Patents Assigned to Foundation
  • METHODS OF DETECTING AND MAPPING SPINAL CORD EPIDURALLY-EVOKED POTENTIALS
    Publication number: 20200060572
    Abstract: Embodiments of the present invention relate to a novel approach to automatically detect the occurrence of evoked potentials, quantify the attributes of the signal and visualize the effect across a high number of spinal cord epidural stimulation parameters. This new method is designed to automate the current process for performing this task that has been accomplished manually by data analysts through observation of the raw EMG signals, which is laborious and time-consuming as well as being prone to human errors. The proposed method provides fast and accurate framework for activation detection and visualization of the results within five main algorithms.
    Type: Application
    Filed: December 12, 2017
    Publication date: February 27, 2020
    Applicant: University of Louisville Research Foundation, Inc.
    Inventors: Susan J. Harkema, Ayman El-Baz, Claudia Angeli, Samineh Mesbah
  • METHOD OF ACCELERATING TRAINING PROCESS OF NEURAL NETWORK AND NEURAL NETWORK DEVICE THEREOF
    Publication number: 20200065659
    Abstract: A method of accelerating a training process of a neural network includes acquiring activations used in the training process and a bit-vector corresponding to the activations, selecting activations requiring an operation from among the acquired activations by using the bit-vector, and performing backward propagation using the selected activations and filters corresponding to the selected activations.
    Type: Application
    Filed: August 26, 2019
    Publication date: February 27, 2020
    Applicants: Samsung Electronics Co., Ltd., Seoul National University R&DB Foundation
    Inventors: Seungwon LEE, Hanmin PARK, Gunhee LEE, Namhyung KIM, Joonsang YU, Kiyoung CHOI
  • MEMORY DEVICE
    Publication number: 20200066319
    Abstract: The present invention provides a memory device in which a lower electrode, a seed layer, synthetic antiferromagnetic layers, a separation layer, a magnetic tunnel junction, a capping layer, and an upper electrode are formed on a substrate in a laminated manner, wherein a diffusion barrier is formed between the magnetic tunnel junction and the capping layer. In addition, the present invention provides a memory device in which a lower electrode, a seed layer, synthetic antiferromagnetic layers, a separation layer, a magnetic tunnel junction, a capping layer, and an upper electrode are formed on a substrate in a laminated manner, wherein the seed layer is formed of a material that allows the synthetic antiferromagnetic layers to grow in the FCC (111) direction.
    Type: Application
    Filed: November 1, 2019
    Publication date: February 27, 2020
    Applicant: Industry-University Cooperation Foundation Hanyang University
    Inventors: Jea Gun PARK, Du Yeong Lee, Seung Eun Lee
  • SATIATION PEPTIDE ADMINISTRATION
    Publication number: 20200061158
    Abstract: Disclosed herein are compositions and methods for treating obesity involving satiation gut peptide administration to the mouth of a subject for a predetermined dose and frequency. In other embodiments, materials and methods of treating certain psychological disorders are disclosed involving satiation gut peptides. In exemplary embodiments, the satiation gut peptide pertains to PYY.
    Type: Application
    Filed: September 5, 2019
    Publication date: February 27, 2020
    Applicant: University of Florida Research Foundation, Inc.
    Inventors: Sergei Zolotukhin, Andres Acosta
  • COMPOUNDS AND METHODS FOR TREATING CANCER
    Publication number: 20200061055
    Abstract: The present application provides methods and compositions for treating cancer, for example, renal cell carcinoma, melanoma, ovarian, breast, prostate, colon, pancreatic, bladder, liver, lung, and thyroid cancer, and more particularly to using an inhibitor of a stearoyl-Coenzyme A desaturase 1 (SCD1) enzyme in combination with a checkpoint inhibitor to treat these disorders.
    Type: Application
    Filed: February 28, 2018
    Publication date: February 27, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Christina Von Roemeling, Han W. Tun, John A. Copland, III, Thomas R. Caulfield, Yon Son Betty Kim
  • MICRONEEDLE WITH POROUS COATING LAYER, MANUFACTURING METHOD THEREOF AND MICRONEEDLE PATCH WITH THE SAME
    Publication number: 20200061358
    Abstract: A method of manufacturing a microneedle includes: an emulsion producing operation of dissolving a soft material as a raw material of the coating layer in a solvent and mixing porogen with the dissolved soft material to produce emulsion; an emulsion coating operation of coating the emulsion on a surface of the needle body; an emulsion drying operation of drying the emulsion in the needle body after the emulsion coating operation; and a porogen removing operation of removing the porogen from the emulsion dried in the needle body, and the method further comprising a body manufacturing operation of using metal to manufacture the needle body, wherein the porogen comprises at least one of phosphate buffer saline (PBS), water-soluble hydrogel, and salt.
