Abstract: This invention is a novel method for making zirconia ceramic from hybrid composite biomaterials. The inorganic particles of zirconium oxide with a desired size and controlled shape were synthesized in an alcohol solution in the presence of water and a morphologic catalyst. Zirconium alkoxides and/or zirconium oxychloride, Yttrium alkoxide, Yttrium nitrate hexahydrate and Yttrium chloride, were used as the precursor materials for the preparation of zirconium oxide colloidal suspensions. Particle surface modification by the introduction of polymerization precursors was carried out in colloidal suspension. Highly-filled and well dispersed composite biomaterials with thermoplastic and/or thermo-hardening matrices are easily obtained using several polymerization techniques, like catalytic polymerization, controlled free radical polymerization, and polycondensation.