Patents Assigned to Fresenius Kabl iPSUM S.R.L.
  • Process for the preparation of high purity glucagon
    Patent number: 11566058
    Abstract: The present invention provides an improved process for the preparation of high purity glucagon comprising the use of Xmb-protected amino acids, wherein may Xmb include, e.g., 2,4,6-trimethoxybenzyl, 2,4-dimethoxybenzyl, or 2-hydroxy-4-methoxybenzyl. The process also comprises the use of building blocks such as pseudoprolines to avoid aggregation and obtain the product in high yield and purity.
    Type: Grant
    Filed: June 18, 2020
    Date of Patent: January 31, 2023
    Assignee: Fresenius Kabl iPSUM S.R.L.
    Inventors: Andrea Orlandin, Antonio Ricci, Walter Cabri, Steve McIntyre, Alex Saunders