Patents Assigned to Friedrich-Alexander-Universitat at Erlangen-Nurnberg
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Publication number: 20130303884Abstract: An imaging method for radiologically guiding an instrument during medical interventions on an object comprising: providing a first image of said object followed by providing updated images on-the-fly during the intervention to an operator by measuring an undersampled set of projections of said object and reconstructing said updated image based on changes between said first image or an update of said first image and said undersampled set of projections. The invention further relates to particular uses of the method and a system for radiologically guiding medical interventions on an object, comprising means to provide a first image of the object; an imaging apparatus measuring undersampled sets of projections; processing means in communication with the imaging apparatus for providing updated images on-the-fly during the intervention by reconstructing said updated image based on changes between said first image or an update of said first image and said undersampled set of projections.Type: ApplicationFiled: December 16, 2011Publication date: November 14, 2013Applicants: DEUTSCHES KREBSFORSCHUNGSZENTRUM, KLINIKUM MANNHEIM GMBH UNIVERSITATSKLINIKUM MEDIZINISCHE FAKULTAT MANNHEIM, FRIEDRICH-ALEXANDER-UNIVERSITAT ERLANGEN-NURNBERGInventors: Jan Kuntz, Soenke Bartling, Marc Kachelriess
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Publication number: 20130187595Abstract: The invention relates to a circuit for a system for contactless, inductive power transmission, in particular for use in supplying power to mobile devices, and to an associated charging circuit. The circuit comprises a primary-side circuit, which is disposed on a primary side and can be connected to a primary-side supply voltage, and a secondary-side circuit, which is disposed on a secondary side and can be connected to a load to be supplied with power. Furthermore a transformer stage having galvanic isolation is provided for the contactless transfer of power from the primary side over an air gap to the secondary side, wherein at least two magnetically coupled coils are provided for inductive power transmission and can be spatially separated from one another by distancing the secondary side from the primary side. The transformer stage has a resonant converter and the secondary-side circuit further comprises a restabilisation stage.Type: ApplicationFiled: May 27, 2011Publication date: July 25, 2013Applicants: Friedrich-Alexander-Universitat Erlangen-Nurnberg, Friwo Geratebau GMBHInventors: Alexander Bucher, Thomas Durbaum
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Patent number: 8098795Abstract: An X-ray detector for recording an image of an object that is moving relative to the detector includes a plurality of detector modules which are adjacently disposed so that they partially overlap. Using the detector modules, a TDI (Time Delayed Integration) is performed within each detector module. Subsequently an evaluation unit determines corrected measurement values of an overlap region by adding the measured values from the individual detector modules in the overlap region.Type: GrantFiled: September 29, 2009Date of Patent: January 17, 2012Assignee: Friedrich-Alexander-Universität Erlangen-NürnbergInventors: Tristan Nowak, Willi A. Kalender, Harry Schilling
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Patent number: 8090111Abstract: A signal separator, a method and computer product for determining a first output signal describing an audio content of a useful-signal source in a first microphone signal, and for determining a second output signal describing an audio content of the useful-signal source in a second microphone signal.Type: GrantFiled: June 12, 2007Date of Patent: January 3, 2012Assignees: Siemens Audiologische Technik GmbH, Friedrich-Alexander-Universität Erlangen-NürnbergInventors: Robert Aichner, Herbert Buchner, Walter Kellermann
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Patent number: 7983397Abstract: The present invention relates to a device and method for determining one or more characteristics of radiation using a sensor comprising one or more detector units capable of counting the number of photon or charged particle of said radiation impinging on said sensor in or above a determined energy range.Type: GrantFiled: February 8, 2007Date of Patent: July 19, 2011Assignee: Friedrich-Alexander-Universitat Erlangen-NurnbergInventors: Thilo Michel, Alexander Korn, Gisela Anton, Daniel Niederlohner, Michael Bohnel, Markus Firsching, Jurgen Durst
