Patents Assigned to Foundation
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Patent number: 10816630Abstract: A method of obtaining analytical expressions for an optimized diffusion encoding gradient (DEG) waveform is disclosed. The method uses a constrained numerical optimization to obtain an optimal configuration of a DEG waveform. The optimization adjusts parameters for a waveform modeled as a finite set of square pulses to maximize an exact b-value equation, while maintaining a waveform shape that also compensates for motion. The optimal configuration is then verified using a waveform model of a set of trapezoidal pulses to obtain an optimal DEG waveform. Generally, the parameters describing the reduced set of trapezoidal pulses are reduced, thereby allowing the optimal DEG waveform to be expressed as closed-form analytical expressions. The analytical expressions simplify the derivation of optimal DEG waveforms for a range of diffusion imaging scanning parameters, thereby improving the quality and versatility of diffusion weighted MRI.Type: GrantFiled: June 22, 2018Date of Patent: October 27, 2020Assignee: Ohio State Innovation FoundationInventors: Waqas Majeed, Arunark Kolipaka
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Patent number: 10819152Abstract: The present application provides a wireless power transfer system including a transmitter and at least one receiver, and also provides transmitters and receivers for such systems. The transmitter includes a driver coil and a transmitter coil magnetically coupled to each other and arranged along a plane, the driver coil and the transmitter coil being tuned to resonate at differing frequencies. The receiver includes a load coil and a receiver coil magnetically coupled to each other and arranged along a plane, the load coil and the receiver coil being tuned to resonate at differing frequencies. The driver coil and the transmitter coil of the transmitter, and the load and the transmitter coil of the receiver are strongly magnetically coupled to each other. The transmitter and the receiver are magnetically coupled to each to effectuate wireless power transfer from the transmitter to the receiver.Type: GrantFiled: September 11, 2017Date of Patent: October 27, 2020Assignee: The Research Foundation for the State University of New YorkInventors: Patanjali V. Parimi, David E. Senior
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Patent number: 10814557Abstract: The present disclosure provides systems and methods for performing quality control assessments of a three dimensional (3D) printing system. In particular, the present disclosure provides a phantom designs for use in 3D printing systems, as well as methods of quality control for a 3D printing system performed using a 3D printed phantom.Type: GrantFiled: November 29, 2016Date of Patent: October 27, 2020Assignee: Mayo Foundation for Medical Education and ResearchInventors: Shuai Leng, Jane M. Matsumoto, Joel L. Kuhlmann, Kiaran P. McGee, Jonathan M. Morris
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Patent number: 10813606Abstract: Disclosed is a multi-axially variable detection module of a PET apparatus, the detection module including: a gantry having a through-hole extending from a side to an opposite side of the gantry; a detection module in which a plurality of detectors for detecting gamma rays emitted from a subject are arranged annularly along an inner circumference of the gantry; and a driving means for moving the plurality of detectors constituting the detection module in a radial direction of the detection module, wherein each of the plurality of detectors is rotatable in a longitudinal direction of the detection module to vary a length thereof in the longitudinal direction, and each of the plurality of detectors include multiple detector elements which are engaged with each other in a hinged manner in a transverse direction (circumferential direction) of the detection module to form a flat or an arc shape.Type: GrantFiled: October 31, 2017Date of Patent: October 27, 2020Assignees: Gachon University of Industry-Academic Cooperation Foundation, GIL Medical CenterInventors: Seong-Ho Seo, Sang-Yoon Lee, Jun-Young Chung, Ji-Hye Lee
