
    Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions, wherein the compounds are generally of the Formulae The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of ΓΏ-methyl carbapenems which are useful as antibacterial agents.
    Type: Grant
    Filed: June 10, 2005
    Date of Patent: December 15, 2009
    Assignee: FOB Synthesis, Inc.
    Inventors: Woo-Baeg Choi, David S. Menaldino, Deog-Il Kim, Martin Bouygues, Michael W. Hager