Patents Assigned to Food and Drug Administration
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Patent number: 11882837Abstract: Provided is a novel bacterial strain Bacteroides vulgatus MGM001 (Bacteroides vulgatus MGM001) and its use. The LPS from the strain of the subject matter has cytotoxicity weaker than the conventional ones and shows synergistic effect on the inhibition of biofilm formation when used in combination with LTA.Type: GrantFiled: September 20, 2019Date of Patent: January 30, 2024Assignees: SOGANG UNIVERSITY RESEARCH & BUSINESS DEVELOPMENT FOUNDATION, KOREA FOOD & DRUG ADMINISTRATIONInventors: Kyu-Ho Lee, Hyo-Sun Kwak, Youchul Jung, Kyung Jo Lee, Jeong-A Kim, Boram Jang, Sebin Kang
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Patent number: 11747333Abstract: The present invention relates to a method for detecting a target analyte using a gold nanoparticle, comprising growing a copper crystal specifically on a gold nanoparticle by treating the gold nanoparticle with a solution comprising a copper ion, a polymer having a primary or secondary amine group, and a reducing agent, a composition for amplifying a signal used in the detection method above, and a kit for detecting a target analyte comprising the composition for amplifying a signal above.Type: GrantFiled: February 14, 2018Date of Patent: September 5, 2023Assignees: KOREA FOOD & DRUG ADMINISTRATION, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATIONInventors: Jwa-Min Nam, Gwangpyo Ko, Jae-Ho Kim, Jeong-Eun Park, Mouhong Lin, In Sun Joo, Jeong Su Lee
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Publication number: 20230131334Abstract: The present disclosure relates to methods of predicting treatment sensitivity or drug resistance, especially for epidermal growth factor receptor (EGFR) inhibitors using leucine proline-enriched proteoglycan 1 (LEPRE1) gene expression level before or during a treatment, methods of discovering companion diagnostic biomarkers using efficacies of EGFR inhibitors on the expression of genes, including genes involved with regulation of extracellular matrix environment, or metabolism of collagen, and methods of predicting treatment sensitivity or resistance of drugs using the companion diagnostic biomarkers thereof.Type: ApplicationFiled: December 19, 2022Publication date: April 27, 2023Applicants: SYNTEKABIO, INC., KOREA FOOD & DRUG ADMINISTRATIONInventors: Jong Sun JUNG, Jong Gu LEE
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Patent number: 11441122Abstract: The present is directed to compositions comprising regulatory T cell epitopes, wherein said epitopes comprise a polypeptide comprising at least a portion of SEQ NOS: 1-14, fragments and/or variants thereof, as well as methods of producing and using the same.Type: GrantFiled: October 5, 2018Date of Patent: September 13, 2022Assignees: EpiVax Inc., The United States of America, as Represented by the Secretary, Department of Health and Human Services Food and Drug AdministrationInventors: William Martin, Amy S. Rosenberg
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Publication number: 20200163341Abstract: Provided is a novel bacterial strain Bacteroides vulgatus MGM001 (Bacteroides vulgatus MGM001) and its use. The LPS from the strain of the subject matter has cytotoxicity weaker than the conventional ones and shows synergistic effect on the inhibition of biofilm formation when used in combination with LTA.Type: ApplicationFiled: September 20, 2019Publication date: May 28, 2020Applicants: SOGANG UNIVERSITY RESEARCH & BUSINESS DEVELOPMENT FOUNDATION, KOREA FOOD & DRUG ADMINISTRATIONInventors: Kyu-Ho LEE, Hyo-Sun KWAK, Youchul JUNG, Kyung Jo LEE, Jeong-A KIM, Boram JANG, Sebin KANG
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Publication number: 20170252520Abstract: The present disclosure relates, according to some embodiments, to a puncture needle that can prevent the occurrence of coring. A puncture needle according to the present disclosure includes a cannula provided with a lumen. The cannula has a blade surface. The blade surface has: a sharp region located on a tip side of the blade surface and provided with a sharp edge on inner and outer circumferences of the blade surface; and a blunt region located on a base end side of the blade surface and provided with a blunt edge on the inner and outer circumferences of the blade surface. A tip of the blade surface is provided with a thick portion formed by a boundary between two surfaces, and the boundary forms an edge.Type: ApplicationFiled: March 2, 2016Publication date: September 7, 2017Applicants: NIPRO CORPORATION, Food and Drug AdministrationInventors: Yoshio Higaki, Oleg Vesnovsky
