Abstract: Novel compounds for use in cognition improvement It relates to certain compounds having a polycyclic structure and a —(C?O)NRaRb moiety, wherein the polycyclic structure comprises at least three ring systems, wherein one ring system is a polycyclic ring system comprising from 2 to 4 rings; at least one ring is an aromatic ring; and wherein the structure comprises at least 3 nitrogen atoms and 1 oxygen atom. It also relates to pharmaceutical compositions containing them, and to their use in medicine, in particular in the treatment and/or prevention of neurological disorders coursing with a cognition deficit or impairment, or neurode-generative diseases.
Type:
Grant
Filed:
August 3, 2015
Date of Patent:
May 15, 2018
Assignee:
FUNDACIÓN LA INVESTIGACIÓN MÉDICA APLICADA
Inventors:
María del Mar Cuadrado Tejedor, Ana María García Osta, Julen Oyarzabal Santamarina, Maria Obdulia Rabal Gracia, Juan Antonio Sánchez Arias, Ana Ugarte Baztán