Patents Assigned to Fochon Pharmaceuticals, Ltd.
  • Deuterated compounds as rock inhibitors
    Patent number: 11485707
    Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds thereof, and use of these compounds in preparing drugs for inhibiting ROCK.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: November 1, 2022
    Assignee: Fochon Pharmaceuticals, Ltd.
    Inventors: Rui Tan, Weipeng Zhang, Yunling Wang, Xingdong Zhao, Tao Cheng, Shu Lin, Weibo Wang
  • Sulfoximine, sulfonimidamide, sulfondiimine and diimidosulfonamide compounds as inhibitors of indoleamine 2,3-dioxygenase
    Patent number: 11168078
    Abstract: Provided are certain IDO inhibitors or pharmaceutically acceptable salts thereof which can inhibit enzymatic activity of indoleamine 2,3-dioxygenase (IDO) and may be useful for the treatment of diseases and disorders mediated by IDO. In addition, pharmaceutical compositions thereof and methods of use thereof are also provided.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: November 9, 2021
    Assignees: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Zhifang Chen, Rui Tan, Qihong Liu, Lijun Yang, Zhifu Li, Haohan Tan, Hongbin Liu, Xingdong Zhao, Min Lin, Jing Sun, Weibo Wang
  • Compounds as BLC-2-selective apoptosis-inducing agents
    Patent number: 11053239
    Abstract: Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof are provided. In particular, Bcl-2 inhibitors of formula (I) are provided, wherein the variable groups are as defined in the specification. The Bcl-2 inhibitors can be used to treat cell proliferative disorders.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: July 6, 2021
    Assignee: Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong Zhao, Zuwen Zhou, Chengxi He, Zhifu Li, Yue Rong, Rui Tan, Huajie Zhang, Hongbin Liu, Weipeng Zhang, Haohan Tan, Zhifang Chen, Lihua Jiang, Yanxin Liu, Min Lin, Jing Sun, Weibo Wang
  • MACROCYCLIC COMPOUNDS AS TRK KINASES INHIBITORS
    Publication number: 20210139506
    Abstract: Provided are certain TRK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: March 27, 2019
    Publication date: May 13, 2021
    Applicants: Fochon Pharmaceuticals, Ltd., Shanghai Fochon Pharmaceutical Co., LTD.
    Inventors: Huajie ZHANG, Qihong LIU, Chengxi HE, Weipeng ZHANG, Rui TAN, Bin LIU, Hong FU, Haohan TAN, Lijun YANG, Hongbin LIU, Yunling WANG, Yuwei GAO, Zongyao ZOU, Yanxin LIU, Shu LIN, Tongshuang LI, Xingdong ZHAO, Weibo WANG
  • Indolizine derivatives, composition and methods of use
    Patent number: 10894038
    Abstract: Provided are certain URAT1 inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
    Type: Grant
    Filed: December 26, 2016
    Date of Patent: January 19, 2021
    Assignees: SHANGHAI FOCHON PHARMACEUTICAL CO. LTD., FOCHON PHARMACEUTICALS, LTD.
    Inventors: Tongshuang Li, Xingdong Zhao, Chuiliang Yu, Haohan Tan, Xianlong Wang, Rui Tan, Bin Liu, Weipeng Zhang, Huajie Zhang, Qihong Liu, Zuwen Zhou, Zhifu Li, Yue Rong, Jing Sun, Weibo Wang
  • Certain protein kinase inhibitors
    Patent number: 10835535
    Abstract: Certain CDK4/6 inhibitors and pharmaceutically acceptable salts thereof are described. In particular, these compounds can inhibit kinase activity of CDK4/6 and may be useful for the treatment of hyper-proliferative diseases like cancer and inflammation. In addition, the pharmaceutical compositions thereof and methods of use thereof are also described.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: November 17, 2020
    Assignees: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong Zhao, Tongshuang Li, Zhifang Chen, Rui Tan, Ling Chen, Xianlong Wang, Lijun Yang, Zuwen Zhou, Yanxin Liu, Min Lin, Jing Sun, Weibo Wang
  • Substituted pyrrolo[2,3-d]pyridazin-4-ones and pyrazolo[3,4-d]pyridazin-4-ones as protein kinase inhibitors
    Patent number: 10800785
    Abstract: Provided are certain compounds or pharmaceutically acceptable salts thereof which can inhibit kinase activity of Bruton's tyrosine kinase (BTK) and may be useful for the treatment of diseases like cancer, immunological disease and inflammation.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: October 13, 2020
    Assignees: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong Zhao, Weipeng Zhang, Zhifang Chen, Ling Chen, Xianlong Wang, Zhifu Li, Rui Tan, Lijun Yang, Haohan Tan, Bin Liu, Kai Ran, Zongyao Zou, Min Lin, Jing Sun, Weibo Wang
  • COMPOUNDS AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS
    Publication number: 20190345156
    Abstract: Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof are provided. In particular, Bcl-2 inhibitors of formula (I) are provided, wherein the variable groups are as defined in the specification. The Bc1-2 inhibitors can be used to treat cell proliferative disorders.
    Type: Application
    Filed: January 5, 2018
    Publication date: November 14, 2019
    Applicants: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong ZHAO, Zuwen ZHOU, Chengxi HE, Zhifu LI, Yue RONG, Rui TAN, Huajie ZHANG, Hongbin LIU, Weipeng ZHANG, Haohan TAN, Zhifang CHEN, Lihua JIANG, Yanxin LIU, Min LIN, Jing SUN, Weibo WANG
  • SUBSTITUTED PYRROLO [2, 3-D] PYRIDAZIN-4-ONES AND PYRAZOLO [3, 4-D] PYRIDAZIN-4-ONES AS PROTEIN KINASE INHIBITORS
    Publication number: 20190161489
    Abstract: Provided are certain compounds or pharmaceutically acceptable salts thereof which can inhibit kinase activity of Bruton's tyrosine kinase (BTK) and may be useful for the treatment of diseases like cancer, immunological disease and inflammation.
    Type: Application
    Filed: June 20, 2017
    Publication date: May 30, 2019
    Applicants: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong ZHAO, Weipeng ZHANG, Zhifang CHEN, Ling CHEN, Xianlong WANG, Zhifu LI, Rui TAN, Lijun YANG, Haohan TAN, Bin LIU, Kai RAN, Zongyao ZOU, Min LIN, Jing SUN, Weibo WANG