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Publication number: 20110143394Abstract: The invention relates to the field of biochemistry, molecular biology and microbiology. More specific the invention relates to methods and means for metabolic engineering and improved product formation by a filamentous micro-organism or a low G+C gram-positive bacterium. The invention discloses that DasR and DasR binding sites play an important and universal role in the control of gene expression in micro-organisms Based on this finding, the invention provides multiple useful applications, such as a method for regulating the expression of a gene of interest, a method for controlling metabolism, a method for decreasing undesired expression and many more. Moreover, the invention also provides means that can be used to establish said methods: for example a micro-organism in which the DasR binding site in operable linkage with a particular gene has been modified to obtain increased or decreased expression of a protein (being a desired or undesired protein) encoded by said gene.Type: ApplicationFiled: February 14, 2007Publication date: June 16, 2011Applicants: Universiteit Leiden, University of Liege, Friedrich-Alexander-Universitat Erlangen-NurnbergInventors: Sebastien Rigali, Mannfred F.B. Titgemeyer, Gilles P. van Wezel
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Publication number: 20110081549Abstract: An object of the present invention is to provide, even when a single crystal of a material other than AlN is used as a crystal, an AlN bulk single crystal having fewer defects and high quality, a method for producing such an AlN bulk single crystal, and a semiconductor device. A feature is to select, as a surface 1a of a hexagonal single crystal substrate serving as a seed crystal 1, a plane inclined at an angle of 10° to 80° with respect to the C-plane (FIG. 1(a)), and to grow an AlN single crystal 2 as a growth plane 2a on the surface 1a by a sublimation method (FIG. 1(b)).Type: ApplicationFiled: March 26, 2009Publication date: April 7, 2011Applicants: JFE MINERAL COMPANY, LTD., FRIEDRICH-ALEXANDER-UNIVERSITAT ERLANGEN-NURNBERG, CRYSTAL-N GMBHInventors: Shunro Nagata, Albrecht Winnacker, Boris M. Epelbaum, Matthias Bickermann, Octavian Filip, Paul Heimann
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Publication number: 20110051901Abstract: The present invention relates to a device and method for determining one or more characteristics of radiation using a sensor comprising one or more detector units capable of counting the number of photon or charged particle of said radiation impinging on said sensor in or above a determined energy range.Type: ApplicationFiled: February 8, 2007Publication date: March 3, 2011Applicant: FRIEDRICH-ALEXANDER-UNIVERSITAT ERLANGEN-NURNBERGInventors: Thilo Michel, Alexander Korn, Gisela Anton, Daniel Niederlohner, Michael Bohnel, Markus Firsching, Jurgen Durst
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Patent number: 7822291Abstract: A computer-implemented method for non-rigid multi-modal registration, includes providing trained data corresponding to previously registered images captured by different modalities, receiving two or more images captured by the different modalities, and registering the two or more images according to context information determined based on the trained data.Type: GrantFiled: October 26, 2005Date of Patent: October 26, 2010Assignees: Siemens Medical Solutions USA, Inc., Friedrich-Alexander-Universitat Erlangen-NurnbergInventors: Christoph Guetter, Chenyang Xu, Joachim Hornegger, Frank Sauer
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Patent number: 7642780Abstract: A magnetic resonance system has a basic magnet that generates a static basic magnetic field in an examination volume, and a whole-body antenna that emits a homogeneous radio-frequency field in the examination volume, the homogeneous radio-frequency field exhibiting an excitation frequency so that nuclei in an examination subject in the examination volume are excited to emit magnetic resonance signals, and a radio-frequency shield. The radio-frequency shield is arranged between the whole-body antenna and the basic magnet. The whole-body antenna is arranged between the radio-frequency shield and the examination volume. The radio-frequency shield is fashioned to exhibit a high shielding effect in a shielding frequency range that encompasses the excitation frequency. The shielding effect drops to a significantly lower shielding effect on both sides at side bands adjoining the shielding frequency range.Type: GrantFiled: March 21, 2008Date of Patent: January 5, 2010Assignees: Siemens Aktiengesellschaft, Friedrich-Alexander-Universitat Erlangen-NurnbergInventors: Dirk Diehl, Wolfgang Renz, Lorenz-Peter Schmidt, Ulrich Von Knobloch
