Abstract: A system and method of determining point-of-purchase placement locations for printed promotional materials on a retail structure includes loading, by a processing device from a database, data representative of a retail structure; determining a plurality of advertisement placement locations on the retail structure; determining a point-of-placement priority value for each of the plurality of advertisement placement locations; receiving an advertising campaign comprising data representing a plurality of advertising campaign items, each item including an associated item priority value; determining a location on the retail structure for each of the advertising campaign items based upon the item priority values and the point-of-placement priority values; and providing a report to an operator of the retail structure indicating where each of the advertising campaign items is to be displayed on the retail structure.