Patents Assigned to Forsyth Dental
  • Glycoconjugate inhibition of Streptococcus pyrogenes adhesion
    Patent number: 5401723
    Abstract: Enhancement of the method and oral compositions for inhibiting adherence of Streptococcus pyogenes to pharyngeal and oral mucosa cells by treating these areas with a glycoconjugate comprising an oligosaccharide linked to a carrier. The oligosaccharide should have at least one fucose moiety or a galatose moiety which is free of digalactose and N-acetylneuraminyl lactose. The carrier may include albumins, starch or synthetic polymers.
    Type: Grant
    Filed: December 2, 1992
    Date of Patent: March 28, 1995
    Assignees: Colgate-Palmolive Company, Forsyth Dental
    Inventors: Abdul Gaffar, Ronald Gibbons, Stanislawa Tylewska