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Patent number: 10817943Abstract: Systems and methods are described for aggregating and filling Volume Attentive Trade (VAT) orders using a VAT Liquidity Builder. As described, in various aspects a first grouping of VAT orders may be aggregated by the VAT Liquidity Builder. A second grouping of VAT orders may also be aggregated by the VAT Liquidity Builder. Each of the VAT orders for the first and second groups may each include a set of VAT rules that define a limit price, a share quantity and a VAT delta. The VAT Liquidity Builder may then generate an effective limit price for each of the first group of VAT orders using the corresponding limit prices and VAT deltas, and generate an execution command to fill a particular VAT order having the largest share quantity from the second group of VAT orders with one or more qualifying VAT orders from the first group.Type: GrantFiled: April 4, 2019Date of Patent: October 27, 2020Assignee: The Bartley J. Madden FoundationInventor: Bartley J. Madden
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Patent number: 10813998Abstract: Alkylphosphocholine analogs incorporating a chelating moiety that is chelated to gadolinium are disclosed herein. The alkylphophocholine analogs are compounds having the formula: or a salt thereof. R1 includes a chelating agent that is chelated to a gadolinium atom; a is 0 or 1; n is an integer from 12 to 30; m is 0 or 1; Y is —H, —OH, —COOH, —COOX, —OCOX, or —OX, wherein X is an alkyl or an arylalkyl; R2 is —N+H3, —N+H2Z, —N+HZ2, or —N+Z3, wherein each Z is independently an alkyl or an aroalkyl; and b is 1 or 2. The compounds can be used to detect solid tumors or to treat solid tumors. In detection/imaging applications, the gadolinium emits signals that are detectable using magnetic resonance imaging. In therapeutic treatment, the gadolinium emits tumor-targeting charged particles when exposed to epithermal neutrons.Type: GrantFiled: February 26, 2019Date of Patent: October 27, 2020Assignee: Wisconsin Alumni Research FoundationInventors: Jamey Weichert, Anatoly Pinchuk, Wolfgang Axel Tome
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Patent number: 10813743Abstract: Soft tissue repair grafts are provided for supporting, covering, and/or retaining an implant positioned in the body of a subject. The grafts are particularly suitable for use for pre-pectoral breast reconstruction with a breast implant or tissue expander. The grafts include positional notches for more accurate positioning in a subject. The grafts also include at least one cuff element which is folded to form a reinforced folded edge for suturing the graft more securely to adjacent tissues than previously known grafts. The grafts also include a plurality of arcuate slots which form a plurality of circular patterns arranged concentrically about a focal point, thereby enabling the grafts to expand without tearing and to conform more closely to the implant and/or adjacent body tissues such as the breast pocket, than previously known grafts. Acellular dermal matrices are particularly suitable for making the soft tissue repair grafts.Type: GrantFiled: September 7, 2018Date of Patent: October 27, 2020Assignee: Musculoskeletal Transplant FoundationInventors: Aldona Jedrysiak Spiegel, Kai-Roy Wang
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Patent number: 10818073Abstract: A system and method are provided for generating time resolved series of angiographic volume data having flow information integrated therewith. The method includes generating a series of 3D time-resolved vascular volumes from time resolved x-ray projection data and calculating blood velocity in the vascular volumes x-ray projection data to determine a rate of change of calculated contrast material arrival time at positions along the vascular volumes. The method also includes displaying the 3D time-resolved vascular volumes with a graphical indication of blood velocity in the vascular volumes.Type: GrantFiled: March 10, 2015Date of Patent: October 27, 2020Assignee: Wisconsin Alumni Research FoundationInventors: Charles A. Mistretta, Charles M. Strother
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Patent number: 10814006Abstract: The invention provides a drug conjugate comprising: 1) a therapeutic agent that comprises a phosphate, phosphonate, carboxy, or phosphoramidate group, and 2) a fluorescent group linked to the phosphate, phosphonate, carboxy, or phosphoramidate group to form the corresponding ester and salts thereof. The conjugates are useful for therapy and as probes. The invention also provides therapeutic methods for treating diseases with conjugates of the invention as well as methods for determining optimal dosages of a conjugate or a therapeutic agent for a given patient using a conjugate of the invention.Type: GrantFiled: July 14, 2016Date of Patent: October 27, 2020Assignees: University of Iowa Research Foundation, University of ConnecticutInventors: David F. Wiemer, Rocky J. Barney, Andrew Wiemer
