Patents Assigned to FORMYCON AG
  • Patent number: 11666632
    Abstract: A pre-filled pharmaceutical package comprising a liquid formulation of a VEGF-antagonist, for example Ranibizumab, in a pre-filled pharmaceutical package, for example a syringe, cartridge, or vial, made in part or in whole of a thermoplastic polymer, coated on the interior with a tie coating or layer, a barrier coating or layer, a pH protective coating or layer, and optionally a lubricity coating or layer. Stability performance of the VEGF-antagonist packaged in the coated COP vessel comparable to or better than glass was obtained.
    Type: Grant
    Filed: February 26, 2022
    Date of Patent: June 6, 2023
    Assignees: FORMYCON AG, SIO2 MEDICAL PRODUCTS, INC., KLINGE BIOPHARMA GMBH
    Inventors: Carsten Brockmeyer, Christopher Weikart, Murray Stephen Bennett, Jean-Pierre Giraud, Thomas Strungmann
  • Publication number: 20220362441
    Abstract: The present invention relates to a pre-filled syringe containing a VEGF antagonist and comprising a plastic barrel which is silicone-free, kits comprising this syringe and the use of the syringe for the administration of a VEGF antagonist in the treatment of ocular diseases.
    Type: Application
    Filed: July 18, 2022
    Publication date: November 17, 2022
    Applicant: FORMYCON AG
    Inventor: Bernd FIEDLER
  • Patent number: 11298405
    Abstract: A pre-filled pharmaceutical package comprising a liquid formulation of a VEGF-antagonist, for example Ranibizumab, in a pre-filled pharmaceutical package, for example a syringe, cartridge, or vial, made in part or in whole of a thermoplastic polymer, coated on the interior with a tie coating or layer, a barrier coating or layer, a pH protective coating or layer, and optionally a lubricity coating or layer. Stability performance of the VEGF-antagonist packaged in the coated COP vessel comparable to or better than glass was obtained.
    Type: Grant
    Filed: January 21, 2021
    Date of Patent: April 12, 2022
    Assignees: FORMYCON AG, SIO2 MEDICAL PRODUCTS, INC., KLINGE BIOPHARMA GMBH
    Inventors: Carsten Brockmeyer, Christopher Weikart, Murray Stephen Bennett, Jean-Pierre Giraud, Thomas Strungmann
  • Patent number: 10576128
    Abstract: The present invention relates to liquid pharmaceutical compositions of a VEGF antagonist for intravitreal administration comprising a histidine buffer, an inorganic salt, a carbohydrate and a polysorbate.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: March 3, 2020
    Assignee: FORMYCON AG
    Inventor: Rainer Sigl
  • Patent number: 10568951
    Abstract: The present invention relates to liquid pharmaceutical formulations for intravitreal injection of an anti-VEGF antibody which does not contain saccharides for use in the treatment of age-related macular degeneration.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: February 25, 2020
    Assignee: FORMYCON AG
    Inventor: Rainer Sigl
  • Publication number: 20190030123
    Abstract: The present invention relates to liquid pharmaceutical compositions of a VEGF antagonist for intravitreal administration comprising a histidine buffer, an inorganic salt, a carbohydrate and a polysorbate.
    Type: Application
    Filed: January 26, 2017
    Publication date: January 31, 2019
    Applicant: FORMYCON AG
    Inventor: Rainer SIGL
  • Publication number: 20180326126
    Abstract: The present invention relates to a pre-filled syringe containing a VEGF antagonist and comprising a plastic barrel which is silicone-free, kits comprising this syringe and the use of the syringe for the administration of a VEGF antagonist in the treatment of ocular diseases.
    Type: Application
    Filed: November 18, 2016
    Publication date: November 15, 2018
    Applicant: FORMYCON AG
    Inventor: Bernd FIEDLER