Abstract: Certain peptide molecules can be used as the basic structures (template molecules) for inhibiting and analysing amyloid formation and cytotoxicity in amyloid illnesses. These peptides have an effect on the molecules which are responsible for the amyloid illnesses (for their part amyloid-forming peptides and proteins). The peptides are thus either inhibitors themselves or agonists of amyloid formation and cytotoxicity or can serve as a template for identifying and producing further inhibitors and agonists and can be used as molecular tools during analysis.
Type:
Grant
Filed:
June 12, 1998
Date of Patent:
March 19, 2002
Assignee:
Fraunhofer-Gesellschaft zur Forferung der angewandten
Forschung e.V.
Inventors:
Afroditi Kapurniotu, Jürgen Bernhagen, Herwig Brunner