Abstract: The invention provides low-molecular-weight over-sulfated polysaccharides with anti-heparanase activity prepared from marine native exopolysaccharides excreted by mesophilic marine bacteria from a deep-sea hydrothermal environment and relates to the use of these low-molecular-weight over-sulfated polysaccharides for the prevention or treatment of mucopolysaccharidoses, in particular mucopolysaccharidoses type III (Sanfilippo syndrome).
Type:
Application
Filed:
July 1, 2021
Publication date:
July 27, 2023
Applicants:
Institut Francais de Recherche Pour l'Exploitation de la Mer (IFREMER), Fondation Sanfilippo Suisse