Abstract: This application discloses oral liquid formulations of lipid/cholesterol-lowering drugs and blood pressure-lowering drugs, and combinations thereof, comprising surfactant(s) as stabilizer(s), which forms micelles with the drug molecules to enhance their solubility and stability.
Abstract: The present invention relates to injectable microspheres and formulations comprising the microspheres for controlled release of progestogen hormones.
Abstract: Disclosed are injectable nanoparticle compositions comprising a micelle formulation of an antithrombotic agent and a water-soluble, biodegradable, and amphiphilic polymer that improves water solubility of the antithrombotic agent. A method of preparing the injectable nanoparticle compositions and methods for preventing or treating thrombotic diseases such as venous thromboembolisms and/or stroke using the compositions, as well as devices and kits suitable for such treatment, are also disclosed.
Abstract: Drug-loaded microspheres containing both a steroidal anti-inflammatory drug and a non-steroidal anti-inflammatory drug and injectable formulations containing the microspheres for sustained release of both drugs are disclosed. Methods of making such drug-loaded microspheres, formulations, and use of them for treating pains and inflammations, especially those caused by rheumatoid arthritis or osteoarthritis using such microspheres and formulations are also described.
Abstract: Disclosed herein are pharmaceutical formulations of aprepitant suitable for parenteral administration including intravenous administration. The pharmaceutical formulations are stable and ready-to-use liposomes for the treatment of emesis and are particularly useful for treatment of chemotherapy or surgery-induced nausea and vomiting. Methods of preparation of the aprepitant formulations are also provided.
Type:
Grant
Filed:
June 26, 2018
Date of Patent:
March 1, 2022
Assignee:
ForDoz Pharma Corp.
Inventors:
Sydney Ugwu, Xin He, Zengli Fu, Xin Teng, Ming Ji
Abstract: Disclosed herein are pharmaceutical formulations of aprepitant suitable for parenteral administration including intravenous administration. The pharmaceutical formulations are stable and ready-to-use liposomes for the treatment of emesis and are particularly useful for treatment of chemotherapy or surgery-induced nausea and vomiting. Methods of preparation of the aprepitant formulations are also provided.
Type:
Application
Filed:
June 26, 2018
Publication date:
May 7, 2020
Applicant:
ForDoz Pharma Corp.
Inventors:
Sydney Ugwu, Xin He, Zengli Fu, Xin Teng, Ming Ji