Abstract: An image processing device acquires an examination video in which an observation target is imaged in a video endoscopic examination of swallowing, performs recognition processing on the examination video for each frame image, to assign stage information indicating that an image shows which stage of the observation target among a plurality of swallowing stages set in advance to each of the frame images, and calculates a feature value indicating a feature related to swallowing of a subject person having the observation target based on the stage information assigned to each of a plurality of the frame images included in the examination video.

Abstract: An image acquisition unit acquires an examination image. A first frame classification unit classifies each frame of the examination image into any one of a swallowing-in-progress frame in which swallowing is in progress or a swallowing-not-in-progress frame in which the swallowing is not in progress. A swallowing block generation unit integrates, in a case in which a temporal interval between the swallowing-in-progress frames temporally adjacent to each other is equal to or less than a first threshold value, at least the adjacent swallowing-in-progress frames as a swallowing block.

Abstract: A medical information display apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to display information on the basis of volume data including at least a lung. The processing circuitry is configured to display a first index value based on an anatomical structure of the lung and a second index value based on the volume data related to the lung, so as to be kept in correspondence with each other.

Abstract: There are provided a method of assisting diagnosis of a hematological tumor, including using, as an indicator, a decrease in an amount of kynurenic acid in a subject-derived specimen, or using, as an indicator, a ratio between at least one amount selected from the group consisting of an amount of anthranilic acid, an amount of kynurenine, an amount of 3-hydroxyanthranilic acid, an amount of 3-hydroxykynurenine, and an amount of tryptophan, and the amount of kynurenic acid in the subject-derived specimen, a method of obtaining data for diagnosis of a hematological tumor, and a kit.

Abstract: An endoscope system that illuminates an object and captures reflected light from the object includes a control processor. The control processor acquires an examination image and determines whether the examination image shows a swallowing state or a non-swallowing state. In addition, the control processor detects a high pixel value region from the examination image and determines that the examination image shows the swallowing state in a case in which an area of the high pixel value region is equal to or greater than a first threshold value. Further, the control processor performs grayscale conversion on the examination image to obtain a grayscale image and performs a binarization process for obtaining the high pixel value region in a case in which a density value of a pixel of the grayscale image is equal to or greater than a second threshold value.

Abstract: The present invention provides a method for separating pituitary hormone-producing cells and/or progenitor cells thereof, said method comprising a step for separating CD49c-expressing cells from a cell aggregate including adenohypophysis and/or a progenitor tissue thereof, and a hypothalamic neuroepithelial tissue.

Abstract: The purpose of the present disclosure is to provide a technique that can contribute to less invasive or more reliable diagnosis of lymphocytic anterior hypophysitis and its related diseases. For this purpose, the KCNMA1 (calcium-activated potassium channel subunit alpha-1) protein or an epitope thereof is used as a diagnostic agent for lymphocytic anterior hypophysitis.

Abstract: A processor included in the image processing device acquires a medical image, outputs observation target identification information indicating an observation support target part or indicating that the medical image is out of an observation support target by inputting the medical image to an observation target identification algorithm, selects, from a plurality of observation support algorithms, one specific observation support algorithm based on the observation target identification information, outputs observation support information by inputting the medical image to the specific observation support algorithm, and performs a control of notifying of the observation support information.

Abstract: Provided is an epithelial tissue stem cell derived from an adult, which lacks at least one tumor suppressor gene.

Abstract: A medical image processing apparatus includes processing circuitry.

Abstract: The present invention provides a method for efficiently separating and purifying functional pituitary hormone-producing cells and/or progenitor cells thereof from differentiated tissues derived from pluripotent stem cells.

Abstract: A medical information display apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to display information on the basis of volume data including at least a lung. The processing circuitry is configured to display a first index value based on an anatomical structure of the lung and a second index value based on the volume data related to the lung, so as to be kept in correspondence with each other.

Abstract: An endoscope system that illuminates an object and captures reflected light from the object includes a control processor. The control processor acquires an examination image and determines whether the examination image shows a swallowing state or a non-swallowing state. In addition, the control processor detects a high pixel value region from the examination image and determines that the examination image shows the swallowing state in a case in which an area of the high pixel value region is equal to or greater than a first threshold value. Further, the control processor performs grayscale conversion on the examination image to obtain a grayscale image and performs a binarization process for obtaining the high pixel value region in a case in which a density value of a pixel of the grayscale image is equal to or greater than a second threshold value.

Abstract: The present invention is a cytocidal agent including a peptide consisting of an amino acid sequence represented by SEQ ID NO: 1 and a site selectively binding to a target molecule, in which the peptide consisting of an amino acid sequence represented by SEQ ID NO: 1 is a peptide exclusively consisting of L-amino acids, a peptide in which, in amino acid sequences represented by SEQ ID NO: 1, the first to the 14th amino acids are D-amino acids, and the 15th to 19th amino acids are L-amino acids, a peptide in which, in amino acid sequences represented by SEQ ID NO: 1, the first to 14th amino acids are L-amino acids, and the 15th to the 19th amino acids are D-amino acids, or a peptide exclusively consisting of D-amino acids.

Abstract: An object of the present invention is to provide a peptide drug that is able to selectively induce apoptosis in target cells. The present invention is a cytocidal agent containing a fusion peptide of an endosome escape peptide and an apoptosis-inducing peptide, which consists of an amino acid sequence represented by SEQ ID NO: 1, and the said cytocidal agent as a therapeutic agent for a disease caused by abnormal proliferation of cells.

Abstract: A medical image processing apparatus according to an embodiment includes processing circuitry. The processing circuitry sets a first region of interest in a region corresponding to cardiac muscle on a cross-section of a heart included in image data. The processing circuitry further sets a second region of interest that is larger than the first region of interest in a region including the region. The processing circuitry determines a threshold for determining a range of signal values used for blood flow dynamic analysis on the image data based on a frequency distribution of signal values in the first region of interest. The processing circuitry carries out blood flow dynamic analysis on the second region of interest using signal values included in a range based on the threshold.

Abstract: An image processing apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to acquire pieces of change information indicating temporal changes in computed tomography (CT) values of a myocardium and a right ventricular of a subject based on a plurality of chronologically consecutive images that are generated by an X-ray CT apparatus by scanning the subject to which a contrast agent is administered. The processing circuitry is configured to correct the piece of change information on the myocardium based on the piece of change information on the right ventricular.

Abstract: A medical image processing apparatus according to an embodiment includes processing circuitry. The processing circuitry sets a first region of interest in a region corresponding to cardiac muscle on a cross-section of a heart included in image data. The processing circuitry further sets a second region of interest that is larger than the first region of interest in a region including the region. The processing circuitry determines a threshold for determining a range of signal values used for blood flow dynamic analysis on the image data based on a frequency distribution of signal values in the first region of interest. The processing circuitry carries out blood flow dynamic analysis on the second region of interest using signal values included in a range based on the threshold.