Abstract: The described invention relates to the use of the TAT-BH4 peptide for treating or preventing the progression of ALS. The methods include, postponing the appearance of symptoms and improving motor performance and survival in ALS. Methods are also provided, wherein the TAT-BH4 peptide is in a composition further comprising a pharmaceutically acceptable excipient.
Type:
Grant
Filed:
May 24, 2012
Date of Patent:
July 15, 2014
Assignee:
Fondazione Salvatore Maugeri Clinica del Lavora e Della Riabilitazione