Abstract: A method of detecting ovarian cancer in a female test subject comprising determining the amount of plasmenyl-PA or a biomarker having a mass charge ratio of approximately 655.3 in a sample of a bodily fluid taken from the female test subject and comparing the amount of plasmenyl-PA (or the biomarker) in the sample of the bodily fluid taken from the female test subject to a range of amounts of plasmenyl-PA (or the biomarker) found in samples of bodily fluids taken from a group of normal female subjects of the same species as the female test subject and lacking ovarian cancer, whereby a lower amount of the plasmenyl-PA (or the biomarker) in the sample of the bodily fluid taken from the female test subject indicates the presence of ovarian cancer.
Type:
Grant
Filed:
November 10, 2006
Date of Patent:
February 17, 2009
Assignees:
Frantz Biomarkers, LLC, The Cleveland Clinic Foundation
Abstract: A method of detecting an inflammatory disease or a cancer in a test subject comprising determining the amount of plasmenyl-PE or a biomarker having a mass charge ratio of approximately 698.2, 722.2, 726.2 or 750.2 in a sample of bodily fluid taken from the test subject and comparing the amount of plasmenyl-PE (or the biomarker) in the sample of the bodily fluid from the test subject to a range of amounts of plasmenyl-PE (or the biomarker) found in samples of the bodily fluid from a group of normal subjects of the same species as the test subject and lacking the inflammatory disease or the cancer, whereby a change in the amount of the plasmenyl-PE (or the biomarker) (such as a lower amount) in the sample of the bodily fluid from the test subject indicates the presence of the inflammatory disease or the cancer.
Abstract: A method of detecting ovarian cancer in a female test subject comprising determining the amount of plasmenyl-PA or a biomarker having a mass charge ratio of approximately 655.3 in a sample of a bodily fluid taken from the female test subject and comparing the amount of plasmenyl-PA (or the biomarker) in the sample of the bodily fluid taken from the female test subject to a range of amounts of plasmenyl-PA (or the biomarker) found in samples of bodily fluids taken from a group of normal female subjects of the same species as the female test subject and lacking ovarian cancer, whereby a lower amount of the plasmenyl-PA (or the biomarker) in the sample of the bodily fluid taken from the female test subject indicates the presence of ovarian cancer.
Type:
Application
Filed:
November 10, 2006
Publication date:
August 23, 2007
Applicants:
FRANTZ BIOMARKERS, LLC, THE CLEVELAND CLINIC FOUNDATION