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Patent number: 10813847Abstract: Dental prosthetic restoration coatings made of dielectric materials, methods of fabricating the same, as well as methods of testing dental prosthetic restorations are provided. A prosthetic restoration coating can include dielectric materials such as Al2O3, ZrO2, SiNx, SiC, and SiO2. Application can take place using plasma enhanced chemical vapor deposition (PECVD) methods, and alternating materials can be used to achieve desired anticorrosive, structural integrity, hardness, adhesion, and color characteristics. A testing method can include immersing a test device in solutions of differing pH, with or without abrasive steps. The cycling can include an acidic solution and a basic solution, with an optional neutral solution. As the abrasive step, a chewing simulator can be utilized.Type: GrantFiled: October 28, 2016Date of Patent: October 27, 2020Assignee: University of Florida Research Foundation, Inc.Inventors: Josephine F. Esquivel-Upshaw, Fan Ren, Arthur E. Clark
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Patent number: 10815520Abstract: Methods for diagnosis or prognosis of a cancer in a subject include isolating one or more nanovesicles from a biological sample obtained from the subject, determining the amount in the biological sample of the one or more nanovesicles, and comparing the amount of the one or more nanovesicles to a control level to thereby diagnose the cancer. The one or more nanovesicles are obtained by depleting the biological sample of exosomes prior to the isolation of the nanovesicles. Methods for identifying a tumor metastasis in a subject are also provided and include fractionating a biological sample from a subject to obtain a fraction including one or more exosomes and one or more nanovesicles having a diameter of about 8-12 nm, and then isolating the one or more nanovesicles to diagnose the tumor metastasis.Type: GrantFiled: April 9, 2018Date of Patent: October 27, 2020Assignee: University of Louisville Research Foundation, Inc.Inventor: Huang-Ge Zhang
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Patent number: 10820325Abstract: The present disclosure relates to a pre-5th-Generation (5G) or 5G communication system to be provided for supporting higher data rates Beyond 4th-Generation (4G) communication system such as Long Term Evolution (LTE). A base station apparatus according to various embodiments may comprise: a communication unit configured to transmit or receive information; and a control unit coupled to the communication unit, wherein the control unit may be configured to receive, from at least one other base station that shares a frequency band, first information associated with one or more of a second base station and a second terminal included in a second system that shares the frequency band, determine a transmission start alignment interval on the basis of the received first information, and transmit information on the transmission start alignment interval to the at least one other base station.Type: GrantFiled: August 16, 2016Date of Patent: October 27, 2020Assignees: Samsung Electronics Co., Ltd., Korea University Research and Business FoundationInventors: Seung-Hoon Park, Chung-Gu Kang, Chung-Kee Kim, Chan-Seok Yang, Jung-Min Moon
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Patent number: 10814147Abstract: A therapeutic ultrasound breast treatment device (101) is disclosed. The device (101) can include a receptacle (130) to receive a breast of a patient therein. The device (101) can also include an ultrasound transducer assembly disposed proximate the receptacle and oriented to direct a high intensity ultrasound transmission through an opening (168) of the receptacle (130) toward the breast. The device (101) can include a liner (1 60) disposed in the receptacle (130) to contain an ultrasound coupling fluid about the breast. The liner (160) can have an extension portion that extends through the opening (168) to form a seal with the ultrasound transducer assembly to prevent leakage of the ultrasound coupling fluid. A focus location of the ultrasound transmission can be adjustable and the device (101) can include a plurality of RF tracking coils to determine the focus location of the ultrasound transmission to facilitate adjustment of the focus location in an MRI environment.Type: GrantFiled: June 15, 2015Date of Patent: October 27, 2020Assignee: University of Utah Research FoundationInventors: Allison Payne, Rock J. Hadley, Robb P. Merrill, Emilee Minalga, Dennis L. Parker, Laura Lighty
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Patent number: 10813922Abstract: This document relates to methods and materials for reducing memory loss. For example, methods and materials for using inhibitors of GAT-3 polypeptide activity to reduce memory loss in mammals suffering from Alzheimer's disease are provided.Type: GrantFiled: July 3, 2018Date of Patent: October 27, 2020Assignee: The Penn State Research FoundationInventors: Gong Chen, Zheng Wu, Ziyuan Guo
