Patents Assigned to Fournier Laboratories Ireland Ltd.
  • Nanoparticulate fibrate formulations
    Patent number: 7931917
    Abstract: The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Grant
    Filed: May 23, 2007
    Date of Patent: April 26, 2011
    Assignees: Elan Pharma International, Ltd., Fournier Laboratories Ireland, Ltd.
    Inventors: Tuula Ryde, Evan E. Gustow, Stephen B. Ruddy, Rajeev Jain, Rakesh Patel, Michael John Wilkins
  • Nanoparticulate fibrate formulations
    Patent number: 7927627
    Abstract: The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Grant
    Filed: May 23, 2007
    Date of Patent: April 19, 2011
    Assignees: Elan Pharma International, Ltd., Fournier Laboratories Ireland, Ltd.
    Inventors: Tuula Ryde, Evan E. Gustow, Stephen B. Ruddy, Rajeev Jain, Rakesh Patel, Michael John Wilkins
  • Process for preparing quaternary acid and ammonium salts
    Patent number: 7714163
    Abstract: A process for preparing a quaternary ammonium salt of a fibric acid, represented by the following reaction scheme: is carried out in a single operation starting from a phenol of formula (I), an ?-halogenated ester of formula (II) and a quaternary ammonium hydroxide of formula (III). This process makes it possible economically to prepare a choline salt of fenofibric acid in high purity that can be used directly as the active substance in a pharmaceutical composition intended for human consumption.
    Type: Grant
    Filed: April 28, 2008
    Date of Patent: May 11, 2010
    Assignee: Fournier Laboratories Ireland Ltd.
    Inventors: Philippe Dellis, Kamel Nasar
  • SALTS OF FENOFIBRIC ACID AND PHARMACEUTICAL FORMULATIONS THEREOF
    Publication number: 20090263477
    Abstract: In one aspect, the present invention relates to a formulation in the form of molecular dispersion comprising i) fenofibric acid, a physiologically acceptable salt or derivative thereof and optionally other active substances, ii) a binder component comprising at least one enteric binder, and optionally iii) other physiologically acceptable excipients. In a second aspect, the present invention relates to novel salts of fenofibric acid that are photostable when compared to other salts of fenofibric acid.
    Type: Application
    Filed: June 23, 2009
    Publication date: October 22, 2009
    Applicants: ABBOTT LABORATORIES, FOURNIER LABORATORIES IRELAND LTD
    Inventors: Russell D. Cink, Joseph B. Paterson, Yi Gao, Geoff G. Z. Zhang, Michelle A. Long, John B. Morris, Joerg Rosenberg
  • Process for Preparing Quaternary Acid and Ammonium Salts
    Publication number: 20080275270
    Abstract: A process for preparing a quaternary ammonium salt of a fibric acid, represented by the following reaction scheme: is carried out in a single operation starting from a phenol of formula (I), an ?-halogenated ester of formula (II) and a quaternary ammonium hydroxide of formula (III). This process makes it possible economically to prepare a choline salt of fenofibric acid in high purity that can be used directly as the active substance in a pharmaceutical composition intended for human consumption.
    Type: Application
    Filed: April 28, 2008
    Publication date: November 6, 2008
    Applicant: Fournier Laboratories Ireland Ltd
    Inventors: Philippe Dellis, Kamel Nasar
  • Methods of treatment using nanoparticulate fenofibrate compositions
    Patent number: 7320802
    Abstract: The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Grant
    Filed: October 27, 2003
    Date of Patent: January 22, 2008
    Assignees: Elan Pharma International, Ltd., Fournier Laboratories Ireland Ltd.
    Inventors: Tuula Ryde, Evan E. Gustow, Stephen B. Ruddy, Rajeev Jain, Rakesh Patel, Michael John Wilkins
  • Nanoparticulate fibrate formulations
    Patent number: 7276249
    Abstract: The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Grant
    Filed: May 23, 2003
    Date of Patent: October 2, 2007
    Assignees: Elan Pharma International, Ltd., Fournier Laboratories Ireland Ltd.
    Inventors: Tuula Ryde, Evan E. Gustow, Stephen B. Ruddy, Rajeev Jain, Rakesh Patel, Michael John Wilkins
  • Nanoparticulate fibrate formulations
    Publication number: 20030224058
    Abstract: The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.
    Type: Application
    Filed: February 21, 2003
    Publication date: December 4, 2003
    Applicants: Elan Pharma International, Ltd., Fournier Laboratories Ireland, Ltd.
    Inventors: Tuula Ryde, Evan E. Gustow, Stephen B. Ruddy, Rajeev Jain, Rakesh Patel, Michael John Wilkins