    Type: Application
    Filed: October 30, 2019
    Publication date: February 27, 2020
    Applicant: Kyungpook National University Industry-Academic Cooperation Foundation
    Inventor: Gyu Man KIM
  • METHODS OF NANOSCALE DIRECTIONAL WETTING AND USES THEREOF
    Publication number: 20200061667
    Abstract: This invention discloses a method for controlling nanoscopic wetting near or at a molecular scale for synthetic material applications. In particular this invention relates to a method for preparing a monolayer or thin film with a patterned nanoscopic wetting surface using a ‘sitting’ phase of polymerizable amphiphile, wherein hydrophobic alkyl chains of the amphiphile extend along the supporting surface and the amphiphile molecules align side-to-side, effectively forming a repeating cross-section of bilayer with alternating hydrophilic and hydrophobic stripes of a ˜6 nm pitch tunable based on the chain length of the amphiphile. Products prepared according to the methods disclosed herein are within the scope of this invention. In some embodiments, monolayers or thin films so prepared are transferable.
    Type: Application
    Filed: October 28, 2019
    Publication date: February 27, 2020
    Applicant: Purdue Research Foundation
    Inventors: Shelley A Claridge, Shi Wah Choong, Jae Jin Bang, Shane Russell
  • SYSTEMS AND METHODS FOR ANIMAL PATIENT HEALTH MANAGEMENT DURING VETERINARY PROCEDURES
    Publication number: 20200060616
    Abstract: Implementations described and claimed herein provide systems and methods for managing animal patient during a veterinary procedure. In one implementation, a base has an interior surface, an exterior surface, and an opening. An electrode is disposed in the opening. The electrode is configured to communicate with medical device(s) for monitoring vital(s) of the patient during the procedure. A thermal insulator extends from the base. The thermal insulator forms a housing. An internal cavity is defined within the housing. The foot of the patient is receivable into the internal cavity. The thermal insulator regulates the body temperature of the animal patient during the veterinary procedure by retaining heat within the internal cavity.
    Type: Application
    Filed: August 21, 2019
    Publication date: February 27, 2020
    Applicant: Colorado State University Research Foundation
    Inventor: Natalie M. Malkut
  • THIOPHENE MONOAMINE BASED ORGANIC-INORGANIC HYBRID PEROVSKITES
    Publication number: 20200062740
    Abstract: The present disclosure relates to novel thiophene monoamine based organic-inorganic hybrid perovskites, and the method of making and using the novel organic-inorganic hybrid perovskites.
    Type: Application
    Filed: July 8, 2019
    Publication date: February 27, 2020
    Applicant: Purdue Research Foundation
    Inventors: Letian Dou, Yao Gao
  • ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS
    Publication number: 20200062698
    Abstract: The present invention provides a compound having the structure:
    Type: Application
    Filed: June 24, 2019
    Publication date: February 27, 2020
    Applicant: The Research Foundation for the State University of New York
    Inventors: Maurizio Del Poeta, Visesato Mor
  • TARGETING DNA-PKCS AND B7-H1 TO TREAT CANCER
    Publication number: 20200061077
    Abstract: Materials and methods for treating potentially chemoresistant tumors (e.g., using DNA-PKcs inhibitors and anti-B7-H1 antibodies) are provided herein.
    Type: Application
    Filed: November 12, 2019
    Publication date: February 27, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventor: Haidong Dong
  • METHODS AND MATERIALS FOR USING FIBRIN SUPPORTS FOR RETINAL PIGMENT EPITHELIUM TRANSPLANTATION
    Publication number: 20200061246
    Abstract: This document provides methods and materials for performing retinal pigment epithelium transplantation. For example, methods and materials for using fibrin supports for retinal pigment epithelium transplantation are provided.
    Type: Application
    Filed: November 13, 2017
    Publication date: February 27, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Alan D. Marmorstein, Raymond Iezzi, Jarel K. Gandhi, Jose S. Pulido
  • EXOSOMAL BIOMARKERS FOR DIAGNOSIS AND PROGNOSIS OF CANCER AND RELATED METHODS
    Publication number: 20200063208
    Abstract: Methods for diagnosing a cancer in a subject are provided in which a biological sample is provided from a subject including one or more exosomes. The exosomes are isolated from the biological sample and are used to identify a type and/or amount of one or more tumor suppressor miRNAs encapsulated by the exosomes. A measurable difference in the type and/or amount of the tumor suppressor miRNAs as compared to control levels allows for a diagnosis of cancer in the subject. Methods of selecting or modifying a treatment and methods for determining whether to initiate or continue prophylaxis or treatment for a cancer based on the exosomal miRNAs is further provided.
    Type: Application
    Filed: October 13, 2017
    Publication date: February 27, 2020
    Applicant: University of Louisville Research Foundation, Inc.
