Abstract: A viral vector delivery system for both respiratory and digestive tracts of pigs and an application thereof are provided. The viral vector delivery system includes a backbone plasmid and a helper plasmid. The backbone plasmid is produced by inserting a full-length cDNA of porcine enterovirus B (PEVB) into a pUC57 plasmid. The helper plasmid is produced by inserting a green fluorescent protein-coding gene into a plasmid pCAG-T7-polymerase. The viral vector delivery system can be constructed with high efficiency, can quickly cause a cytopathic effect (CPE) after infecting cells, has a viral titer up to 107.75 TCID50/mL, and can maintain high stability. A pathogenic epitope for the respiratory and digestive tracts of pigs is inserted into the backbone plasmid to produce a vaccine antigen, which is non-pathogenic, has high stability and a high viral titer, and allows a prominent immunization effect after being inoculated in pigs.

Abstract: A biomarker composition for predicting susceptibility to a therapeutic agent for neurofibromatosis by using Ras activity; and a pharmaceutical composition for preventing or treating neurofibromatosis, including a Ras activity inhibitor. The biomarker composition can accurately diagnose susceptibility to a therapeutic agent for neurofibromatosis by measuring the expression levels of a GTP-bound and activated Ras (Ras-GTP) protein and an activated p-ERK protein or a gene encoding the same in a biological sample of an individual. The pharmaceutical composition inhibits the activity of Ras proteins, and thus can be effectively used for the prevention or treatment of neurofibromatosis in which the activity of the Ras proteins is increased.

Abstract: There is provided an apparatus for calculations based on a systolic array, comprising: a memory in which one or more operand data chunks are stored, a conveyor queue configured to shift the one or more operand data chunks in sequence and one or more synchronous processing units (SPUs) including one or more processing elements (PEs), and configured to access the operand data chunks shifted along the conveyor queue, wherein the one or more processing elements perform calculations based on the operand data chunks that the synchronous processing unit including each processing element has accessed.

Abstract: The present invention relates to a method and apparatus for encoding and decoding a video image based on transform. The method for decoding a video includes: determining a transform mode of a current block; inverse-transforming residual data of the current block according to the transform mode of the current block; and rearranging the inverse-transformed residual data of the current block according to the transform mode of the current block, wherein the transform mode includes at least one of SDST (Shuffling Discrete Sine Transform), SDCT (Shuffling Discrete cosine Transform), DST (Discrete Sine Transform) or DCT (Discrete Cosine Transform).

Abstract: A heterostructured catalyst includes a 2-dimensional (2D) array of titanium including nanocavities that are all directly attached to a substrate. Each of the titanium including nanocavities have a pore with a nanopore size and a wall with a nanowall thickness. The titanium including nanocavities can be titania nanocavities with a metal layer or a metal compound layer on the titania nanocavities including inside the pores, or the titanium including nanocavities can include SrTiO3 or consist of SrTiO3, each with a surface layer of reduced SrTiO3.

Abstract: Radial-armed thin-film bilayers are designed and fabricated from a metal and an oxide to produce grippers that interact with the yarns or fibers of the fabric and form a mechanical tangle attachment to the fabric. MEMs devices attached to the grippers enable the MEMs devices to be adhered to a flexible and/or extensible fabric. Fabrics comprise conventional textile, smart textiles, functional fibers or other smart materials. The fabrics thus incorporate wearable sensors, medical devices, and other functional MEMs for commercial, biomedical, industrial and scientific applications.

Abstract: An insulin monitoring system includes one or more processors, one or more computer-readable storage devices, and program instructions stored on at least one of the one or more storage devices for execution by at least one of the one or more processors. The program instructions include: first program instructions to track, in real time, the amount of insulin active in a patient; second program instructions to calculate the amount of insulin need of the patient by tracking the patient's metabolic states; third program instructions to compare the insulin active in the patient with the insulin need of the patient; and fourth program instructions to determine an insulin fault level based on the comparison.

Abstract: A metamaterial electromagnetic absorber includes a substrate having a first surface on which electromagnetic waves are incident and a second surface opposite the first surface. The substrate is made of a metamaterial. The metamaterial electromagnetic absorber also includes a first inductive conduction pattern and a second inductive conduction pattern formed on the first surface and the second surface, respectively.

Abstract: An embodiment of the present invention provides a noble gas hydride having the following formula 1: NgnHm. In formula 1, Ng represents a noble gas atom, n represents an integer from 1-8, and m represents an integer from 1-46.

Abstract: Disclosed is a perovskite light-emitting device with reduced defects in a perovskite thin film. The passivation layer in the perovskite light-emitting device is formed on the upper part of the perovskite thin film to eliminate defects in the perovskite nanocrystalline particles and resolve charge imbalance in the device, thereby improving maximum efficiency and maximum luminance of the light-emitting device.

