Abstract: An object of present invention is to provide a compound or a salt thereof constituting lipid particles that can achieve a high nucleic acid encapsulation rate and excellent delivery of nucleic acids, and to provide lipid particles and pharmaceutical composition using the compound or a salt thereof, which can achieve a high nucleic acid encapsulation rate and excellent delivery of nucleic acids. According to an aspect of the present invention, a compound represented by Formula (1) or a salt thereof is provided. In the formula, each symbol has a meaning defined in the present specification.

Abstract: There are provided a washout processor and a washing method that prevent solid contents from being attached to a developed flexographic printing plate precursor again.

Abstract: A projector includes a projection lens and a projector body. In the projection lens, a U-shaped optical path is formed by optical axis to optical axis. A lens barrel is a U-shaped barrel. A housing of the projector body includes a storage section. The projection lens is supported rotatably about the optical axis with respect to the housing, in an up-down direction and a right-left direction of the housing perpendicular to the optical axis, between a first position where the projection lens is stored inside a storage section provided in the housing and a second position where the projection lens is protruding from the housing.

Abstract: An object of the present invention is to provide a manufacturing method of a learning model, a learning model, an estimation method, an image processing system, and a program, which are capable of efficiently generating a large amount of learning data and of performing training on a learning model to which the efficiently generated large amount of learning data is applied. A manufacturing method of a learning model includes acquiring a region of a normal object included in a processing target image as a first mask, generating a second mask by changing a state of the first mask, and performing training to estimate a difference between the second mask and the first mask as a region-of-interest or performing training to estimate the first mask from the second mask, using the first mask and the second mask as learning data.

Abstract: An object of the present invention is to provide a flexographic printing plate precursor in which reproducibility of microcells is improved in a case of being made into a flexographic printing plate, and durability of independent dots is improved, and a manufacturing method of a flexographic printing plate using the flexographic printing plate precursor. The flexographic printing plate precursor of the present invention includes, in the following order, an infrared ablation layer, a photosensitive resin layer, and a support, in which a content of a photopolymerization initiator contained in a surface layer region of the photosensitive resin layer from a surface on a side in contact with the infrared ablation layer up to 100 ?m in a thickness direction is larger than a content of a photopolymerization initiator contained in a remainder region of the photosensitive resin layer, which is closer to the support side than the surface layer region.

Abstract: An endoscopic submucosal injection material containing: a water-soluble resin having a weight-average molecular weight of 10,000 or more; an organic compound having two or more hydroxyl groups and having a molecular weight of 400 or less; and water is provided, in which the endoscopic submucosal injection material has an electrical conductivity of 500 mS/m or less, and an osmotic pressure ratio of the endoscopic submucosal injection material to physiological saline is 0.7 to 1.5.

Abstract: To generate an accurate three-dimensional ultrasound image even in a case where an ultrasound probe is moved. In an ultrasound diagnostic apparatus and a control method of the ultrasound diagnostic apparatus of the present invention, a two-dimensional image generation unit generates a plurality of two-dimensional ultrasound images while shifting an angle or a position of a scanning plane using a transducer array in a state where an ultrasound probe is fixed by being in contact with an examination location of a subject. A motion determination unit sequentially calculates a similarity degree of at least two two-dimensional ultrasound images, and sequentially determines whether or not a motion of the ultrasound probe is within a predetermined reference value according to the similarity degree.

Abstract: Provided are a control method of an ultrasound diagnostic apparatus and an ultrasound diagnostic apparatus that enable a user to smoothly and appropriately perform an examination. An ultrasound diagnostic apparatus includes: an ultrasound probe; an image acquisition unit that acquires an ultrasound image of a blood vessel using the ultrasound probe; a blood vessel detection unit that detects the blood vessel from the ultrasound image; an examination site discrimination unit that discriminates an examination site; an examination mode setting unit that sets an examination mode corresponding to the discriminated examination site; a compression detection unit that detects a compression motion on a body surface of a subject by the ultrasound probe; a compression motion determination unit that determines whether or not the detected compression motion is proper for the set examination mode; and a notification unit that notifies a user of a determination result by the compression motion determination unit.

Abstract: A light absorption anisotropic film that, when being applied to an image display device, it is easy to control a region where visibility is high and a region where visibility is low and viewing angle controllability is more excellent, an optical film, and an image display device. The light absorption anisotropic film contains a dichroic substance and a liquid crystal compound, in which the light absorption anisotropic film has a plurality of regions having different directions of transmittance central axes in an in-plane direction of the light absorption anisotropic film, in the plurality of regions, all angles ? between the transmittance central axes and a normal direction of a surface of the light absorption anisotropic film are in a range of 0° to 70°, and any of a specific requirement 1, a specific requirement 2, or a specific requirement 3 is satisfied.

Abstract: A sensor unit includes: a support member; first to third vibration damping members disposed on the support member; and a flexible print substrate including first to third sensor parts that detect information related to an image shake, in which the first vibration damping member has a hole portion, and the first vibration damping member is disposed such that at least a part of the first vibration damping member overlaps the first sensor part in a projection direction of the first sensor part.