    Inventor: Huang-Ge Zhang
  • PROSTATE CANCER DIAGNOSTIC BIOMARKER COMPOSITION INCLUDING KYNURENINE PATHWAY'S METABOLITES
    Publication number: 20200064349
    Abstract: Disclosed is a prostate cancer diagnostic biomarker composition including, as an active ingredient, at least one kynurenine pathway metabolite selected from kynurenine and anthranilate. Also disclosed are a prostate cancer diagnostic composition including an agent capable of measuring the level of the biomarker and a prostate cancer diagnostic kit including the prostate cancer diagnostic composition. The use of the prostate cancer diagnostic biomarker composition can significantly improve the accuracy of prostate cancer diagnosis as an alternative or supplement to the use of PSA levels for prostate cancer diagnosis according to the prior art, which has difficulty in ensuring accurate diagnosis. Therefore, the biomarker composition can be widely used in a variety of industrial applications, including medical applications.
    Type: Application
    Filed: August 23, 2019
    Publication date: February 27, 2020
    Applicants: Korea University Research and Business Foundation, Sejong Campus, Industry-Academic Cooperation Foundation, Yonsei University
    Inventors: Youngja PARK HWANG, Adnan KHAN, Jinhyuk NA, Sun ha JEE
  • NONLINEAR MASS SENSORS BASED ON ELECTRONIC FEEDBACK
    Publication number: 20200064310
    Abstract: This present disclosure relates to sensors capable of sensing mass, stiffness, and chemical or biological substances. More specifically, this disclosure provides the design and implementation of a piecewise-linear resonator realized via diode- and integrated circuit-based feedback electronics and a quartz crystal resonator. The proposed system is fabricated and characterized, and the creation and selective placement of the bifurcation points of the overall electromechanical system is demonstrated by tuning the circuit gains. The demonstrated circuit operates around at least 1 MHz.
    Type: Application
    Filed: December 4, 2018
    Publication date: February 27, 2020
    Applicant: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, George Tsu-Chih Chiu, Nikhil Bajaj
  • METHOD FOR PROTECTING SKELETONIZED BLOOD VESSELS
    Publication number: 20200061244
    Abstract: Skeletonized blood vessels for use as vascular grafts are protected from biomechanical injury and/or certain cellular and extracellular changes by application of a biocompatible hydrogel to the vessel exterior. The hydrogel may be applied to the vessel graft before or after harvesting from a donor patient.
    Type: Application
    Filed: November 3, 2017
    Publication date: February 27, 2020
    Applicants: University of Delaware, The Nemours Foundation
    Inventors: Robert AKINS, Kristi L. Kiick, Karyn ROBINSON, Rebecca SCOTT
  • Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof
    Publication number: 20200064334
    Abstract: An in silico screening method generated compounds that are against laminin receptor 37LR and their anti-cancer functions in prostate cancer cell lines are disclosed herein. A group of derivatives based on the hit compound from the in silico screening are synthesized and tested with improved IC50 value that can have relevant clinical use for prostate cancer or osteoarthritis.
    Type: Application
    Filed: August 29, 2019
    Publication date: February 27, 2020
    Applicant: Purdue Research Foundation
    Inventors: Marxa L. Figueiredo, Charles Samuel Umbaugh, Herman O. Sintim, Adriana Diaz-Quinones
  • Fluoroscopy system resolving slowly evolving conditions
    Patent number: 10568598
    Abstract: A fluoroscopy machine allows programming of a frame rate in the range of multiple seconds per frame and then displays the images at a higher rate in a loop in the radiological theater so as to impart an improved sense of motion to a human observer of a slow physiological processes captured by fluoroscopic studies.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: February 25, 2020
    Assignee: Wisconsin Alumni Research Foundation
    Inventor: Myron A. Pozniak
  • Management of corn rootworm and other insect pests
    Patent number: 10570413
    Abstract: Trap and/or refuge crops and methods of use in managing corn rootworm and other insect pests of maize are provided. Some methods involve using trap crops comprising plants with enhanced susceptibility to one or more insect pests to lure and kill insect pests. Other methods involve using refuge crops comprising plants with enhanced susceptibility to one or more insect pests to monitor insect pest populations in an area or to promote mating between insecticide resistant and insecticide non-resistant insects.
    Type: Grant
    Filed: September 20, 2013
    Date of Patent: February 25, 2020
    Assignees: Purdue Research Foundation, E.I. du Pont de Nemours and Company, Pioneer Hi-Bred International, INC.
    Inventors: John Lindsey Flexner, Gurmukh S. Johal, Dilbag S. Multani, James K. Presnail, Scott V. Tingey
  • Photodegradable polycaprolactone fumarate block copolymers
    Patent number: 10568985
    Abstract: A polycaprolactone fumarate copolymer useful as a material for a biocompatible scaffold for tissue engineering applications is disclosed. The copolymer includes at least one caprolactone unit, at least one fumarate unit, and at least one third unit selected from the group consisting of acrylate units and styrenic units. A linking moiety forms a link between the third unit and at least one caprolactone unit or at least one fumarate unit. The linking moiety can be photodegradable. In one form, the third unit includes at least one methyl methacrylate unit. The copolymer can be used to form the wall of a nerve conduit.
    Type: Grant
    Filed: July 31, 2013
    Date of Patent: February 25, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Michael Brett Runge, Michael J. Yaszemski