Abstract: The present invention relates to a method for manufacturing a membrane-electrode assembly and a membrane-electrode assembly manufactured thereby, and more specifically, to a method for manufacturing a membrane-electrode assembly by using a nano-dispersed ionomer binder under supercritical conditions in a mixed solvent comprising alcohol and water, and a membrane-electrode assembly manufactured thereby and a fuel cell or water electrolysis device comprising same.

Abstract: A semiconductor system including a transmitter configured to output a plurality of data as a plurality of data input/output signals through a plurality of channels based on a matrix E, and a receiver configured to generate the plurality of data by differentially amplifying the plurality of data input/output signals received through the plurality of channels based on a matrix D, in which all components of the matrix E and the matrix D are integers, a product matrix of the matrix D and the matrix E is a diagonal matrix, a sum of the components of each row of the matrix D is 0, and a sum of absolute values of the components of each column of the matrix D is less than or equal to a threshold value.

Abstract: Disclosed are titanium alloys for use in additive manufacturing that comprise a titanium material and a beta eutectoid stabilizer. The beta eutectoid stabilizer can be present in an effective amount to produce an equiaxed grain structure when the titanium alloy is melted or sintered during an additive manufacturing process. Also provided are methods of forming objects via additive manufacturing processes as well as methods of forming titanium alloys for use in additive manufacturing.

Abstract: A pre-prodrug, comprising a drug, e.g., doxorubicin, which has off-target toxicity (e.g., cardiotoxicity) with respect to its antineoplastic activity, and an amine functionality of the drug incorporated into a disubstituted maleimide (DMI). The pre-prodrug may be linked to a targeting or de-targeting agent or a polar modulator, e.g., charged ligand, amino acid, peptide, etc., to increase therapeutic index. The pre-prodrug is hydrolyzed to the prodrug, having a disubstituted maleamic acid (DMA). A polar modulator such as glutamic acid prevents cellular uptake of the prodrug, but not the doxorubicin drug released from the prodrug after dissociation. The prodrug is pH sensitive, and below pH 7.0, tends to cleave to form free drug and cyclized maleic anhydride. Tumor environments tend to be more acidic, e.g., pH 6.8, than cardiac tissue, e.g., pH 7.4, and therefore the heart is spared while the drug is selectively released within a tumor.

Abstract: An augmented reality (AR) device and a method of predicting a pose in the AR device is provided. In the augmented reality (AR) device inertial measurement unit (IMU) values corresponding to the movement of the AR device are obtained at an IMU rate, intermediate 6-degrees of freedom (6D) poses of the AR device are estimated based on the IMU values and images around the AR device via a visual-inertial simultaneous localization and mapping (VI-SLAM) module, and a pose prediction model for predicting relative 6D poses of the AR device is generated by performing learning by using a deep neural network.

Abstract: The present invention provides antibody compounds that contain a substitution of arginine for the reactive lysine residue (Lys99) in the hydrophobic cleft (38C2_Arg). The invention also provides antibody drug conjugate compounds (ADCs) that contain cargo moieties that are site-specifically conjugated to the engineered arginine residue in the 38C2_Arg variant antibody. Further provided in the invention are therapeutic applications of the compounds.

Abstract: In accordance with an embodiment, a noise reduction device includes a housing; and a slit located inside the housing and having a unit cell located therein, the unit cell comprising a sound absorbing layer configured to absorb noise generated from a sound source inside the housing, and a meta-material panel layer located on one surface of the sound absorbing layer, the meta-material panel layer comprising a sound meta-material.

Abstract: Methods, computer program products, and systems can include, for example: receiving a plurality of signal instances of a signal emitted by a transmitter, wherein respective signal instances of the plurality of signal instances are collected at different positions. There is also set forth herein receiving by a movable receiver moving within a first location a plurality of signal instances of a signal emitted by a transmitter, wherein signal instances defining the plurality of signal instances are collected by the moveable receiver at different respective receiver positions within the first location. There is also set forth herein discovering a direction of arrival parameter value that specifies a direction of arrival of the signal emitted by the transmitter, wherein the discovering includes using a set of signal instances from the plurality of signal instances.

Abstract: A code sequence based intelligent key code identification method includes extracting Smali code sequence by decompiling an application, vectorizing the extracted Smali code sequence to construct a training dataset, training a deep learning model with the vectorized Smali code sequence to generate a classifier, generating a category classification result using Smali code sequence of a target application as input of the classifier, and identifying and providing important Smali code sequence from which the classification result of the target application is derived. Accordingly, it is possible to objectively evaluate the application using Smali code sequence of the application being actually run.

Abstract: The filter for carbon dioxide adsorption according to the present invention is composed of multiple unit filters that are mutually connected and stacked, and the unit filters include a repeating three-dimensional patterned part formed using one selected from vat photopolymerization, powder bed fusion, or additive manufacturing processes; flow paths formed in the three-dimensional patterned part; a three-dimensional exposed surface that is exposed to the mixed gas flowing through the flow paths; and a carbon dioxide adsorption layer coated on the exposed surface.