Abstract: A method for fabricating a structured surface, includes: providing a transparent substrate; disposing a dewettable film over the substrate; annealing the dewettable film to form a plurality of islands; forming a coating over the plurality of islands; and etching the plurality of islands to form a structured array of surface features in the coating. A structured polymer and/or structured glass, includes: a structured array of surface features, such that the structured array of surface features has at least one dimension in a range of 0.5 nm to 5000 nm.
Type:
Grant
Filed:
March 31, 2020
Date of Patent:
May 28, 2024
Assignees:
FUNDACIÓ INSTITUT DE CIÈNCIES FOTÒNIQUES, INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS
Inventors:
Prantik Mazumder, Valerio Pruneri, Juan Rombaut
Abstract: An optical system configured to apply a relative phase modulation between two orthogonal polarization modes using a double pass configuration, wherein the system is configured to act independently on each polarization state.
Type:
Application
Filed:
October 4, 2023
Publication date:
April 25, 2024
Applicants:
Fundació Institut de Ciències Fotòniques, Institució Catalana de Recerca i Estudis Avançats
Abstract: The invention provides means and methods for inhibiting growth of a cancer. The means in some embodiments comprise proteins and antibodies that binds an extracellular part of a membrane associated member of the epidermal growth factor (EGF) receptor family and an extracellular part of a membrane associated member of a WNT signaling pathway. Further provided are various cells and assays that are helpful in the production of the proteins, antibodies and cells.
Type:
Grant
Filed:
October 21, 2016
Date of Patent:
March 26, 2024
Assignees:
Merus N.V., Fundacio Institut de Recerca Biomedica, Institució Catalana de Recerca I Estudis Avancats
Inventors:
Mark Throsby, Ton Logtenberg, Johannes Carolus Clevers, Robert Gerhardus Jacob Vries, Eduard Batlle, Bram Herpers
Abstract: The present invention relates to a method for the diagnosis or the prognosis of metastasis in lung cancer which comprises determining if the c-MAF gene is amplified in a primary tumor sample. Likewise, the invention also relates to a method for the diagnosis or the prognosis of metastasis in lung cancer, as well as to a method for determining the tendency to develop bone metastasis with respect to metastasis in other organs, which comprise determining the c-MAF gene expression level. Finally, the invention relates to the use of a c-MAF inhibitor as therapeutic target for treating the lung cancer.
Type:
Application
Filed:
June 6, 2013
Publication date:
June 4, 2015
Applicant:
Fundació Catalana de Recerca i Estudis Avançats