Abstract: SP1 and modified SP1 variant polypeptides capable of forming reversible molecular associations with substances, compositions-of-matter comprising same, and uses thereof are provided.
Type:
Application
Filed:
June 7, 2015
Publication date:
October 1, 2015
Applicants:
Fulcrum SP Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem
Inventors:
Amnon WOLF, Yehonathan Pouny, Ira Marton, Or Dgany, Arie Altman, Oded Shoseyov
Abstract: SP1 and modified SP1 variant polypeptides capable of forming reversible molecular associations with substances, compositions-of-matter comprising same, and uses thereof are provided.
Type:
Grant
Filed:
July 9, 2006
Date of Patent:
June 9, 2015
Assignees:
Fulcrum SP Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem
Inventors:
Amnon Wolf, Yehonathan Pouny, Ira Marton, Or Dgany, Arie Altman, Oded Shoseyov
Abstract: SP1 and modified SP1 variant polypeptides capable of forming reversible molecular associations with substances, compositions-of-matter comprising same, and uses thereof are provided.
Type:
Application
Filed:
February 27, 2014
Publication date:
June 26, 2014
Applicants:
Yissum Research Development Company of the Hebrew University of Jerusalem, Fulcrum SP Ltd.
Inventors:
Amnon WOLF, Yehonathan Pouny, Ira Marton, Or Dgany, Arie Altman, Oded Shoseyov
Abstract: SP1 and modified SP1 variant polypeptides capable of forming reversible molecular associations with substances, compositions-of-matter comprising same, and uses thereof are provided.
Type:
Application
Filed:
July 9, 2006
Publication date:
March 5, 2009
Applicants:
Fulcrum SP Ltd., Yissum Research Development Co. of the Hebrew University of Jerusalem
Inventors:
Amnon Wolf, Yenonathan Pouny, Ira Marton, Or Dgany, Arie Altman, Oded Shoseyov
Abstract: Novel denaturant-stable, protease resistant, homo-oligomeric proteins, also referred to herein as stable proteins (SPs), having chaperone-like activity; methods of production and purification of SPs; nucleic acids encoding SPs; methods of isolating nucleic acids encoding SPs; antibodies recognizing SPs; the use of SPs for stabilizing, refolding, repairing, preventing aggregation and de-aggregating macromolecules such as proteins; fusion proteins including SPs; nucleic acid constructs encoding the fusion proteins; and their uses in a variety of methods and applications.
Type:
Grant
Filed:
September 4, 2002
Date of Patent:
August 7, 2007
Assignees:
Yissum Research Development Company of the Hebrew University of Jerusalem, Fulcrum SP Ltd.
Inventors:
Wangxia Wang, Dan Pelah, Tal Alegrand, Yehonathan Pouny, Ira Marton, Amnon Wolf, Oded Shoseyov, Arie Altman