Patents Assigned to Fordham University
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Patent number: 11879176Abstract: The present disclosure is concerned with metal oxide nanowires, and more specifically, to crystalline ruthenium oxide (RuO2) nanowires, sol-gel synthetic methods for preparing the nanowires, and methods of using the nanowires in metal catalyzed oxidation of small organic molecules.Type: GrantFiled: January 10, 2020Date of Patent: January 23, 2024Assignee: FORDHAM UNIVERSITYInventors: Christopher Koenigsmann, Alexander Charles Santulli
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Publication number: 20140030628Abstract: The invention provides a novel fuel cell, the output voltage of which is pH dependent. The fuel cell comprises a membrane electrode assembly and a light source. In accordance with one embodiment, the membrane electrode assembly includes i) an electrolyte; ii) an anode operably coupled to the electrolyte; and iii) a cathode operably coupled to the electrolyte, wherein the cathode is made from an electrically conductive material and has an unroughened surface where an adsorbate material is applied. The adsorbate material used herein comprises a material having semiconductor properties, and the combination of the electrically conductive material and the adsorbate material is photosensitive and has catalytic properties. The invention also provides a novel electrode that can be used as a cathode in a fuel cell, a novel method for making the electrode, and a novel method of generating electricity using the fuel cell and/or electrode of the invention.Type: ApplicationFiled: July 25, 2013Publication date: January 30, 2014Applicant: FORDHAM UNIVERSITYInventor: John J. McMahon
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Patent number: 8349757Abstract: The invention provides an electrode comprising an electrically conductive material having a surface capable of producing surface enhanced Raman scattering of incident light from a complex adsorbed at the surface of the electrode, the complex including the electrically conductive material combined with a second material that is substantially reducible and not substantially oxidizable. The surface of the electrode can be microroughened. The invention also includes a method for making various embodiments of the electrode, and a method of generating electricity using the electrode. In accordance with a further aspect of the invention, a fuel cell is provided including the electrode of the invention.Type: GrantFiled: March 14, 2011Date of Patent: January 8, 2013Assignee: Fordham UniversityInventor: John J. McMahon
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Patent number: 7906450Abstract: The invention provides an electrode comprising an electrically conductive material having a surface capable of producing surface enhanced Raman scattering of incident light from a complex adsorbed at the surface of the electrode, the complex including the electrically conductive material combined with a second material that is substantially reducible and not substantially oxidizable. The surface of the electrode can be microroughened. The invention also includes a method for making various embodiments of the electrode, and a method of generating electricity using the electrode. In accordance with a further aspect of the invention, a fuel cell is provided including the electrode of the invention.Type: GrantFiled: March 8, 2010Date of Patent: March 15, 2011Assignee: Fordham UniversityInventor: John J. McMahon
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Patent number: 7696121Abstract: The invention provides an electrode comprising an electrically conductive material having a surface capable of producing surface enhanced Raman scattering of incident light from an adsorbate material adsorbed on the surface of the electrode. The adsorbate is substantially reducible and not substantially oxidizable. The surface of the electrode can be microroughened and include, for example, a plurality of adatoms or clusters of adatoms of a metallic material. The adatoms or clusters of adatoms form sites for photocatalysis of electroreduction when the electrode is irradiated with a light source. The invention also includes a method for making the electrode, and a method of generating electricity using the electrode. In accordance with a further aspect of the invention, a fuel cell is provided including the electrode of the invention.Type: GrantFiled: March 30, 2006Date of Patent: April 13, 2010Assignee: Fordham UniversityInventor: John J. McMahon
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Patent number: 7687424Abstract: The invention provides an electrode comprising an electrically conductive material having a surface capable of producing surface enhanced Raman scattering of incident light from a complex adsorbed at the surface of the electrode, the complex including the electrically conductive material combined with a second material that is substantially reducible and not substantially oxidizable. The surface of the electrode can be microroughened. The invention also includes a method for making various embodiments of the electrode, and a method of generating electricity using the electrode. In accordance with a further aspect of the invention, a fuel cell is provided including the electrode of the invention.Type: GrantFiled: June 28, 2007Date of Patent: March 30, 2010Assignee: Fordham UniversityInventor: John J. McMahon