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Patent number: 7601937Abstract: A photon detector has a photocathode for the photon-induced triggering of measuring electrons. Spatial position information is supplied by an at least one-dimensional electron-detector pixel array. An electron optics unit serves for guiding the measuring electrons to the array. Each pixel (19) has an electronic converter unit (20) for converting an analog measuring signal of the pixel (19) into a digital measuring signal, which incorporates a discriminator for background suppression. An electronic post-processing unit (39) serves for processing the digital measuring signal. The converter unit (20) of each pixel (19) has at least one clock generator (36), as well as at least one counter (29, 30), which is in signal connection with the clock generator (36) and discriminator (27) for generation of a digital timing signal.Type: GrantFiled: June 25, 2007Date of Patent: October 13, 2009Assignee: Friedrich-Alexander-Universität Erlangen-NürnbergInventors: Gisela Anton, Thilo Michel
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Publication number: 20090239311Abstract: In an ex vivo method of differentially diagnosing dementias selected from a group of demetias, which includes vascular dementias and frontotemporal lobe degenerations, a concentration of at least one carboxy-terminally truncated amyloid ? peptide species as a biomarker is determined in a body fluid obtained from a patient, the at least one carboxy-terminally truncated amyloid ? peptide species being selected from the group of species consisting of A?1-38, A?1-37 and A?1-39; and the concentration of the at least one carboxy-terminally truncated amyloid ? peptide species is compared to a threshold concentration value for the respective one carboxy-terminally truncated amyloid ? peptide species.Type: ApplicationFiled: May 15, 2009Publication date: September 24, 2009Applicants: Friedrich-Alexander-Universitat Erlangen-Nurnberg, Georg-August-Universitat Gottingen Stiftung Offentlichen Rechts (Universitatsmedizin)Inventors: Mirko BIBL, Brit MOLLENHAUER, Jens WILTFANG, Hermann ESSELMANN, Piotr LEWCZUK, Johannes KORNHUBER
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Patent number: 7401514Abstract: The invention relates to a gravity measurement apparatus comprising a torsion balance bearing a test mass. The torsion balance has a predetermined center of mass and is rotatable around a predetermined rotation axis, wherein the torsion balance is asymmetric in such a way that the center of mass of the torsion balance is offset to the rotation axis of the torsion balance.Type: GrantFiled: June 8, 2005Date of Patent: July 22, 2008Assignees: Friedrich-Alexander-Universitat at Erlangen-Nurnberg, Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V.Inventors: Lijun Wang, Felix Müller, Bruno Menegozzi
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Patent number: 7085198Abstract: A method for producing a computer-assisted real-time system that includes at least one processing unit. Data exchange between the processing unit and the environment or one or more additional processing units is synchronous or asynchronous. At least one real clock is allocated to the processing unit to correlate data exchange.Type: GrantFiled: September 3, 2001Date of Patent: August 1, 2006Assignee: Friedrich-Alexander-Universitat Erlangen-NurnbergInventors: Ralf Münzenberger, Frank Slomka, Matthias Dörfel, Oliver Bringmann
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Patent number: 5966790Abstract: A tool for separating mutually connected parts which has a head part and at least two spreading elements which are movably connected to the head part in such a way that a force or a pulse applied to the head part is converted in the spreading elements into a force component which is in the same direction and into a force component which is perpendicular thereto and which is operable to move the parts to be separated away from each other.Type: GrantFiled: January 30, 1998Date of Patent: October 19, 1999Assignee: Freistaat Bayern, vertreten durch die Friedrich-Alexander-Universitat Erlangen-Nurnberg, diese vertreten durch den Rektor Prof. Dr. Gotthard JasperInventor: Otto Meedt