Patents Assigned to Fraunhofer USA, Inc.
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Publication number: 20200181203Abstract: A fusion protein comprising a first recombinant viral coat protein, a second recombinant viral coat protein and a first linkage peptide is provided. The first recombinant viral coat protein is linked to N-terminus of the first linkage peptide. The second recombinant viral coat protein is linked to C-terminus of the first linkage peptide. The first and second recombinant viral coat proteins are derived from the coat protein (CP) of alfalfa mosaic virus (AIMV). The fusion protein may form a virus like particle (VLP). Where the fusion protein further comprises a target protein, the target protein may be displayed on the surface of the VLP. Also provided are methods for producing the fusion protein and the VLP as well as the uses of the fusion protein and/or the VLP.Type: ApplicationFiled: November 10, 2017Publication date: June 11, 2020Applicant: Fraunhofer USA Inc.Inventors: Stephen Tottey, Konstantin Musiychuk
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Publication number: 20190296683Abstract: Described herein are embodiments of an approach to attaching one or more photovoltaic (PV) modules to a roof of a building. More particularly, described herein are embodiments of an approach to attaching glass-glass PV modules using an adhesive. Such an adhesive may be applied to contact points between the roof and a support frame that holds the glass-glass PV module(s) in place and that may be mechanically coupled to the glass-glass PV module(s). Use of the adhesive in this way may be particularly advantageous when the roof is sloped, including when the roof has a steep slope, which may include roofs having a rise-to-run ratio greater than 4:12, greater than 6:12, or greater than 8:12. The adhesive may, in some embodiments, aid in reducing, minimizing, or eliminating the use of mechanical anchor points that may be needed to support the glass-glass PV module(s) on the roof.Type: ApplicationFiled: March 21, 2018Publication date: September 26, 2019Applicant: Fraunhofer USA, Inc.Inventors: Christian Honeker, Christian Hoepfner, Hans C. Henning
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Patent number: 10381837Abstract: Photovoltaic systems and related techniques are provided. A method for commissioning a photovoltaic (PV) system may include obtaining data describing an arrangement of two or more components of the PV system; performing a test of the PV system, wherein performing the test includes determining whether the PV system complies with at least one PV system criterion based, at least in part, on at least a portion of the data describing the arrangement of the two or more components of the PV system; and in response to determining that the PV system complies with the at least one PV system criterion, activating the PV system and/or notifying a user of the PV system that the PV system complies with the at least one PV system criterion. The method may further include sending information associated with the PV system to a regulatory entity and/or an operator of an electrical grid.Type: GrantFiled: July 14, 2015Date of Patent: August 13, 2019Assignee: Fraunhofer USA, Inc.Inventors: Christian Hoepfner, Dirk E. Mahling, Matthew Alan Kromer, James R. Perkinson
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Publication number: 20180110404Abstract: Disclosed herein is an aspiration assembly for attaching to an endoscope. The aspiration assembly comprises an extendable suction tube for aspirating an object (e.g., smoke, blood, blood clot, bone debris, or tissue debris) at or near a surgical site during an endoscopic surgery. The aspiration assembly can further comprise an irrigation tube for directing a fluid to the surgical site for cleaning the endoscope lens. By integrating an extendable suction tube with the endoscope, the technology described herein obviate the need for instrument switching and/or multiple surgeons during the surgery.Type: ApplicationFiled: April 15, 2016Publication date: April 26, 2018Applicants: TRUSTEES OF BOSTON UNIVERSITY, BOSTON MEDICAL CENTER CORPORATION, FRAUNHOFER USA, INC.Inventors: Anand DEVAIAH, Andre SHARON, Alexis SAUER-BUDGE, Holger WIRZ, Yuzhang YANG, Stephanus Johannes Marcellis VAN DER KEMP, Daniel ECHEVERRIA
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Publication number: 20180087798Abstract: Systems and methods for characterization of retrofit opportunities are described. The methods may comprise computing, using at least one computing device disposed remote from a building and based at least in part on heating, ventilation and air conditioning (HVAC) runtime data associated with the building, one or more thermal characteristics of the building. In some embodiments, a model-predicted indoor temperature may be fitted against thermal data measured by a thermostat at the building. The thermal characteristic of the building may comprise a thermal insulation, an air leakage rate and/or an HVAC efficiency. The method may be used to determine, using the at least one computing device, suitability of the building for a retrofit opportunity to improve energy efficiency of the building. Determining the suitability may comprise evaluating the one or more thermal characteristics. The HVAC runtime data may be computed based on data received from a thermostat or a meter, such as an electric or a gas meter.Type: ApplicationFiled: August 18, 2017Publication date: March 29, 2018Applicant: Fraunhofer USA, Inc.Inventors: Michael Zeifman, Amine Lazrak
