Abstract: The present disclosure relates to a process for the preparation of core-shell particles by the coacervation method encapsulating contrast agents for multimodal imaging. The process consists in: a. Providing a water in oil emulsion of a biocompatible polyelectrolyte polymer. b. Providing an aqueous solution of a biocompatible polyelectrolyte polymer having opposite charges of the polyelectrolyte of step a). c. Adding a crosslinking agent to the primary emulsion and the secondary solution. d. Adding at least a tracer independently to the primary emulsion or the secondary solution or emulsion. e. Adding the secondary aqueous solution to the primary emulsions and occurring of the complex coacervation leading to the separation of the coacervate particles. f. Optionally absorb a further tracer into the nanoparticles The disclosure also relates to the coacervates obtained by the above described process and their use as probe for multimodal imaging in the diagnostic field.

Abstract: A multi-layered material with low thickness is provided, having properties of thermal and electric insulation, flame retardant capacity and high mechanical strength, useful for the manufacture of personal protective equipment and more in general of work items for the protection against arc flash effects. The material provides a high grade of protection against arc flash with good flexibility and comfort for the wearer, who is thus protected without being hindered in movements.