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Patent number: 9309515Abstract: Disclosed are a DNA aptamer specifically binding to the Her2 (ERBB2) receptor involved in the onset of breast cancer, a composition for the suppression of cancer metastasis comprising the same as an active ingredient, and a composition for the diagnosis of cancer comprising the same as an active ingredient. Due to its binding mechanism being different from that of the conventional antibody, the aptamer can be effectively used for suppressing cancer metastasis and diagnosing cancer.Type: GrantFiled: August 10, 2011Date of Patent: April 12, 2016Assignees: POSTECH ACADEMY-INDUSTRY FOUNDATION, KOREA FOOD & DRUG ADMINISTRATIONInventors: Jung Hwan Lee, Young Chan Chae, Youngdong Kim, Hyungu Kang, Jong Hun Im, Jong In Kim, Ki Seok Kim, Sung Key Jang, Il Ung Oh, Min Jeong Choi, Won Jun Kang
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Publication number: 20150005368Abstract: Disclosed are a DNA aptamer specifically binding to the Her2 (ERBB2) receptor involved in the onset of breast cancer, a composition for the suppression of cancer metastasis comprising the same as an active ingredient, and a composition for the diagnosis of cancer comprising the same as an active ingredient. Due to its binding mechanism being different from that of the conventional antibody, the aptamer can be effectively used for suppressing cancer metastasis and diagnosing cancer.Type: ApplicationFiled: August 10, 2011Publication date: January 1, 2015Applicants: KOREA FOOD & DRUG ADMINISTRATION, POSTECH ACADEMY-INDUSTRY FOUNDATIONInventors: Jung Hwan Lee, Young Chan Chae, Youndong Kim, Hyungu Kang, Jong Hun Im, Jong In Kim, Ki Seok Kim, Sung Key Jang, II Ung Oh, Min Jeong Choi, Won Jun Kang
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Publication number: 20130186695Abstract: Disclosed are a method and a system for estimating food commodity intakes.Type: ApplicationFiled: June 27, 2011Publication date: July 25, 2013Applicants: Korea Food & Drug Administration, Sejong University Industry Academy Cooperation Foundation, The Korea Health Industry Development InstituteInventors: Sang Hoon Ko, Seung Won Kim, Ki Sung Kwon, Jae Ho Oh, Jung Ah Do, Joong Keun Lee, Hee Dong Woo
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Publication number: 20090243856Abstract: Disclosed herein is a system for managing chemicals using Radio-Frequency Identification (RFID). A storage facility identification tag, attached to a chemical storage facility in a laboratory, stores the unique identification code of the chemical storage facility and a list of chemicals. A chemical identification tag, attached to the cover of a chemical container, stores the unique identification code of the chemical storage facility and chemical-related information. A mobile terminal, provided with an RFID reader, receives and outputs the unique identification code of the chemical storage facility, the list of the chemicals, and the chemical-related information.Type: ApplicationFiled: October 30, 2008Publication date: October 1, 2009Applicant: REPUBLIC OF KOREA (KOREA FOOD & DRUG ADMINISTRATION)Inventors: Sang Mok Lee, Kun Sang Park, Woo Sung Kim, Ho Il Kang, Chang Hee Lee, Dong Kil Lim, Yong Suk Ko, So Hee Kim, Dae Hyun Jo, Dai Byung Kim, Won Gon Yoo
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Publication number: 20090155412Abstract: Disclosed herein is a method of preparing trans fat-free oils and fats by an enzymatic interesterification (EI), and trans fat-free oils and fats prepared by the method. Specifically, the method comprises the steps of: 1) mixing fully hydrogenated fat derived from vegetable oil with RBD olive oil; 2) adding lipase to the mixed oil and reacting the mixed oil with lipase at 65 to 80° C. for 1 to 4 hours (1st reaction step); and 3) reacting the mixed oil from step 2) with the lipase at 40 to 60° C. for 44 to 47 hours (2nd reaction step).Type: ApplicationFiled: December 11, 2008Publication date: June 18, 2009Applicant: Republic of Korea (Management: Korea Food & Drug Administration)Inventors: In Hwan KIM, Sun Mi Lee, Bo Mi Lee, Ji Eun Oh, Myung Chul Kim, Hye Kyung Park, Jong Wook Kim, Kwang II Kwon, Jee Young Kim, Jee Sun Lee
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Patent number: 5196799Abstract: A method and apparatus for the non-destructive testing of a protective baer material. In a preferred embodiment, the method comprises applying an alternating electrical current across the protective barrier material for establishing a conductivity, G, of the protective barrier material and/or a quality factor, Q, of the protective barrier material. The conductivity, G, and/or the quality factor, Q, are measured at more than one frequency. The quality factor and/or conductivity measurements so obtained at the more than one frequency are compared to predetermined quality factor and/or conductivity limits.Type: GrantFiled: July 12, 1990Date of Patent: March 23, 1993Assignees: Drexel University, United States of America as represented by the Food & Drug AdministrationInventors: Richard B. Beard, Robert Schmukler, Herman P. Schwan, Frederick Prout