Abstract: A method of producing 5-ketofructose using an acetic acid bacterium which is genetically modified to express a fructose dehydrogenase as well as to microorganisms which can be used in said method.

Abstract: A method for generating a structured surface on a substrate includes analyzing a substrate surface of the substrate and selecting, as a function of a condition of the substrate surface, method parameters including focus diameter, pulse peak power, pulse energy, point spacing, pulse length, pulse spacing and/or pulse sequence. The method further includes generating, by partial ablation and partial deposition via treatment with an intensive pulsed laser beam, surface structures having dimensions in the sub-micrometer range such that a multi-scale surface structure in the sub-micrometer and micrometer range adapted to intrinsically inhomogeneous properties of the substrate surface in the sub-micrometer range is generated. The substrate is an inhomogeneous substrate.

Abstract: The problem addressed by the invention is that of providing a coil having advantageous properties for an oscillating circuit, in particular for a measuring device for electromagnetic signals. This problem is solved in that the coil comprises an electric conductor, the ends of which form the two terminals of the coil. Wound sections of the electric conductor are twisted together, that is to say wound helically around one another. The electric conductor is in principle surrounded by insulation, for example made of plastic or varnish. As a result of the twisting, increases in spacing between adjacent conductor sections within the windings are achieved. This results in an improved quality of the coil.

Abstract: The present disclosure concerns a magnetic tunnel diode and a magnetic tunnel transistor. The magnetic tunnel diode may include two terminals for connecting to an electrical circuit as well as a tunnel junction. The magnetic tunnel transistor may include three terminals for connecting to an electrical circuit as well as a layer arrangement.

Abstract: The present invention refers to a device for generating charged particle beams with tunable orbital angular momentum. The device firstly includes one or more components for providing a charged particle beam. It is further characterized by an electrical arrangement for imparting a tunable orbital angular momentum to the charged particle beam during operation. The orbital angular momentum of the produced charged particle vortex beam is tunable by adjusting the amount of electrical current. The chirality of the produced charged particle vortex beam is switchable by reversing the direction of the electrical current. The generation of the charged particle vortex beam from the present invention does not depend on the energy of the charged particle beams. The generation of the charged particle vortex beams from the present invention is predictable and reproducible.

Abstract: The invention relates to a measuring apparatus for detecting weak electromagnetic signals from a sample at low frequencies, specifically in the frequency range of 1 kHz-10 MHz, in particular, and to a measuring method. The problem addressed by the invention is that of providing an apparatus which can be used to detect weak electromagnetic signals from a sample, in particular in the frequency range of 1 kHz-40 MHz, with a good signal-to-noise ratio. For the solution, the measuring apparatus comprises an electromagnetic resonant circuit having a pick-up coil of low quality, a preferably tunable capacitance and a filter coil; the filter coil and the capacitance have a high quality of at least 100, advantageously at least 200, particularly preferably at least 500. Alternatively or additionally, the quality of the resonant circuit is at least 100, advantageously at least 200, particularly preferably at least 500.

Abstract: The invention relates to a filter circuit which, on the hardware level, prevents charge transfers caused by one or more currents in a frequency divider (200) from generating an interference signal that can cause a signal distortion at the output of a current-to-voltage converter (300) belonging to a filter circuit. This signal distortion would otherwise have to be removed by means of laborious post-processing of the signal. In this process, the voltage curve at the input of the frequency divider (200) or the current at the second output of the frequency divider (200) are employed so that, by means of a compensation circuit arrangement, it is possible to model a compensation signal that essentially compensates for an interference signal caused by the charge transfers. The invention also relates to an associated method.

Abstract: The invention concerns a scintillation detector with which high count rates and/or high resolutions are possible. The scintillator of the claimed scintillation detector is formed from pixels (2), which are separated from each other by interstices (4). Alternatively or additionally, the surface of the scintillator is divided by grooves into pixels (2). Such a structure enables not only a particularly high resolution. When multiple detector modules are used, it also allows high count rates in the range of roughly 20 MHz.

Abstract: The present invention relates to an NADP(H) nanosensor comprising i) a nucleic acid sequence to which a regulator is capable of binding, wherein the oxidation state of the regulator depends on the NADP(H) availability; ii) a promoter sequence following the nucleic acid sequence i), to which an RNA polymerase is capable of binding, wherein the affinity of the RNA polymerase for the promoter sequence is influenced by the oxidation state of the regulator; iii) a nucleic acid sequence which is under the control of the promoter sequence ii) and which codes for an autofluorescent protein. The present invention also relates to a cell, a method for isolating genes which code for NADP(H)-dependent enzymes, and the use of an NADP(H) nanosensor.

Abstract: A device for stimulation of a patient with acoustic stimulation signals includes a stimulation unit for generating acoustic stimulation signals and a control unit for controlling the stimulation unit. The control unit is configured so that it determines a bandwidth of an auditory filter with a frequency of a predetermined tone as a center frequency, wherein this bandwidth is a reference bandwidth. The control unit determines a frequency of a first acoustic therapy signal such that a measure of coverage between the reference bandwidth around the frequency of the predetermined tone and a first bandwidth of an auditory filter with the frequency of the first acoustic therapy signal as a center frequency assumes a predetermined first value, and controls the stimulation unit such that the stimulation unit generates the first acoustic therapy signal.

