Abstract: Immobilization and magnetic extraction of pathogens and pathogen components The application describes a method for reducing the concentration of pathogens and/or pathogen components in an aqueous or body fluid sample. Specifically, the method relates to incubating the sample with superparamagnetic iron-based particles attached to a target binding peptide and immobilising the superparamagnetic iron-based particles with a magnetic field and thereby separating the pathogen-bound and/or pathogen component-bound superparamagnetic iron-based particles from the sample. Furthermore, the application relates to a method for identifying pathogens in an aqueous or body fluid sample a use of superparamagnetic iron-based particles for reducing the concentration of pathogens and/or pathogen components in an aqueous or body fluid sample. In addition, a use of superparamagnetic iron-based particles for identifying pathogens in an aqueous or body fluid sample is disclosed.

Abstract: The present invention relates to a nucleic acid molecule encoding a chain myeloid capable of specifically binding to CD33, CD16 and CD123, wherein said nucleic molecule comprises: (a) a nucleic add molecule encoding a protein represented by SEQ ID NO:1; (b) a nucleic acid molecule represented by SEQ ID NO:2; (c) the nucleic add molecule of (b), wherein each thymine is replaced by urea; (d) a nucleic acid molecule encoding a protein having at least 98% sequence identity to the protein of (a); or (e) a nucleic add molecule that is degenerate with respect to the nucleic acid molecule of (b) or (c). The present invention further relates to a vector comprising the nucleic acid molecule of the invention, a host cell transformed or transfected with the nucleic acid molecule or the vector of the invention, as well as to a method for the production of a single chain myeloid capable of specifically binding to CD33, CD16 and CD123.

Abstract: An apparatus determines a spatial position of an audio source in multi moving audio sources scenarios. The apparatus receives audio signal versions as local sound waves. The apparatus determines first and second probabilities for a direction of arrival of the audio signal version based on the audio signal versions received within a first time interval; determines third and fourth probabilities for the direction of arrival of the audio signal version based on the audio signal versions received within a second time interval; determines a first probability difference between the first and third probabilities; determines a second probability difference between the second and fourth probabilities; combines the third probability and the first probability difference to obtain an updated third probability; combines the fourth probability with the second probability difference to obtain an updated fourth probability; and determines the spatial position based on the updated third and fourth probabilities.

Abstract: The application describes a T-cell expressing a chimeric antigen receptor (‘CAR T-cell’) containing superparamagnetic iron-based particles (‘loaded CAR T-cell’) for use in treating a tumor. Said loaded CAR T-cell exhibits a reduced cytokine release upon binding to a cell of the tumor expressing an antigen being recognized by the CAR of the CAR T-cell, compared to a CAR T-cell not containing superparamagnetic iron-based particles (‘unloaded CAR T-cell’) under the same conditions. Furthermore, an in vitro method of generating a CAR T-cell containing superparamagnetic iron-based particles is described, whereby such loaded CAR T-cells are generated.

Abstract: In a method for producing a capacitor, a dielectric structure is generated in a trench of a semiconductor substrate. The dielectric structure includes a plurality of adjacent dielectric layers having opposing material tensions.

Abstract: The invention relates to a system for annotating car radar data, comprising: at least one radar arranged on a car for producing a radar image by means of radar measurement; at least one optical detection system arranged outside the car for producing a camera image; a segmentation unit, which is designed to subject a camera image produced by the optical detection system to semantic segmentation for forming a semantic grid in order to assign one of a plurality of object classes to the camera image pixel by pixel; a computing unit, which is designed to transfer the camera image and/or the radar image into a common coordinate system for co-registration; and an annotation unit, which is designed to carry out annotation of the radar image, in other words to allocate an object class to a radar target of the radar image, in such a way that the object class of the semantic grid of the co-registered camera image in which the radar target of the co-registered radar image is located is allocated to a particular radar tar

Abstract: Embodiments provide a terminal point of a communication system, wherein a control signal is emitted in the communication system for coordinating the participants of the communication system, wherein the control signal is transferred distributed in correspondence with a frequency hop-based occupancy of resources of the frequency band, indicated by a control signal hopping pattern, wherein the terminal point has a receiver, wherein a receive bandwidth of the receiver is smaller at least by the factor 3 than a bandwidth of the frequency hop-based occupancy of resources of the frequency band, indicated by the control signal hopping pattern, wherein the terminal point is configured to receive a reference signal, the reference signal having information on the control signal, wherein the terminal point is configured to receive the control signal based on the information on the control signal.

Abstract: The invention relates to a crystal growing unit comprising a crucible for producing and/or enlarging a single crystal. The crystal growing unit has a first thermal insulation with a first thermal conductivity and a second thermal insulation with a second thermal conductivity. The crucible has a crucible base, a crucible side wall and a crucible cover. The crucible side wall is indirectly or directly surrounded by the first thermal insulation. The second thermal insulation is arranged indirectly or directly above the crucible cover. The second thermal conductivity is greater than the first thermal conductivity.

