Patents Assigned to Fonden til Fremme af Eksperimentel Cancerforskning
  • PAI-1 determination and use thereof
    Patent number: 6271352
    Abstract: a monoclonal antibody which binds a human endothelial type plasminogen activator inhibitor (PAI-1) produced by dexamethasone-treated human HT-1080 fibrosarcoma cells may be used, inter alia, for determining PAI-1 protein abundance in tumor tissue or a sample of a body fluid. Measurements of this parameter may be useful in predicting the presence or metastasis of a tumor, or of predicting the progression of a known malignant tumor.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: August 7, 2001
    Assignee: Fonden til Fremme af Eksperimentel Cancerforskning
    Inventors: Lars S. Nielsen, Peter Andreasen, Keld Dano, Nils Brunner