Abstract: A gas separation centrifuge is provided with a housing having a top, a bottom and a plurality of joined side walls parallel to an axis and forming a predetermined regular polygon cross-sectional shape perpendicular to the axis. A rotor is mounted for coaxial rotation within the housing, including a plurality of inverted truncated pyramid plates forming the predetermined regular polygon shape at an outer periphery, and forming the predetermined regular polygon shape at an interior edge. The plurality of inverted truncated pyramid plates are stacked coaxially and are axially spaced apart to form planar channels therebetween and define an interior annular volume with openings therefrom into the planar channels. There are also openings through the outer periphery. A first plurality of stationary concentric input tubes extends into the interior annular volume.