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Publication number: 20180068034Abstract: Systems and methods for characterization of retrofit opportunities are described. The methods may comprise computing, using at least one computing device disposed remote from a building and based at least in part on heating, ventilation and air conditioning (HVAC) runtime data associated with the building, one or more thermal characteristics of the building. In some embodiments, a model-predicted indoor temperature may be fitted against thermal data measured by a thermostat at the building. The thermal characteristic of the building may comprise a thermal insulation, an air leakage rate and/or an HVAC efficiency. The method may be used to determine, using the at least one computing device, suitability of the building for a retrofit opportunity to improve energy efficiency of the building. Determining the suitability may comprise evaluating the one or more thermal characteristics. The HVAC runtime data may be computed based on data received from a thermostat or a meter, such as an electric or a gas meter.Type: ApplicationFiled: August 18, 2017Publication date: March 8, 2018Applicant: Fraunhofer USA, Inc.Inventors: Michael Zeifman, Amine Lazrak
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Patent number: 9817045Abstract: Identification and tracking of major electric appliances by using aggregate power data obtained at the main breaker level of a residence or commercial establishment. Step power changes and power surges characterize appliances. These features are identified and the time of use and duration statistics are considered to match an observed sequence of power changes with the appliances being turned on and off. The time-dependent usage of appliances and their power consumption are then reconstructed.Type: GrantFiled: December 13, 2011Date of Patent: November 14, 2017Assignee: Fraunhofer USA, Inc.Inventor: Michael Zeifman
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Patent number: 9611501Abstract: Described herein is a method and a device for expediting delivery of an agent to a damaged bacterial cell. In one embodiment, the methods and devices are useful for screening candidate antibiotics. In another embodiment, the methods and devices described herein are used to determine susceptibility of bacteria to an antibiotic. The methods also provide a method for determining an appropriate antibiotic to treat an individual having a bacterial infection.Type: GrantFiled: May 29, 2014Date of Patent: April 4, 2017Assignees: Trustees of Boston University, Fraunhofer USA, INC.Inventors: Alexis Fay Sauer-Budge, Andre Sharon, Maxim Kalashnikov, Holger Wirz
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Patent number: 9498513Abstract: The present invention provides novel antimicrobial bacteria strains and uses thereof to prepare novel antimicrobial agents. Also provided are the novel antimicrobial agents.Type: GrantFiled: September 2, 2015Date of Patent: November 22, 2016Assignee: Fraunhofer USA Inc.Inventors: Megan R. Carpenter, Zusheng Li, Vadim Mett, Vidadi Yusibov
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Patent number: 9364530Abstract: The present invention relates to novel virus-like particles (VLPs) comprising a matrix protein derived from a first plant enveloped virus and a surface polypeptide. The surface polypeptide comprises (a) a surface exposed portion derived from a target polypeptide (b) a transmembrane domain, and (c) a cytosolic tail derived from a transmembrane (e.g., glycoprotein) of a second plant enveloped virus. The target polypeptide may be antigenic or therapeutic. The first and the second plant enveloped viruses may be the same. Either plant enveloped virus may be a plant rhabdovirus. Also provided are methods of making and using the VLPs.Type: GrantFiled: March 15, 2013Date of Patent: June 14, 2016Assignee: Fraunhofer USA, Inc.Inventors: Alexei Prokhnevsky, Vidadi Yusibov
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Publication number: 20160129388Abstract: Mesoporous aluminosilicate materials and methods of using the same are described.Type: ApplicationFiled: October 5, 2015Publication date: May 12, 2016Applicant: Fraunhofer USA, Inc.Inventors: Prabhakar Singh, Steven L. Suib, Ting Jiang, Wei Zhong, Tahereh Jafari
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Publication number: 20160122186Abstract: Mesoporous carbon material and methods of forming and using the same are provided.Type: ApplicationFiled: July 31, 2015Publication date: May 5, 2016Applicant: Fraunhofer USA, Inc.Inventors: Tahereh Jafari, Ting Jiang, Wei Zhong, Steven L. Suib, Prabhakar Singh
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Publication number: 20160072143Abstract: High temperature electrochemical systems and methods of capturing Cr species from a gas (e.g., oxidant gas) stream flowing in such systems are described herein.Type: ApplicationFiled: August 7, 2015Publication date: March 10, 2016Applicant: Fraunhofer USA, Inc.Inventors: Prabhakar Singh, Steven L. Suib, Mahesh B. Venkataraman, Venkata Manthina, Manoj K. Mahapatra, Ugur Pasaogullari
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Publication number: 20160059215Abstract: Graphene/manganese oxide-based structures (e.g., nanocomposites, films and membranes) are described herein, as well as methods of making the same.Type: ApplicationFiled: July 31, 2015Publication date: March 3, 2016Applicant: Fraunhofer USA, Inc.Inventor: . .
