Abstract: Provided herein are heterocyclic derivative compounds of Formula (II), and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
Type:
Grant
Filed:
March 18, 2021
Date of Patent:
August 9, 2022
Assignee:
FORGE THERAPEUTICS, INC.
Inventors:
Min Teng, Baskar Nammalwar, Xiaoming Li, Christian Perez, Ian Yule, Adele Faulkner, Holly Atton, Alastair Parkes, Serge Convers-Reignier, Michelle Southey, David T. Puerta
Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
Type:
Grant
Filed:
May 9, 2018
Date of Patent:
June 1, 2021
Assignee:
FORGE THERAPEUTICS, INC.
Inventors:
Min Teng, Baskar Nammalwar, Konstantin Taganov, Xiaoming Li, David T. Puerta
Abstract: The present teachings relate to hydroxypyrimidinone derivatives of Formula II, pharmaceutical compositions thereof, and methods of using such compounds to treat bacterial infections.
Type:
Grant
Filed:
July 15, 2019
Date of Patent:
December 29, 2020
Assignee:
FORGE THERAPEUTICS, INC.
Inventors:
Min Teng, Baskar Nammalwar, Konstantin Taganov, David T. Puerta
Abstract: The present teachings relate to pyrone derivatives, pharmaceutical compositions thereof, and methods of using such compounds to treat bacterial infections.
Type:
Grant
Filed:
November 9, 2016
Date of Patent:
April 7, 2020
Assignee:
FORGE THERAPEUTICS, INC.
Inventors:
Min Teng, Baskar Nammalwar, Konstantin Taganov, David T. Puerta
Abstract: The present teachings relate to hydroxypyrimidinone derivatives of Formula IV, pharmaceutical compositions thereof, and methods of using such compounds to treat bacterial infections.
Type:
Grant
Filed:
November 9, 2016
Date of Patent:
September 17, 2019
Assignee:
FORGE THERAPEUTICS, INC.
Inventors:
Min Teng, Baskar Nammalwar, Konstantin Taganov, David T. Puerta