Patents Assigned to Funai Kakuhin Kogyo Kabushiki Kaisha
  • Ester derivatives of alkoxybenzoyldeoxyfluorouridine
    Patent number: 4425335
    Abstract: New ester derivatives of alkoxybenzoyldeoxyfluorouridine of the general formula ##STR1## wherein R stands for an alkoxy group having 1 to 4 carbon atoms, m for 1 or 2, and n for 3 or 4 with the proviso that when m is 2, the adjacent two R's may be combined to form an alkylenedioxy group as a whole. These derivatives are prepared by acylating a 2'-deoxy-3',5'-di-O-alkylcarbonyl-5-fluorouridine with corresponding benzoyl halides and are useful as active ingredients for anti-tumor agents, especially for oral administration.
    Type: Grant
    Filed: August 10, 1981
    Date of Patent: January 10, 1984
    Assignee: Funai Kakuhin Kogyo Kabushiki Kaisha
    Inventors: Setsuro Fujii, Bompei Yasui, Mitsuo Nakamura, Mitsuru Hirohashi, Tomohisa Miyamoto, Kazuko Ando, Iwao Hashimoto, Naoki Umeda, Masahiro Kawasaki