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Patent number: 10815576Abstract: Disclosed herein are various layered, carbon-containing materials for use in reducing carbon dioxide. In certain embodiments, the materials comprise single wall carbon nanotubes (SWNTs).Type: GrantFiled: November 20, 2014Date of Patent: October 27, 2020Assignee: University of Florida Research Foundation, IncorporatedInventors: Andrew Gabriel Rinzler, Rajib Kumar Das, Svetlana V. Vasilyeva
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Patent number: 10819164Abstract: The present disclosure relates to an adaptive mode switching method for simultaneous wireless power/information transmission operating in a dual mode and an apparatus for performing the same. The adaptive mode switching apparatus for simultaneous wireless power/information transmission operating in a dual mode includes: an energy harvesting unit; a single tone information receiving unit; a multi-tone information receiving unit; a time-division switch; and an adaptive mode switching control unit which determines a communication mode and a modulation index based on a battery status, the magnitude of the received signal, and a data transmission rate and controls the time-division switch in accordance with the selected communication mode and modulation index.Type: GrantFiled: December 26, 2018Date of Patent: October 27, 2020Assignee: Research & Business Foundation Sungkyunkwan UniversityInventors: Dong In Kim, Jong Jin Park, Jong Ho Moon, Kang Yoon Lee
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Patent number: 10815534Abstract: This document provides methods and materials for treating cancer (e.g., estrogen receptor positive breast cancer). For example, methods and materials for identifying a mammal (e.g., a human) with cancer (e.g., estrogen receptor positive breast cancer) as having A?G variant genotype of rs6990851 and/or as having an elevated level of CSMD1 nucleic acid expression and administering one or more aromatase inhibitors (e.g., anastrozole) to treat the mammal identified as having such genotype and/or elevated level are provided.Type: GrantFiled: August 22, 2017Date of Patent: October 27, 2020Assignee: Mayo Foundation for Medical Education and ResearchInventors: Tanda T. Dudenkov, Liewei Wang, James N. Ingle, Richard M. Weinshilboum, Junmei Cairns
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Patent number: 10815442Abstract: An apparatus for producing a natural gas using carbon dioxide and water in air that includes an air-compressing member, a water collecting member, a water storing member, a carbon dioxide collecting member, a water electrolysis member, and a methanation reaction member. The water electrolysis member electrolyzes water separated from compressed air. The methanation reaction member generates a natural gas by reacting hydrogen from the electrolysis and carbon dioxide from the carbon dioxide collecting member. A method of producing a natural gas using carbon dioxide and water in air includes supplying hydrogen electrolyzed from water separated from air and carbon dioxide collected from the dry air to a methanation reaction member to generate a natural gas. A natural gas-synthesizing equipment system includes an apparatus for producing a natural gas using carbon dioxide and water in air.Type: GrantFiled: July 2, 2019Date of Patent: October 27, 2020Assignee: Sogang University Research & Business Development FoundationInventor: Kyung Byung Yoon
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Patent number: 10815125Abstract: Polymers having pendant polycyclic aromatic hydrocarbon (PAH) groups covalently bound to the polymer backbone via thioester bonds are provided. The PAH groups are covalently bound to the backbone of the polymer by a molecular linker that includes a thioester bond. Also provided are dispersions of polymer-coated carbon nanotubes and carbon nanotube films formed from the dispersions.Type: GrantFiled: January 5, 2018Date of Patent: October 27, 2020Assignee: Wisconsin Alumni Research FoundationInventors: Padma Gopalan, Michael Scott Arnold, Catherine Kanimozhi Kansiusarulsamy, Matthew John Shea
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Patent number: PP32397Abstract: A new and distinct cultivar of Nandina plant named ‘ZhNan28’, characterized by a combination of compact growing form, dense foliage, orange red (apricot) fall foliage persistent to 6 months, no seed, and no notable disease and pest.Type: GrantFiled: December 18, 2019Date of Patent: October 27, 2020Assignee: University of Georgia Research Foundation, Inc.Inventors: Donglin Zhang, Matthew Dirr, Jinying Dong