Abstract: Purified compounds of formula I are described. Compounds include all stereoisomeric forms and all tautomeric forms of the compounds of formula I and pharmaceutically acceptable salts and derivatives. Processes for the production of the antibacterial compounds by fermentation of the microorganism belonging to Streptomyces species (PM0626271/MTCC 5447) and to pharmaceutical compositions containing one or more of the novel compounds as active ingredient and their use in medicines for treatment and prevention of diseases caused by bacterial infections are described.
Type:
Grant
Filed:
August 31, 2010
Date of Patent:
December 10, 2019
Assignees:
National Centre for Polar and Ocean Research (NCPOR), Foundation for Neglected Disease Research (FNDR)
Abstract: The invention provides compounds of formula (I) and methods of treating a Mycobacterium infection or tuberculosis, or inhibiting DprE1 with the same.
Type:
Grant
Filed:
July 10, 2014
Date of Patent:
October 20, 2015
Assignees:
Global Alliance for TB Drug Development, Foundation for Neglected Disease Research
Inventors:
Pravin S. Shirude, Maruti N. Naik, Vikas Narayan Shinde, Shahul Hameed Peer Mohamed, Monalisa Chatterji, Radha K. Shindil