Abstract: The invention relates to a voltage amplifier (100, 300) that places defined ranges (12, 14) of an input voltage signal (10) in different relations in terms of the input voltage signal (10) at one or more operating points of an amplifier circuit (130). An appropriate division of the ranges (12, 14) of the input voltage signal (10) makes it possible to linearly amplify the appertaining ranges (12, 14). Such linearly amplified output signals (191, 192, 193, 194) can then be converted into digital signals (531), for example, by means of several analog-to-digital converters (510).

Abstract: The invention relates to a filter circuit (200) comprising at least a first filter line (210). The first filter line (210) has a first input circuit (10), a first integration circuit (20) and a first output circuit (30). The first input circuit (10) is configured in such a way that, as a function of the value of the input signal, it converts an input signal into at least two distinguishable, first first-stage output signals and relays the first-stage output signals to the first integration circuit (20, 240) during a prescribed period of time. The first integration circuit (20) is configured to integrate the first first-stage output signals of the first input circuit (10) over the prescribed period of time and to generate a first integration signal (25). The first output circuit (25) is configured to compare the first integration signal (25) to a first output reference value and to generate a first second-stage output signal (35). The invention also relates to an appertaining filtering method.

Abstract: The invention concerns a maser having an electromagnetic resonant circuit comprising a pick-up coil, a capacitance and a filter coil, an active medium of organic or maser-capable molecules in the pick-up coil as well as a population inversion device for generating a population inversion in the active medium.

Abstract: A device for examining a pathological interaction between different brain areas, including a stimulation unit, which administers identical stimuli to a patient in a sequential manner, wherein the stimuli stimulate neurons of the patient in the brain areas to be examined, a measuring unit for recording measurement signals that represent a neural activity of the stimulated neurons, and a control and analysis unit for controlling the stimulation unit and for analyzing the measurement signals. The control and analysis unit transforms the measurement signals into the complex plane, examines the distribution of the phases of stimuli of the measurement signals absorbed by the measuring unit in response to the stimuli delivered to the patient, and determines the probability, with which the phase distribution differs from a uniform distribution, in order to ascertain whether a pathological interaction between the brain areas exists.

Abstract: A method is disclosed for desynchronizing neuronal brain activity of a patient in which the brain activity involves a neuron population firing in a synchronized manner. The method includes measuring a pathological frequency g of the neuronal brain activity of the patient, where the pathological frequency g relates to a pathological disorder of the patient. The method further includes calculating a stimuli frequency f based on the measured pathological frequency g, where the stimuli frequency f is calculated as being equal to the measured pathological frequency g×n/m, where n is 1, 2 or 3 and m is 1, 2 or 3, and controlling an electrode to generate stimuli in sequence with the stimuli succeeding each other at the stimuli frequency f, where the stimuli stimulate the neuron population of the patient.

Abstract: A data communication system having a plurality of input/output ports, a first group and a second group of switching units. Each switching unit has a plurality of input/output interfaces, whereby at least one of the plurality of input/output interfaces of each switching unit of the first group forms an input/output port of the communications system, and at least one other input/output interface of each of the switching units of the first group is connected via a communication link with an input/output interface of one of the switching units of the second group, so that a network is formed having at least one loop. The network is logically divided in at least two virtual subnetworks, each forming a spanning tree. Each switching unit of the first group is configured to assign an incoming data packet arriving at a particular input/output port to a predetermined one of the at least two virtual sub-networks.

Abstract: To apply a thermal barrier coating (10), a plasma jet (5) is generated by a plasma torch in a work chamber (2) and is directed to the surface of a substrate (3) introduced into the work chamber, and a ceramic coating material is applied to the substrate surface by means of PS-PVD, wherein the coating material is injected into the plasma jet as a powder and is partly or completely vaporized there. On applying the thermal barrier coating, in a first workstep the feed rate of the injected powder is set so that a large part of the injected powder vaporizes, wherein the coating material condenses from the vapor phase on the substrate surface and forms mixed phases with the material of the substrate surface.

Abstract: The invention relates to a magnetic resonance method involving the generation of high-frequency pulses and magnetic gradients (gx, gy, gz) for the selective excitation of an object to be examined. According to the invention, the magnetic resonance method is characterized in that a magnetic resonance signal s(t) according to the following signal equation is generated: s ? ( t ) = ? V ? m ( r r , T ) ? exp ? [ t ? / ? T 2 ] ? exp ? [ ? ? ? t ? ? ? s ] ? exp ? [ - ? ? ? k r ? ( T - t ) · r r ] ? ? ? 3 ? r wherein m(lr,t) stands for a desired transversal magnetization after the selective excitation, t stands for a time, {right arrow over (r)} stands for a position vector and T stands for a duration of a pulse, and whereby s(t) stands for a magnetic resonance signal, V stands for a volume that is to be examined, T2 stands for a transversal relaxation time, and ?s stands for a shift of the resonance frequency.

Abstract: A molecule mixture comprising an amphipathic molecule of type A, which has an overall positive charge in the hydrophilic region, an amphipathic molecule of type B and a polyphenol C, the method for producing the molecule mixture, and the use thereof. The molecules of types A and B are present at a molecular ratio of A:B of 1(±0.2):1(±0.2) mol/mol. A method for producing the mixture and the use is also disclosed.

Abstract: The present invention relates to a method and a device for determining attenuation areas in a body. The invention particularly relates to a method and a device for performing magnetic resonance/positron emission tomography measurements utilizing the attenuation areas determined.