Patents Assigned to Fuisz Pharmaceutical Ltd.
  • Patent number: 5034421
    Abstract: A spun product from a combination of a saccharide and a hydrophobic ingredient is hydrophilic with low concentrations of such ingredient but becomes increasingly hydrophobic as the concentration of the hydrophobic ingredient is increased, although the end product nevertheless acts hydrophilically when the water temperature is elevated. Larger ratios of hydrophobic substance-to-saccharide yields a spun fibrous product that has increased stability. Similar stabilization can be attained by adding either beeswax or a petrolatum to the saccharide either in the presence of or absence of a separate active ingredient. Examples are given for masking the taste of unpalatable medicaments or other ingestible substances. Delayed release burn or wound dressings are also described. Control with beeswax can also provide a time release tablet or the like when swallowed.
    Type: Grant
    Filed: March 20, 1989
    Date of Patent: July 23, 1991
    Assignee: Fuisz Pharmaceutical Ltd.
    Inventor: Richard C. Fuisz
  • Patent number: 5028632
    Abstract: The addition of an extremely small quantity of an anesthetizing agent such as phenol to a medicament dosed saccharide floss serves to numb the taste buds sufficiently that undesirable taste stimulation by the medicament is inhibited.
    Type: Grant
    Filed: August 10, 1989
    Date of Patent: July 2, 1991
    Assignee: Fuisz Pharmaceutical Ltd.
    Inventor: Richard C. Fuisz
  • Patent number: 5011532
    Abstract: Oleaginous substances such as vegetable oil, baby oil, olive oil, margarine, lanolin, cocoa butter and the like have their affinity for water altered by mixing the oleaginous substance with sugar and melt spinning the mixture in a cotton candy spinning machine or the equivalent. As so modified the product disperses autogenously in water forming a colloidal or colloidal-like dispersion. The modification enables such widely disparate procedures as incorporating shortening oil in a cake mix containing flour but no egg, producing a confection or medicated lozenge by dehydrating the dispersion and allowing the melted residue to solidify.
    Type: Grant
    Filed: December 13, 1988
    Date of Patent: April 30, 1991
    Assignee: Fuisz Pharmaceutical Ltd.
    Inventor: Richard C. Fuisz
  • Patent number: 4997856
    Abstract: Floss spun from a mixture of a saccharide and an oleaginous substance which includes a medicament distributed on or through the fibers is compacted and chopped by passing through a conventional "food grinder" or equivalent having an auger feed to a cutter and orifice plate outlet. The enclosed volume of the end product is less than 30% and preferably less than 15% of the as-spun volume of the floss. This volume reduction is accomplished without distroying the colloidal-like behavior of the product. The compressed particles are readily metered for producing dosage units within required tolerances.
    Type: Grant
    Filed: November 30, 1989
    Date of Patent: March 5, 1991
    Assignee: Fuisz Pharmaceutical Ltd.
    Inventor: Richard C. Fuisz
  • Patent number: 4873085
    Abstract: A melt spinnable carrier agent such as sugar is combined with a cosmetic then converted into fiber form by melt spinning with "cotton candy" fabricating equipment. The as-spun product is converted to compacted individual dosage units. Examples are presented for topical application. All applications utilize the extraordinarily rapid entry of the fiber form mass into solution upon contact with a solvent. When lactose is used it absorbs moisture from the air which is then either transferred to the hair or skin to maintain the moisture content of the latter or it prevents the hair or skin from drying out.
    Type: Grant
    Filed: March 18, 1988
    Date of Patent: October 10, 1989
    Assignee: Fuisz Pharmaceutical Ltd.
    Inventor: Richard C. Fuisz
  • Patent number: 4855326
    Abstract: A melt spinnable carrier agent such as sugar is combined with a medicament then converted into fiber form by melt spinning with "cotton candy" fabricating equipment. The as-spun product is converted to compacted individual dosage units. For certain medicaments a binding agent is added to the carrier agent. Examples are presented for oral administration, topical application, systemic and non-systemic, intravenous and intra-muscular infusion via multicameral containers. All applications utilize the extraordinarily rapid entry into solution upon contact with a solvent.
    Type: Grant
    Filed: March 18, 1988
    Date of Patent: August 8, 1989
    Assignee: Fuisz Pharmaceutical Ltd.
    Inventor: Richard C. Fuisz