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Publication number: 20160036372Abstract: Photovoltaic systems and related techniques are provided. A method for commissioning a photovoltaic (PV) system may include obtaining data describing an arrangement of two or more components of the PV system; performing a test of the PV system, wherein performing the test includes determining whether the PV system complies with at least one PV system criterion based, at least in part, on at least a portion of the data describing the arrangement of the two or more components of the PV system; and in response to determining that the PV system complies with the at least one PV system criterion, activating the PV system and/or notifying a user of the PV system that the PV system complies with the at least one PV system criterion. The method may further include sending information associated with the PV system to a regulatory entity and/or an operator of an electrical grid.Type: ApplicationFiled: July 14, 2015Publication date: February 4, 2016Applicant: Fraunhofer USA, Inc.Inventors: Christian Hoepfner, Dirk E. Mahling, Matthew Alan Kromer, James R. Perkinson
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Publication number: 20160036234Abstract: Photovoltaic systems and related techniques are provided. A method for commissioning a photovoltaic (PV) system may include obtaining data describing an arrangement of two or more components of the PV system; performing a test of the PV system, wherein performing the test includes determining whether the PV system complies with at least one PV system criterion based, at least in part, on at least a portion of the data describing the arrangement of the two or more components of the PV system; and in response to determining that the PV system complies with the at least one PV system criterion, activating the PV system and/or notifying a user of the PV system that the PV system complies with the at least one PV system criterion. The method may further include sending information associated with the PV system to a regulatory entity and/or an operator of an electrical grid.Type: ApplicationFiled: July 14, 2015Publication date: February 4, 2016Applicant: Fraunhofer USA, Inc.Inventors: Oscar Hazel Del Olmo, Matthew Alan Kromer, Christian Hoepfner, Geoffrey Kinsey
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Publication number: 20160036381Abstract: Photovoltaic systems and related techniques are provided. A method for commissioning a photovoltaic (PV) system may include obtaining data describing an arrangement of two or more components of the PV system; performing a test of the PV system, wherein performing the test includes determining whether the PV system complies with at least one PV system criterion based, at least in part, on at least a portion of the data describing the arrangement of the two or more components of the PV system; and in response to determining that the PV system complies with the at least one PV system criterion, activating the PV system and/or notifying a user of the PV system that the PV system complies with the at least one PV system criterion. The method may further include sending information associated with the PV system to a regulatory entity and/or an operator of an electrical grid.Type: ApplicationFiled: July 14, 2015Publication date: February 4, 2016Applicant: Fraunhofer USA, Inc.Inventors: Matthew Alan Kromer, Christian Hoepfner, Dirk E. Mahling, James R. Perkinson
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Publication number: 20160036373Abstract: Photovoltaic systems and related techniques are provided. A method for commissioning a photovoltaic (PV) system may include obtaining data describing an arrangement of two or more components of the PV system; performing a test of the PV system, wherein performing the test includes determining whether the PV system complies with at least one PV system criterion based, at least in part, on at least a portion of the data describing the arrangement of the two or more components of the PV system; and in response to determining that the PV system complies with the at least one PV system criterion, activating the PV system and/or notifying a user of the PV system that the PV system complies with the at least one PV system criterion. The method may further include sending information associated with the PV system to a regulatory entity and/or an operator of an electrical grid.Type: ApplicationFiled: July 14, 2015Publication date: February 4, 2016Applicant: Fraunhofer USA, Inc.Inventors: Christian Hoepfner, Matthew Alan Kromer, Jacquie Ashmore Chakrabarty, Dirk E. Mahling, James R. Perkinson
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Publication number: 20150359844Abstract: The present invention provides novel antimicrobial bacteria strains and uses thereof to prepare novel antimicrobial agents. Also provided are the novel antimicrobial agents.Type: ApplicationFiled: September 2, 2015Publication date: December 17, 2015Applicant: Fraunhofer USA Inc.Inventors: Megan R. CARPENTER, Zusheng Li, Vadim Mett, Vidadi Yusibov
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Patent number: 9199250Abstract: The present invention relates to methods, devices and systems for separation and concentration of particles from liquid and fluid samples. In some embodiments, the separation/concentration is achieved by sequential centrifugation steps. In particular, one aspect of the invention relates to a separation/concentration device which comprises at least a first chamber (101) and a second chamber (103) connected by a first valve (111), whereby operation of the first valve controls the material transfer from the first chamber to the second chamber. In some embodiments, valve operation can be manually, semi-manually or automatically. Other aspects of the invention relate to single- or multi-chambered separation/concentrator devices, and methods and systems for use. Other aspects of the invention relate to devices for operation of the valves, e.g., semi-manual actuation devices, and automatic inertial activation devices and mechanical actuation devices present in purpose-built centrifuges.Type: GrantFiled: April 30, 2010Date of Patent: December 1, 2015Assignees: Trustees of Boston University, Fraunhofer USA, Inc.Inventors: Andre Sharon, Alexis Sauer-Budge, Aaron Size, Holger Wirz