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Patent number: 7601359Abstract: The present invention relates to methods and compositions for eliciting an immune response and the prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases. The methods of the invention comprise administering a composition comprising an effective amount of a complex, in which the complex consists essentially of a heat shock protein (hsp) noncovalently bound to an antigenic molecule. “Antigenic molecule” as used herein refers to the peptides with which the hsps are endogenously associated in vivo as well as exogenous antigens/immunogens (i.e., with which the hsps are not complexed in vivo) or antigenic/immunogenic fragments and derivatives thereof. In a preferred embodiment, the complex is autologous to the individual. The effective amounts of the complex are in the range of 10-600 micrograms for complexes comprising hsp70, 50-1000 micrograms for hsp90, and 10-600 micrograms for gp96.Type: GrantFiled: June 4, 1998Date of Patent: October 13, 2009Assignee: Fordham UniversityInventor: Pramod K. Srivastava
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Publication number: 20070292735Abstract: The invention provides an electrode comprising an electrically conductive material having a surface capable of producing surface enhanced Raman scattering of incident light from a complex adsorbed at the surface of the electrode, the complex including the electrically conductive material combined with a second material that is substantially reducible and not substantially oxidizable. The surface of the electrode can be microroughened. The invention also includes a method for making various embodiments of the electrode, and a method of generating electricity using the electrode. In accordance with a further aspect of the invention, a fuel cell is provided including the electrode of the invention.Type: ApplicationFiled: June 28, 2007Publication date: December 20, 2007Applicant: Fordham UniversityInventor: John McMahon
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Publication number: 20040047876Abstract: The present invention relates to methods and compositions for eliciting an immune response and the prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases. The methods of the invention comprise administering a composition comprising an effective amount of a complex, in which the complex consists essentially of a heat shock protein (hsp) noncovalently bound to an antigenic molecule. “Antigenic molecule” as used herein refers to the peptides with which the hsps are endogenously associated in vivo as well as exogenous antigens/immunogens (i.e., with which the hsps are not complexed in vivo) or antigenic/immunogenic fragments and is derivatives thereof. In a preferred embodiment, the complex is autologous to the individual. The effective amounts of the complex are in the range of 10-600 micrograms for complexes comprising hsp70, 50-1000 micrograms for hsp90, and 10-600 micrograms for gp96.Type: ApplicationFiled: August 12, 2003Publication date: March 11, 2004Applicant: Fordham University.Inventor: Pramod K. Srivastava
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Patent number: 6687012Abstract: The change in the circular birefringence of a sample is measured by passing a light beam comprised of a left circularly polarized (LCP) wave and a right circularly polarized (RCP) wave through a sample and measuring the change in the phase difference between the RCP and LCP waves.Type: GrantFiled: October 30, 2001Date of Patent: February 3, 2004Assignee: Fordham UniversityInventor: Martin Sanzari
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Publication number: 20030035808Abstract: The present invention relates to immunogenic complexes of heat shock proteins (hsp) noncovalently bound to exogenous antigenic molecules which when administered to an individual elicit specific immunological responses in the host. Methods of prevention and treatment of cancer and infectious disease are provided.Type: ApplicationFiled: October 7, 2002Publication date: February 20, 2003Applicant: Fordham UniversityInventor: Pramod K. Srivastava
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Publication number: 20030012793Abstract: The invention relates to methods and compositions for the promotion of tissue repair. Specifically, compositions comprising heat shock proteins, including gp96, hsp90, and hsp70, uncompleted or completed noncovalently with antigenic molecules, are disclosed. Therapeutic methods for administering the hsp-containing compositions are disclosed. The disclosed methods are useful for promoting repair of tissues that were disrupted by a variety of causes including trauma (e.g., surgery, injury or burns) or disease or disorder (e.g., atherosclerosis and multiple sclerosis).Type: ApplicationFiled: June 18, 2002Publication date: January 16, 2003Applicant: Fordham UniversityInventors: Pramod K. Srivastava, Rajiv Y. Chandawarkar
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Publication number: 20030012794Abstract: The present invention relates to methods and compositions for eliciting an immune response and the prevention-and treatment of primary and metastatic neoplastic diseases and infectious diseases. The methods of the invention comprise administering a composition comprising an effective amount of a complex, in which the complex consists essentially of a heat shock protein (hsp) noncovalently bound to an antigenic molecule. Optionally, the methods further comprise administering antigen presenting cells sensitized with complexes of hsps noncovalently bound to an antigenic molecule. “Antigenic molecule” as used herein refers to the peptides with which the hsps are endogenously associated in vivo as well as exogenous antigens/immunogens (i.e., with which the hsps are not complexed in vivo) or antigenic/immunogenic fragments and derivatives thereof. In a preferred embodiment, the complex is autologous to the individual. In a specific embodiment, the effective amounts of the complex are in the range of 0.Type: ApplicationFiled: August 2, 2002Publication date: January 16, 2003Applicant: Fordham UniversityInventors: Pramod K. Srivastava, Rajiv Y. Chandawarkar