Abstract: An ultrasound probe 11 includes a transducer array in which a plurality of transducers are arranged, and a housing 12 in which the transducer array is accommodated. The housing 12 has a grip portion 13 that extends in a determined direction, and a transducer array accommodation portion 14 that is connected to one end portion of the grip portion 13 in an extension direction and accommodates the transducer array. A probe support surface 13B that extends along the extension direction is defined in a surface on the other end portion side of the grip portion 13 in the extension direction. In a case where the ultrasound probe is placed on a flat placing surface with the probe support surface 13B being brought into contact with the placing surface, the ultrasound probe is in such a posture that a surface of the housing 12 in a portion positioned on the transducer array accommodation portion 14 side with respect to the probe support surface 13B is separated from the placing surface.

Abstract: A blur correction device includes a sensor that detects an amount of blurring of an imaging apparatus, a mechanical blur correction device that corrects blurring by moving an optical element included in the imaging apparatus based on the amount of blurring, an electronic blur correction circuit corrects the blurring based on the amount of blurring with respect to an image obtained through imaging by using the imaging apparatus, and a supplementary blur correction circuit that corrects the blurring by applying a FIR filter or an IIR filter with respect to the image obtained by imaging through sharing and operating the mechanical blur correction device and the electronic blur correction circuit at a predetermined ratio during exposure in the imaging apparatus.

Abstract: Provided are a disease label creation device, a disease label creation method, a disease label creation program, a learning device, and a disease detection model that can create a disease label for a simple X-ray image at a low annotation cost. An information acquisition unit of a first processor of a disease label creation device acquires a simple X-ray image, a three-dimensional CT image paired with the simple X-ray image, and a three-dimensional first disease label extracted from the CT image. A registration processing unit of the first processor performs registration between the simple X-ray image and the CT image. A disease label converter of the first processor converts the first disease label into a two-dimensional second disease label corresponding to the simple X-ray image on the basis of a result of the registration by the registration processing unit to create a disease label.

Abstract: An image processing device 10 includes a processor 12, and the processor 12 is configured to execute an image acquisition process of acquiring a first image in a first image space and a second image in a second image space different from the first image space, a first conversion process of converting the first image into an image in a third image space that is characterized by a region of interest, using a first converter, a second conversion process of converting the second image into an image in the third image space using a second converter, and a first similarity calculation process of calculating a first similarity between the first image and the second image in the third image space.

Abstract: An image analysis apparatus, an image analysis method, and a program for specifying a region of interest from an image in which an arrow is assigned to the region of interest are provided. The above problem is solved by an image analysis apparatus including at least one processor, and at least one memory in which an instruction to be executed by the at least one processor is stored, in which the at least one processor is configured to receive an image in which an arrow is assigned to a region of interest, specify the arrow, dispose one or more region-of-interest candidates that are candidates of the region of interest in accordance with a direction of the arrow and with a distance from the arrow, calculate an interest degree for each region-of-interest candidate, and specify the region of interest from among the region-of-interest candidates based on the interest degree.

Abstract: A disease-related processing section performs at least one of the calculation of an index value related to a stage of ulcerative colitis, the determination of the stage of the ulcerative colitis, or the determination of whether or not the ulcerative colitis has remitted, on the basis of the denseness of superficial blood vessels, intramucosal hemorrhage, and extramucosal hemorrhage obtained from a medical image.

Abstract: An image acquisition unit acquires a plurality of projection images corresponding to a plurality of radiation source positions in a case of tomosynthesis imaging. A reconstruction unit reconstructs all or a part of the plurality of projection images to generate a tomographic image on each of a plurality of tomographic planes of a subject. A feature point detecting unit detects at least one feature point from a plurality of the tomographic images. A positional shift amount derivation unit derives a positional shift amount between the plurality of projection images with the feature point as a reference on a corresponding tomographic plane corresponding to the tomographic image in which the feature point is detected. The reconstruction unit reconstructs the plurality of projection images by correcting the positional shift amount to generate a corrected tomographic image.

Abstract: A picked-up image that is obtained from the image pickup of a subject illuminated with illumination light and auxiliary measurement light is acquired. The picked-up image includes at least two first and second spectral images having different wavelength components. A first arithmetic image from which a first noise component hindering the detection of an irradiation position of the auxiliary measurement light is removed by first arithmetic processing based on the first and second spectral images is obtained.

Abstract: An image forming apparatus includes: an apparatus body having a receiving surface on which a document is placed and that is provided on a rear portion of an upper surface, the rear portion being positioned behind a front end of the upper surface; a reading unit provided on the rear portion such that the reading unit is openable and closable, the reading unit reading an image on the document while transporting the document; an inclined surface on which no operation unit is disposed, the inclined surface being continuously inclined downward from a front end of the rear portion to the front end of the upper surface; and a projecting portion provided on a front portion of the apparatus body at a position on a first side of the inclined surface in a left-right direction, the projecting portion projecting forward and upward with respect to the inclined surface.

Abstract: Provided are a material for pressure measurement, including a color forming layer that contains microcapsules A encapsulating an electron-donating colorless dye precursor and microcapsules B not encapsulating an electron-donating colorless dye precursor, in which a volume standard median diameter D50A of the microcapsules A and a volume standard median diameter D50B of the microcapsules B satisfy Equation 1; a material composition for pressure measurement; and a material set for pressure measurement: D50A<D50B??Equation 1.