Patents Assigned to Forbes Medi-Tech Inc.
  • Publication number: 20100098755
    Abstract: A method of producing a tablet which comprises sterols and stanols includes the steps of forming the sterols and/or stanols, separately or together, into spherically-shaped, substantially uniform beads or prills and directly compressing the beads or prills into a tablet core.
    Type: Application
    Filed: October 22, 2008
    Publication date: April 22, 2010
    Applicant: FORBES MEDI-TECH INC.
    Inventor: Daniel Debeyer
  • Patent number: 7645749
    Abstract: Sterol and stanol nitro derivatives and their use in treating or preventing cardiovascular disease, its underlying conditions and other disorders are disclosed. The disclosed nitro derivatives are synthesized by ester linkage of a nitric oxide (NO)-releasing moiety to a sterol or stanol compound.
    Type: Grant
    Filed: April 3, 2006
    Date of Patent: January 12, 2010
    Assignee: Forbes Medi-Tech Inc.
    Inventors: Patricia Liliana Orchansky, James P. Kutney
  • Patent number: 7645748
    Abstract: Sterol and stanol phosphorylnitro derivatives and their use in treating or preventing cardiovascular disease, its underlying conditions and other disorders are disclosed. The disclosed compounds include a phosphate linker, at least one moiety that releases nitric oxide (NO), and a sterol or stanol moiety. Some compounds additionally include an ascorbyl moiety to make the compound more readily soluble in aqueous and non-aqueous media.
    Type: Grant
    Filed: April 3, 2006
    Date of Patent: January 12, 2010
    Assignee: Forbes Medi-Tech Inc.
    Inventors: Patricia Liliana Orchansky, James P. Kutney
  • Publication number: 20070254088
    Abstract: A composition comprises one or more free (unesterified) phytosterols and/or phytostanols which are substantially completely dissolved in one or more esterified phytosterols and/or phytostanols. The present invention further provides a composition comprising one or more esterified phytosterols and/or phytostanols which are substantially completely dissolved in an edible oil.
    Type: Application
    Filed: May 1, 2007
    Publication date: November 1, 2007
    Applicant: FORBES MEDI-TECH INC.
    Inventors: David John Stewart, Jerzy Zawistowski, Miruna Laza
  • Publication number: 20070254026
    Abstract: A composition for use in softgel capsules comprises one or more esters of phytosterols and/or phytostanols which have been treated to enhance their flowability at ambient temperatures prior to or concurrent with softgel formation.
    Type: Application
    Filed: May 1, 2007
    Publication date: November 1, 2007
    Applicant: FORBES MEDI-TECH INC.
    Inventor: David John Stewart
  • Publication number: 20070141123
    Abstract: A stable emulsion in which an aqueous phase has one or more phytosterols or phytostanols, or mixtures thereof in free (non-esterified) form and an oil or fat phase has phytosterols or phytostanols, or mixtures thereof, in esterified form.
    Type: Application
    Filed: December 20, 2006
    Publication date: June 21, 2007
    Applicant: FORBES MEDI-TECH INC.
    Inventor: Jerzy Zawistowski
  • Publication number: 20070141224
    Abstract: A composition for use in foods, beverages and nutraceuticals that includes one or more non-sterol emulsifiers, each having an HLB value of greater than 14 and one or more sterols or stanols or mixtures thereof.
    Type: Application
    Filed: December 20, 2006
    Publication date: June 21, 2007
    Applicant: FORBES MEDI-TECH INC.
    Inventor: Jerzy Zawistowski
  • Publication number: 20040236125
    Abstract: The present invention provides, in one aspect, novel derivatives comprising sterols and/or stanols and an NSAID selected from salicylic acids and arylalkanoic acids, including salts of these derivatives, and having one or more of the following formulae: 1
    Type: Application
    Filed: September 25, 2002
    Publication date: November 25, 2004
    Applicant: FORBES MEDI-TECH INC.
