Abstract: The invention relates to nutritional and pharmaceutical compositions comprising non-digestible galactooligosaccharides (GOS) and uses thereof. In particular, it relates to the use of GOS species in preventing or treating disease caused by bacterial toxins. Provided is the use of GOS having a polymerization degree of 5 or higher, preferably 6 or higher, for the manufacture of a nutritional or pharmaceutical composition for the treatment or prevention of an acute or chronic disease associated with or caused by the adhesion and/or uptake of a cholera toxin family member. Also provided is a method for providing a GOS fraction capable of inhibiting cholera toxin (Ctx) binding to GM1 and fractions obtainable thereby.

Abstract: Cup for the preparation of a liquid product, having a first chamber part (25) for holding a preparation substance, an inlet opening provided with a covering layer (16) with liquid-permeable perforations (17, 18, 19) for receiving a liquid suitable for the preparation substance, an outlet opening (24) for discharging the prepared beverage or dish, and a static mixer (5) which is in liquid communication with the outlet opening (24). The static mixer (5) is a multi-step mixer.

Abstract: Cup for preparation of a liquid product, having a first chamber part (25) for holding a preparation substance, an inlet opening provided with a covering layer (16) with liquid-permeable perforations (17, 18, 19) for receiving a liquid suitable for the preparation substance, an outlet opening (24) for discharging the prepared beverage or dish, and a static mixer (5) which is in liquid communication with the outlet opening (24). The first chamber part (25) is of a substantially conical shape on an inner side between the inlet opening and the static mixer (5).

Abstract: Cup for preparing a beverage by means of an appropriate holder (30) which is suitable for use in a hot water appliance. The cup (10) comprises a cup-shaped dish element (11) for holding a preparation substance, said cup-shaped dish element having an inlet aperture and an outlet aperture (24). The cup-shaped dish element (11) is provided on an open side with a covering layer (16), so that an interior space (25) of the cup (10) is formed for holding the preparation substance. The covering layer (16) is provided with liquid-permeable perforations and substantially the greater part of the surface of the covering layer (16) serves as the inlet aperture for receiving a liquid suitable for the preparation substance.

Abstract: The present invention relates to a functional milk fraction which can be used to reduce negative effects associated with the oral uptake of acidic foods and beverages, to a method of isolating said specific milk fraction and to the use of this milk fraction in compositions for oral care. The functional milk fraction can be used in edible products, especially to counteract the negative effects of the consumption of acidic foods and beverages.

Abstract: Dispenser system for dispensing a liquid product, in which a container containing a bag (20), containing therein the liquid product, can be placed in the dispenser system. The dispenser system (15) includes a gas injection element (9) that can be connected to the bag (20) for homogenising the liquid product in the bag (20). The dispenser system (15) further comprises a control unit (1) that is equipped to activate the gas injection element (9) depending on the product present in the bag (20). The container with bag (20) can have an identification element (21), containing data that are important for the operation of the dispenser system (15).

Abstract: A protein-free soluble foaming composition is provided which contains carbohydrate particles having a plurality of voids containing entrapped pressurized gas. The composition may include a surfactant and may be contained in a food product such as a beverage mix or an instant food. In addition, a method is provided for manufacturing the foaming composition in which the protein-free soluble foaming particles are heated and an external pressure exceeding atmospheric pressure is applied to the protein-free soluble foaming particles. The soluble foaming particles are cooled and the external gas pressure is released resulting in pressurized gas remaining in internal voids of the foaming composition.

Abstract: The invention relates to a method for conditioning liquid, neutral products which are intended for consumption or for processing into foods. In particular, the invention concerns a method for controlling the gas composition in such products at any time or during the complete treatment process. Further, the invention relates to the products obtained and obtainable from this method, which products possess improved properties and especially an improved microbiological quality.

Abstract: The invention relates to a method for conditioning milk and milk products, and in particular for controlling the gas composition in the milk at any time or during the complete treatment process. Further, the invention relates to the milk and milk products obtained and obtainable from this method, which milk and milk products possess improved properties. In particular, an improved light stability is obtained.

Abstract: Compositions comprising: (i) from 25% to 90% by weight of an edible oil; (ii) one or more sugar alcohols; and (iii) one or more reducing sugars; wherein the oil comprises at least 20% by weight of one or more carboxylic acids containing at least 18 carbon atoms and at least 2 carbon-carbon double bonds, or an ester thereof, and the weight ratio of (ii) to (iii) is from 2:1 to 1:40, exhibit good stability and other advantages and can be used in food products.

Abstract: The invention relates to compounds with an antihypertensive effect. More in particular, the invention relates to releasing ACE (angiotensin I-converting enzyme)-inhibitory peptides from whey proteins. The invention provides a method for enzymatically producing a protein hydrolysate with angiotensin-converting enzyme (ACE)-inhibitory activity, characterized by treatment of a beta-lactoglobulin (BLG)-containing substrate with a broad-spectrum endoprotease in a first reaction step followed by treatment with a proline-specific endoprotease in a second reaction step. The invention also relates to ACE-inhibitory hydrolysates obtainable according to such a method and use of the hydrolysates.

Abstract: The invention relates to methods and means for regulating gene expression and to CodY target sequences. CodY represses its target genes by binding to specific DNA sequences upstream of the respective genes. A conserved target site was identified by analyzing upstream sequences of derepressed genes in a delta codY L. lactis MG1363 derivative, as identified in a DNA micro-array study. Also, CodY target sequences from other gram-positive bacteria, like B. subtilis and Streptococcus are disclosed. Hence, the invention provides CodY target sequences that may be used in different applications to repress or derepress gene expression.

Abstract: An apparatus provided with a micro or ultrafiltration filter, wherein the filter is provided with a filter housing having a retentate side and a permeate side, wherein the retentate side and the permeate side are separated from each other by filter material, wherein a fluid supply pipe is connected to the retentate side and a permeate discharge pipe to the permeate side, wherein, in the permeate discharge pipe, a shut-off valve operable at a high frequency is provided and wherein means are connected to the permeate side for increasing the pressure in the permeate side when the said shut-off valve is closed to a value which is higher than the pressure on the retentate side.

Abstract: A method for treatment for deterioration of a mucosal barrier, an intestinal dysfunction or injury, suboptimal intestinal wall maturation of new-borns, undernutrition, suboptimal intestinal blood flow, allergy, sepsis, translocation of pathogenic bacteria through an intestinal wall, endotoxaemia, or viral diarrhoea, in which the method includes orally or enterally administering to a patient in need of such treatment an effective amount of an exogenous nutritional preparation consisting essentially of at least one of free glutamic acid and ?-keto acid.

Abstract: The invention relates to a method for purifying protein containing waste water, In which a) a first insoluble material is caused to form in the waste water, b) the mixture obtained in step a) is separated to form pre-purified waste water, c) the pre-purified waste water is treated with aerobic microorganisms and d) the mixture obtained in step c) is separated to form finely purified waste water, and in which step b) and step d) are carried out in the same device. Preferably, steps b) and d) are alternately carried out in the same device.

Abstract: The invention relates to a process for the preparation of milk and milk powders having a long storage life utilizing techniques which are known per se. To that end, a milk liquid is prepared, which is evaporated, and a fat fraction is added to the milk liquid in one or more effects of the evaporator. This process is particularly suitable for the preparation of a milk having a long storage life, in which unsaturated fatty acid chains are present.