Patents Assigned to Fundacio Institut De Recerca Hospital Universitari Vall D'Hebron
  • Genetically modified mesenchymal stem cells expressing sST2 for the treatment of airway immune inflammatory and lung disease
    Patent number: 9339518
    Abstract: The present invention relates to mesenchymal stem cells (MSC) genetically modified to express sST2 or parts thereof for use in the treatment of airway immune inflammatory and lung diseases, wherein said mesenchymal stem cells are not human embryonic stem cells. The present invention also relates to pharmaceutical compositions comprising said mesenchymal stem cells.
    Type: Grant
    Filed: November 23, 2012
    Date of Patent: May 17, 2016
    Assignees: Fundacio Institut D'Investigacio Biomedica De Bellvitge (IDIBELL), Ciber Enfermedades Respiratorias, Fundacio Institut De Recerca Hospital Universitari Vall D'Hebron
    Inventors: Josep Maria Aran Perramon, Maria Jesus Cruz Carmona, Itziar Martinez Gonzalez, Oriol Roca Gas, Joan Ramon Masclans Enviz, Javier Munoz Gall
  • Markers for selecting personalized therapies for the treatment of cancer
    Patent number: 9028831
    Abstract: The invention relates to the identification of aprataxin (APTX) expression levels as a marker for the response to topoisomerase I inhibitor-based therapies in patients with cancer and, more particularly, colon cancer. The invention also relates to methods for treating patients with cancer who have low APTX expression levels by means of administering a topoisomerase I inhibitor to said patients.
    Type: Grant
    Filed: September 1, 2010
    Date of Patent: May 12, 2015
    Assignee: Fundació Institut de Recerca Hospital Universitari Vall d'Hebron, Fundació Privado
    Inventors: Diego Arango Del Corro, Simó Schwartz Navarro, John Martin Mariadason
  • ENGINEERED STEM CELLS AND THEIR THERAPEUTIC USE
    Publication number: 20140315298
    Abstract: The present invention relates to mesenchymal stem cells (MSC) genetically modified to express sST2 or parts thereof for use in the treatment of airway immune inflammatory and lung diseases, wherein said mesenchymal stem cells are not human embryonic stem cells. The present invention also relates to pharmaceutical compositions comprising said mesenchymal stem cells.
    Type: Application
    Filed: November 23, 2012
    Publication date: October 23, 2014
    Applicants: Fundacio Institut D'Investigacio Biomedica De Bellvitge (IDIBELL), Ciber Enfermedades Respiratorias, Fundacio Institut De Recerca Hospital Universitari Vall D'Hebron
    Inventors: Josep Maria Aran Perramon, Maria Jesus Cruz Carmona, Itziar Martinez Gonzalez, Oriol Roca Gas, Joan Ramon Masclans Enviz, Javier Munoz Gall
  • METHODS AND KITS FOR THE DIAGNOSIS OF PROSTATE CANCER
    Publication number: 20130171653
    Abstract: The present invention relates to the use of PSGR, a member of the G-protein-coupled olfactory receptor family which is over-expressed in prostate cancer tissue, as a marker suitable for an urine-based diagnostic test for prostate cancer which require only typical prostate manipulation and sample acquisition scenarios avoiding invasive tissue collection.
    Type: Application
    Filed: July 14, 2011
    Publication date: July 4, 2013
    Applicant: FUNDACIÓ INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL D'HEBRON, FUNDACIÓ PRIVADA
    Inventors: Andreas Doll, Marina Rigau Resina, Miguel Abal Posada, Juan Morote Robles, Jaume Reventós Puigjaner
  • MARKERS FOR SELECTING PERSONALIZED THERAPIES FOR THE TREATMENT OF CANCER
    Publication number: 20120231020
    Abstract: The invention relates to the identification of aprataxin (APTX) expression levels as a marker for the response to topoisomerase I inhibitor-based therapies in patients with cancer and, more particularly, colon cancer. The invention also relates to methods for treating patients with cancer who have low APTX expression levels by means of administering a topoisomerase I inhibitor to said patients.
    Type: Application
    Filed: September 1, 2010
    Publication date: September 13, 2012
    Applicant: Fundacio Institut de Recerca Hospital Universitari Vall d'Hebron, Fundació Privada
    Inventors: Diego Arango Del Corro, Simó Schwartz Navarro, John Martin Mariadason