    Inventors: James P. Kutney, P. Haydn Pritchard, Yanbing Ding, Kishor M. Wasan
  • Publication number: 20030232797
    Abstract: The present invention provides novel derivatives comprising compounds in the androstane and androstene series, coupled with ascorbic acid, including salts thereof, and represented by one or more of the general formulae: 1
    Type: Application
    Filed: June 6, 2002
    Publication date: December 18, 2003
    Applicant: FORBES MEDI-TECH INC.
    Inventors: James P. Kutney, Hongming Chen, Duanjie Hou, Changqing Wang
  • Publication number: 20030144536
    Abstract: A process for isolating and purifying phytosterols and phytostanols from tall oil pitch is disclosed which comprises the following steps:
    Type: Application
    Filed: January 28, 2002
    Publication date: July 31, 2003
    Applicant: Forbes Medi-Tech Inc.
    Inventors: William E. Sonnier, Michael E. Schultz
  • Publication number: 20020156051
    Abstract: Novel phytosterol and/or phytostanol derivatives, including salts thereof, are represented by the general formulae: 1
    Type: Application
    Filed: July 25, 2001
    Publication date: October 24, 2002
    Applicant: FORBES MEDI-TECH INC.
    Inventors: James P. Kutney, Radka K. Milanova, Yangbing Ding, Hongming Chen, Duanjie Hou
  • Patent number: 6087353
    Abstract: The present invention provides a esterified and subsequently hydrogenated phytosterol composition for use alone or for incorporation into foods, beverages, pharmaceuticals, nutraceuticals, and the like. The composition has the advantage of enhanced solubility/dispersability, increased molar potency and enhanced stability over naturally isolated phytosterol compositions. Methods for the esterification and subsequent hydrogenation of the phytosterols are also provided.
    Type: Grant
    Filed: May 15, 1998
    Date of Patent: July 11, 2000
    Assignee: Forbes Medi-Tech Inc.
    Inventors: David John Stewart, Radka Milanova, Jerzy Zawistowski, Simon Howard Wallis
  • Patent number: 6071714
    Abstract: A novel process for the fermentation of phytosterol compositions to androstenedione (androst-4-ene-3,17-dione, AD) and/or androstadienedione (androsta-1,4-diene-3,17-dione, ADD) is disclosed. The process utilizes the micro-organism Mycobacterium MB 3683, and selected suitable solubilizing agents such as polypropylene glycol or silicone for solubilizing the phytosterol compositions at high concentrations in the nutrient medium. The innoculum of Mycobacterium MB 3683 is grown in a nutrient medium comprising Refiners molasses and inorganic salts.
    Type: Grant
    Filed: March 26, 1998
    Date of Patent: June 6, 2000
    Assignee: Forbes Medi-Tech, Inc.
    Inventors: James P. Kutney, Radka K. Milanova, Christo Dimitrov Vassilev, Svetoslav Stefanov Stefanov, Natalya Velikova Nedelcheva
  • Patent number: 5985936
    Abstract: A method of preventing and/or delaying the onset of Alzheimer's disease in an animal comprises administering to the animal a phytosterol composition. A composition useful for preventing and/or delaying the onset of Alzheimer's disease in an animal comprises a phytosterol composition.
    Type: Grant
    Filed: December 18, 1997
    Date of Patent: November 16, 1999
    Assignee: Forbes Medi-Tech, Inc.
    Inventor: Egon Novak
  • Patent number: 5965449
    Abstract: Methods are provided for determining whether a subject animal has an increased risk of cardiovascular or related disorder. The level of serum campesterol and beta-sitosterol are determined and a campesterol/beta-sitosterol ratio obtained. The ratio determined for the subject animal is compared with that of a normal control animal and correlated with the risk of cardiovascular or a related disorder.
    Type: Grant
    Filed: July 3, 1996
    Date of Patent: October 12, 1999
    Assignee: Forbes Medi-Tech, Inc.
    Inventor: Egon Novak