Abstract: The disclosure relates to use of the HE4/HE4a marker(s) to assess endometrial and uterine cancer in a patient. The disclosure also relates to using tumors marks for diagnosis, grading and staging of endometrial and uterine cancers. The disclosure also relates to determining prognosis and treatment effectiveness of a patient who has been diagnosed with endometrial or uterine cancer.
Type:
Application
Filed:
April 8, 2024
Publication date:
August 29, 2024
Applicant:
FUJIREBIO DIAGNOSTICS, INC.
Inventors:
Richard MOORE, Elizabeth SOMERS, W. Jeffrey ALLARD
Abstract: The invention includes the use of the HE/HE4a markers to assess ovarian cancer in a subject. Included also are compositions and methods of using HE/HE4a marker for diagnosis, grading and staging of ovarian cancers, determining prognosis and treatment effectiveness of a subject who has been diagnosed with ovarian cancer.
Type:
Application
Filed:
July 1, 2020
Publication date:
October 15, 2020
Applicants:
PACIFIC NORTHWEST DIABETES RESEARCH INSTITUTE, FUJIREBIO DIAGNOSTICS, INC.
Inventors:
Ingegerd HELLSTROM, Karl-Erik HELLSTROM, John RAYCRAFT, Christian FERMÉR, Eva RÖIJER
Abstract: The disclosure relates to use of the HE4/HE4a marker(s) to assess endometrial and uterine cancer in a patient. The disclosure also relates to using tumors marks for diagnosis, grading and staging of endometrial and uterine cancers. The disclosure also relates to determining prognosis and treatment effectiveness of a patient who has been diagnosed with endometrial or uterine cancer.
Type:
Application
Filed:
February 4, 2020
Publication date:
September 17, 2020
Applicant:
FUJIREBIO DIAGNOSTICS, INC.
Inventors:
Richard MOORE, Elizabeth SOMERS, W. Jeffrey ALLARD
Abstract: The invention includes the use of the HE/HE4a markers to assess ovarian cancer in a subject. Included also are compositions and methods of using HE/HE4a marker for diagnosis, grading and staging of ovarian cancers, determining prognosis and treatment effectiveness of a subject who has been diagnosed with ovarian cancer.
Type:
Application
Filed:
October 19, 2017
Publication date:
March 1, 2018
Applicants:
PACIFIC NORTHWEST DIABETES RESEARCH INSTITUTE, FUJIREBIO DIAGNOSTICS, INC.
Inventors:
Ingegerd HELLSTROM, Karl-Erik HELLSTROM, John RAYCRAFT, Christian FERMÉR, Eva RÖIJER
Abstract: The invention includes the use of the HE/HE4a markers to assess ovarian cancer in a subject. Included also are compositions and methods of using HE/HE4a marker for diagnosis, grading and staging of ovarian cancers, determining prognosis and treatment effectiveness of a subject who has been diagnosed with ovarian cancer.
Type:
Grant
Filed:
February 17, 2011
Date of Patent:
November 21, 2017
Assignees:
PACIFIC NORTHWEST DIABETES RESEARCH INSTITUTE, FUJIREBIO DIAGNOSTICS, INC.
Inventors:
Ingegerd Hellstrom, Karl-Erik Hellstrom, John Raycraft, Christian Fermér, Eva Roijer
Abstract: The invention relates to methods and kits for assessing occurrence in patient urine of peptides having amino acid sequences related to those of mesothelin, megakaryocyte potentiating factor, and other peptides that have been associated with occurrence in the serum of mesothelioma patients. The methods and kits can be used to diagnose mesothelioma in a patient, to predict development of mesothelioma in an otherwise asymptomatic patient, or to assess the efficacy of a mesothelioma therapeutic method.
Type:
Application
Filed:
January 21, 2005
Publication date:
January 19, 2006
Applicant:
Fujirebio Diagnostics, Inc.
Inventors:
Daniel O'Shannessy, Niranjan Sardesai, Jennifer Bones
Abstract: The invention relates to methods and kits for assessing occurrence in patient mesothelial fluid of peptides having amino acid sequences related to those of mesothelin, megakaryocyte potentiating factor, and other peptides that have been associated with occurrence in the serum of mesothelioma patients. The methods and kits can be used to monitor the biochemical or pathological status of a component of the corresponding mesothelial cavity in a patient, to predict development of such a pathological status in an otherwise asymptomatic patient, or to assess the efficacy of a therapeutic method.
Type:
Application
Filed:
January 21, 2005
Publication date:
January 19, 2006
Applicant:
Fujirebio Diagnostics, Inc.
Inventors:
Daniel O'Shannessy, Niranjan Sardesai, Elizabeth Somers
Abstract: The invention relates to methods and kits for assessing occurrence in woman urine of peptides having amino acid sequences related to those of mesothelin, megakaryocyte potentiating factor, and other peptides that have been associated with occurrence in the serum of ovarian cancer patients. The methods and kits can be used to diagnose ovarian cancer in a woman, to predict development of ovarian cancer in an otherwise asymptomatic woman, or to assess the efficacy of an ovarian cancer therapeutic method.