Patents Assigned to Fundació Institut D'lnvestigació Biomedica De Bellvitge (í DIBELL)
  • Adenovirus comprising an albumin-binding moiety
    Patent number: 11578104
    Abstract: The invention relates to a recombinant adenovirus comprising an albumin-binding moiety on the outer surface of the adenoviral hexon protein, pharmaceutical compositions containing it and its medical use. Particularly, the invention relates to an oncolytic adenovirus comprising a sequence encoding an albumin-binding moiety inserted in the hypervariable region 1 (HVR1) of the hexon protein coding sequence and its use in the prevention and/or treatment of cancer.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: February 14, 2023
    Assignees: Fundació Institut D'lnvestigació Biomedica De Bellvitge (í DIBELL), INSTITUT CATALA D'ONCOLOGIA (ICO)
    Inventors: Ramon Alemany Bonastre, Luis Alfonso Rojas Expósito