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Patent number: 6475490Abstract: The invention relates to methods and compositions for the promotion of tissue repair. Specifically, compositions comprising heat shock proteins, including gp96, hsp90, and hsp70, uncomplexed or complexed noncovalently with antigenic molecules, are disclosed. Therapeutic methods for administering the hsp-containing compositions are disclosed. The disclosed methods are useful for promoting repair of tissues that were disrupted by a variety of causes including trauma (e.g., surgery, injury or burns) or disease or disorder (e.g., atherosclerosis and multiple sclerosis).Type: GrantFiled: October 19, 1998Date of Patent: November 5, 2002Assignee: Fordham UniversityInventors: Pramod K. Srivastava, Rajiv Y. Chandawarkar
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Patent number: 6461615Abstract: The present invention relates to immunogenic complexes of heat shock proteins (hsp) noncovalently bound to exogenous antigenic molecules which when administered to an individual elicit specific immunological responses in the host. Methods of prevention and treatment of cancer and infectious disease are provided.Type: GrantFiled: April 7, 2000Date of Patent: October 8, 2002Assignee: Fordham UniversityInventor: Pramod K. Srivastava
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Patent number: 6455048Abstract: The present invention relates to methods and compositions for eliciting an immune response and the prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases. The methods of the invention comprise administering a composition comprising an effective amount of a complex, in which the complex consists essentially of a heat shock protein (hsp) noncovalently bound to an antigenic molecule. Optionally, the methods further comprise administering antigen presenting cells sensitized with complexes of hsps noncovalently bound to an antigenic molecule. “Antigenic molecule” as used herein refers to the peptides with which the hsps are endogenously associated in vivo as well as exogenous antigens/immunogens (i.e., with which the hsps are not complexed in vivo) or antigenic/immunogenic fragments and derivatives thereof. In a preferred embodiment, the complex is autologous to the individual. In a specific embodiment, the effective amounts of the complex are in the range of 0.Type: GrantFiled: November 15, 1999Date of Patent: September 24, 2002Assignee: Fordham UniversityInventors: Pramod K. Srivastava, Rajiv Y. Chandawarkar
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Patent number: 6447780Abstract: The present invention relates to methods and compositions for eliciting an immune response and the prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases. The methods of the invention comprise administering a composition comprising an effective amount of a complex, in which the complex consists essentially of a heat shock protein (hsp) noncovalently bound to an antigenic molecule. Optionally, the methods further comprise administering antigen presenting cells sensitized with complexes of hsps noncovalently bound to an antigenic molecule. “Antigenic molecule” as used herein refers to the peptides with which the hsps are endogenously associated in vivo as well as exogenous antigens/immunogens (i.e., with which the hsps are not complexed in vivo) or antigenic/immunogenic fragments and derivatives thereof. In a preferred embodiment, the complex is autologous to the individual. In a specific embodiment; the effective amounts of the complex are in the range of 0.Type: GrantFiled: October 26, 1999Date of Patent: September 10, 2002Assignee: Fordham UniversityInventors: Pramod K. Srivastava, Rajiv Y. Chandawarkar
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Patent number: 6447781Abstract: The present invention relates to immunogenic complexes of heat shock proteins (hsp) noncovalently bound to exogenous antigenic molecules which when administered to an individual elicit specific immunological responses in the host. Methods of prevention and treatment of cancer and infectious disease are provided.Type: GrantFiled: April 7, 2000Date of Patent: September 10, 2002Assignee: Fordham UniversityInventor: Pramod K. Srivastava
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Patent number: 6436404Abstract: The present invention relates to methods and compositions for eliciting an immune response and the prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases. The methods of the invention comprise administering a composition comprising an effective amount of a complex, in which the complex consists essentially of a heat shock protein (hsp) noncovalently bound to an antigenic molecule. Optionally, the methods further comprise administering antigen presenting cells sensitized with complexes of hsps noncovalently bound to an antigenic molecule. “Antigenic molecule” as used herein refers to the peptides with which the hsps are endogenously associated in vivo as well as exogenous antigens/immunogens (i.e., with which the hsps are not complexed in vivo) or antigenic/immunogenic fragments and derivatives thereof. In a preferred embodiment, the complex is autologous to the individual. In a specific embodiment, the effective amounts of the complex are in the range of 0.Type: GrantFiled: November 15, 1999Date of Patent: August 20, 2002Assignee: Fordham UniversityInventors: Pramod K. Srivastava, Rajiv Y. Chandawarkar
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Patent number: 6410028Abstract: The present invention relates to immunogenic complexes of heat shock proteins (hsp) noncovalently bound to exogenous antigenic molecules which when administered to an individual elicit specific immunological responses in the host. Methods of prevention and treatment of cancer and infectious disease are provided.Type: GrantFiled: August 9, 1999Date of Patent: June 25, 2002Assignee: Fordham UniversityInventor: Pramod K. Srivastava