Abstract: The present invention relates to a method for manufacturing an electronic or electrical system, the method comprising the layer-free production of at least one physical structure (101, 102) which is designed to guide electromagnetic waves, using at least one additively operating apparatus, wherein the layer-free production of the spatial, layer-free structure comprises the simultaneous or sequential application and/or removal of one or more materials in the spatial arrangement, as a result of which the electronic or electrical system is partially or completely formed. The invention further relates to a system which is manufactured in accordance with the method.

Abstract: Aspects of the present disclosure include conformationally restricted analogs of catecholamine type compounds (e.g., isoprenaline, adrenaline, noradrenaline) which activate ?2AR with high selectivity over ?1AR. The subject beta-2 selective adrenergic receptor agonist compounds may serve as bronchiodilators and find use in the treatment of a variety of bronchoconstrictive diseases and conditions. Also provided are compositions and methods for treating preterm labor. A method of treating acute asthma including administration of a subject compound to a subject in need thereof is provided. The subject method can provide for reduced undesirable side effects associated with non-selective ?-adrenergic receptor agonism, such as inotropic and chronotropic effects that leads to elevated blood pressure. The compounds can also be used to prevent or treat heart failure. Kits and compositions for practicing the subject methods are also provided.

Abstract: The invention relates to a method (MTH) for estimating the coverage area of a directive antenna of a local positioning system while setting up said system, said antenna being located in the vicinity of an area of interest, the method (MTH) comprising the following steps: —Distributing (DIS_TR) a plurality of transponders over the area of interest—Performing (MSD_SS) measurements of signal strength between the antenna and said transponders—Estimating (EST_CV) the coverage area by using said measurements.

Abstract: The invention relates to a locating method for localizing at least one object using wave-based signals, wherein a wave field emanates from the object to be localized and the wave field emanating from the object is received by a number N of receivers, at least one measurement signal is formed in every receiver, said measurement signal being dependent on the spatial and temporal distribution of the wave field and the phase progression of said measurement signal being characteristically influenced by the signal propagation time from the object to the receiver, wherein, for position locating, phase values for each of the at least two measurement signals are taken as measured phase values, and wherein the current position (P(k)) of the object to be located at the time k is determined by a comparison of at least one linear combination of the measured phase values with at least one linear combination of the associated hypothetical phase values, which result from the transmitter-receiver distance(s), and using a recu

Abstract: The invention refers to a composite wavelength converter (1) for an LED (100), comprising a substrate (10) and an epitaxial film (20) formed by liquid phase epitaxy on the top and bottom of the substrate (10). Furthermore, the invention refers to a method of preparation of a composite wavelength converter (1) for an LED (100). Furthermore, the invention refers to a white LED light source comprising an LED (100) and an inventive composite wavelength converter (1) mounted on a light emitting surface of the LED (100).

Abstract: Embodiments provide a transfer method for transferring data of variable length using a fixedly specified number of sub-data packets to which the data of variable length is distributed.

Abstract: Described herein, inter alia, are compositions and methods for modulating mu opioid receptor activity.

Abstract: Embodiments provide a transfer method for wirelessly transferring data in a communication system (e.g. a sensor network or telemetry system). The data includes core data and extension data, wherein the core data is encoded and distributed in an interleaved manner to a plurality of core sub-data packets, wherein the extension data is encoded and distributed in an interleaved manner to a plurality of extension sub-data packets, wherein at least a part of the core data contained in the core sub-data packets is needed for receiving the extension data or extension data packets.

Abstract: A Computer-implemented method is provided for encrypting data by a server in cooperation with a predetermined number of rate limiters. The method includes receiving, by the server, a user identification, and a password to be encrypted and creating a secret message, the secret message being a key suitable for use with a symmetric key encryption/decryption scheme. The method further includes generating, on the basis of a predetermined interactive cryptographic encryption protocol, a ciphertext which encrypts the user password, and the secret message using secret keys of the rate limiters of the subset, where the threshold is smaller than or equal to the number of rate limiters, and the protocol is adapted such that the server needs only to interact with a subset of the predetermined size of the number of rate limiters for decryption of the ciphertext to recover the secret message.

Abstract: The present invention relates to a method for determining in a subject's biological sample the relative proportions of papillary renal cell carcinoma (pRCC), clear cell renal cell carcinoma (ccRCC), and chromophobe renal cell carcinoma (chRCC), an array comprising capture molecules capable of specifically binding to RCC signature genes or coding sequences thereof or products encoded thereby, and the use of RCC signature genes for classifying a subject into a renal cell carcinoma (RCC) risk group and/or for determining in a subject's biological sample the relative proportions of pRCC, ccRCC, and chRCC.

Abstract: A particulate material and a process for the production thereof are provided, which particulate material comprises zeolitic particles having a crystalline structure, which contain as the main component a zeolite material having a zeolitic framework structure formed from Si, O and optionally Al, and/or a zeolite-like material having a zeolitic framework structure which is formed not only from Si, O and optionally Al, wherein the zeolitic particles are in the form of essentially spherical particles with nanometer dimensions.

Abstract: A transmitter is configured to operate in a mobile communication system according to a mobile communication standard (e.g., 3GPP), wherein resources of the communication system are divided into resources elements. The transmitter is also configured to transmit an additional telegram by separating the telegram into a plurality of data packets, each of the data packets being shorter than the telegram, and transmitting each of the data packets respectively in one of the resource elements.